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Dr Sudhir Kumar MD DM🇮🇳 Profile picture
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Mar 13 • 7 tweets • 2 min read
Drinking hot tea could increase the risk of esophageal cancer

1. Drinking tea is known to lower the risk of cancers, however, if tea is consumed hot, the risk of esophagus (food pipe) cancer can increase.
#MedTwitter #Cancer #tea
doi.org/10.3389%2Ffnut…
2. The overall results of the meta-analysis showed that people who drank hot tea had 77% higher risk of esophageal cancer than those who do not drink hot tea.
3. Green tea is rich in polyphenols, which have been extensively studied as a cancer chemo-preventive agent.
Epigallocatechin gallate (EGCG), the most abundant and active compound in tea, was reported to block cancer progression.
4. The potential thermal injury (due to boiling water in hot tea) should be considered because very hot beverages are identified by the International Agency for Research on Cancer (IARC) monograph as Category 2A carcinogens for esophageal small cell carcinoma (ESCC).
5. The tea temperature ≥60°C significantly increases the risk of ESCC compared with temperature <60°C.
The risk of esophageal cancer was moderately increased when the tea temperature was 60-69°C, and temperature above 70°C was associated with a high risk of esophageal cancer.
6. Take home message
*Very hot tea consumption can increase the risk of esophagus cancer.
*Enjoy the tea but ensure it is not boiling hot (hot tea could burn the taste buds too, so the food would become tasteless).
7. The commonest risk factors for esophagus cancers are alcohol consumption & smoking- so, these should be avoided.
Limitation of the study- this study looked at association and so, cause and effect can not be proved. The temperature was not measured and it was only an estimate.

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Non-nutritive sweetened beverages (NNSB) could be a viable alternative for sugar-sweetened beverages (SSB) in people trying to cut calories

1. Harmful effects of SSB such as soft drinks & packaged juices on diabetes and weight are well known. Are NNSBs an alternative in them?
2. A recent systematic review compared the acute (short-duration) impacts of NNSBs and SSBs on metabolic and endocrine parameters. Thirty-six trials involving 472 predominantly healthy participants were included.
doi.org/10.3390/nu1504…
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#medTwitter #neurotwitter
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A teenager referred with "difficult to control" fits needed non-drug approach for controlling fits

1. 15-year old Rishi had been having fits for the past three months. He used to have jerky movements of hands and legs that lasted several hours and occurred 15-20 times per day.
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1. The dose response between long-term endurance exercises such as running or cycling & coronary artery disease (CAD) is a subject of debate
1a. A recent study looked at the association between long-term endurance exercises and prevalence of coronary artery plaques.
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group 2 started after age 30, and
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#running #cycling #endurance #HeartAttack
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Dr Sudhir Kumar MD DM🇮🇳 Profile picture
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Lack of sleep (<5 h) and excessive sleep (>9 h), both increase the risk of heart attack
1. Insomnia (lack of sleep) is not considered a traditional risk factor for heart attack.
A recent study examined the association between sleep duration and risk of heart attacks.
#MedTwitter
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doi.org/10.1002/clc.23…
3. Excessive #sleep also increased the risk of #heartattack.
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Sleeping >9 hours and sleeping <5 hours , both increased the risk of heart attack.
#CardioTwitter
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