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Always a pleasure to listen to @KevinH_PhD discuss his testing of hypotheses in contributors to #obesity
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Many people remember his 14-day study of ultra processed foods (UPF) vs unprocessed foods (n=20) that found energy intake was ~500 kcal/d LESS with unprocessed meals
cell.com/cell-metabolis…
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cell.com/cell-metabolis…
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Details you might not know:
- Groups were not matched for type of sugar
- No hint of a difference in insulin sensitivity between groups based on OGTT results
- Groups were not matched for beverage amount (and implication for speed of food intake)
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- Groups were not matched for type of sugar
- No hint of a difference in insulin sensitivity between groups based on OGTT results
- Groups were not matched for beverage amount (and implication for speed of food intake)
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Follow up study found that meal eating rate (in grams/min) was actually SLOWER with UPFs (after beverages were removed), but rate of kcal/min intake was still higher because UPFs were much higher in energy density
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Another investigation into the mechanism of why UPF resulted in more kcal intake was *hyperpalatability* as defined by Fazzino et al. onlinelibrary.wiley.com/doi/10.1002/ob…
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In fact, UPFs did score higher in hyperpalatability than unprocessed foods, and this hyperpalatability mediates ~40% of the UPF effect on kcal intake
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Looking forward to the 4-arm crossover study that examines these variables (beverages, hyperpalatability) further!
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