There is a new strain of #SARSCoV2 which is on the prowl in India. It is called #XBB1.16 and is highly transmissible. It has also been called #Arcutus. These are very early days for us to know the severity of the disease that can be caused by this variant.
There are very important mutations in this variant which affect the immunity of the infected people. #INSACOG, #GISAID and #WHO confirmed the presence of new variant in India.
Last December, there was a slight increase in the number of cases when the Government has cautioned the state governments. I have asked the government not to worry except to monitor for new strains. Only if a new strain comes along, the disease dynamics will changes. XBB 1.5 was… twitter.com/i/web/status/1…
This time it is different. This time there is a new variant. Please be careful. Because early in the uptick of infections, while we still don’t know much about the new variant, it is better not to get exposed to the virus. As the time progresses and we know for sure that the… twitter.com/i/web/status/1…
So bring the mask back on. DONT PANIC but don’t be complacent either. Be especially careful about the small indoor closed room gatherings. Schools should focus on increasing ventilation.
Special thanks to @vipintukur who has been warning about this variant from its earliest detection.
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The #Covid situation in #China is alarming. Let’s see how it may affect India. #thermonuclearbad (pic not representative).
Sudden lifting of Covid restrictions in China after December 7th, (in response to protests against the zero Covid policy) led to massive increase in Covid numbers. The Hospitalisations and deaths may increase.
The variants in circulation in China are #Omicron sub variants. Mostly BF7; which is a subvariant of BA5. (BA 5.2.1.7). This variant has already been spotted in several countries. It spreads alarmingly fast (R0 > 10). It escapes immunity.
A 50yr old educator (he has 300k YouTube followers, he tells me while on the cathlab table) had breathlessness, chest and abdominal discomfort along with swelling of feet. Examination and echo showed that he has a massive “pericardial effusion” 1/6 twitter.com/i/web/status/1…
Normally Heart has a covering: pericardium. Space between Heart and this covering has a very small quantity of fluid. If the fluid becomes more because of infection, inflammation, cancer or any other disease, the heart may get compressed. This is called “cardiac Tamponade”. 2/6
“Cardiac Tamponade” is a dangerous situation and may lead to sudden death of not treated quickly. Immediate drainage of the excess fluid with a needle will save the life of the patient. 3/6
This 🧵 contains important information about #hearthealth.
58 year old gentleman from Canada came to #PulseHeart with chest pain of more than 12 hours duration. His ECG showed a major heart attack. 1/n
He delayed seeking medical attention because he had a heart check up done in the past few months and he was told that his heart is normal. The check up included ECG and an ECHO. 2/n
On the angiogram done immediately, (this Sunday), he had a total block of one of the major blood vessels supplying the heart. 3/n
భారతదేశాన్ని ప్రపంచానికి వాణిజ్య రాజధాని లేదా విద్యా రాజధాని అని ఎవరూ పిలవకపోయినా, మధుమేహ రాజధాని అని మాత్రం అందరూ పిలుస్తున్నారు.
2/8
గుండె జబ్బులు తారాస్థాయికి చేరుకున్నాయి. ఇంతకుముందు మధుమేహం, గుండె జబ్బులు లేని వాళ్ళకి కూడా కోవిడ్ తర్వాత ఆ ఛాయలు ప్రస్తుతం ప్రస్ఫుటంగా కనబడుతున్నాయి.
3/8
I have been seeing a lot of younger than 40 year olds getting MI. Most have history of covid. There used to be MIs in this population in pre-covid era, but now the cases are certainly high. Many of these young patients do not have the traditional coronary risk factors.
Most angiograms in these patients are showing atherosclerotic changes apart from thrombosis. We used to think that covid promotes thrombosis and not atherosclerosis. There is no direct mechanism to suggest that it does. Previous studies demonstrated increased atherosclerosis…
Regarding mutagenicity of Molnupiravir, the initial test for any molecule is the Ames test which if negative indicates that the molecule in question has no mutagenicity. For Molnupiravir it was positive. If Ames test is positive, further tests are done for confirmation.
The in vivo MN study was negative. The Sprague-Dawley Rat Pig-α Assay was equivocal. But the conclusive test called Transgenic Rodent Assay in Big Blue Rat was unequivocally negative.