Latest @Join_ZOE 5 May 2023
๐Ÿฆ 1,022,039 currently predicted to have symptomatic COVID in the UK
โœ๏ธWave, after wave, of infections, means more illness, hospitalisations, deaths, and impact of #LongCOVID.
๐—œ๐—บ๐—ฝ๐—ฟ๐—ผ๐˜ƒ๐—ฒ ๐—ถ๐—ป๐—ณ๐—ฒ๐—ฐ๐˜๐—ถ๐—ผ๐—ป ๐—ฝ๐—ฟ๐—ฒ๐˜ƒ๐—ฒ๐—ป๐˜๐—ถ๐—ผ๐—ป ๐—ฎ๐—ป๐—ฑ ๐—ฐ๐—ผ๐—ป๐˜๐—ฟ๐—ผ๐—น. Image
'Variation' is key to the #SARSCoV2 'waves', observes @MackayIM ๐Ÿ‡ฆ๐Ÿ‡บ
'Each peak of a โ€˜waveโ€™ (a new epidemic).'
โ”Likely that new COVID-19 waves, and hospitalisations, are driven and dominated by a genetically different variant of the virus called #SARSCoV2.
'๐—ฉ๐—ถ๐—ฟ๐˜‚๐˜€๐—ฒ๐˜€ adapting to the situation, through selection and expansion of ๐˜ƒ๐—ฎ๐—ฟ๐—ถ๐—ฎ๐—ป๐˜๐˜€' - in response to our immune systemโ€™s pressure on their evolution - has been the one constant driver of every wave in ๐Ÿ‡ฆ๐Ÿ‡บ, and probably everywhere...' @MackayIM
'COVID-19 no longer constitutes a public health emergency of international concern, #PHEIC.' @WHO
@DrTedros 'The number of weekly reported deaths and hospitalizations continue to decrease, but expressed concern that surveillance reporting to WHO has declined significantly'. 5 May Image

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More from @JoePajak

May 9
'๐—ฉ๐—ฒ๐—ป๐˜๐—ถ๐—น๐—ฎ๐˜๐—ถ๐—ผ๐—ป* is an important line of defence for infection control in the healthcare environment.' @NHSEngland
โœ๏ธ1,077,993 people currently predicted to have symptomatic COVID in the UK: report @Join_ZOE 9 May 2023.
Healthcare settings to note:
england.nhs.uk/long-read/applโ€ฆ Image
โœ๏ธImportant notice for healthcare settings:
'Application of #HEPA filter devices for air cleaning in healthcare spaces: guidance and standards.'
โœ๏ธVentilation* is an important line of defence for infection control in the healthcare environment. @NHSEngland
england.nhs.uk/long-read/applโ€ฆ Image
The current focus on #๐—ฉ๐—ฒ๐—ป๐˜๐—ถ๐—น๐—ฎ๐˜๐—ถ๐—ผ๐—ป highlighted areas of ๐—ต๐—ถ๐—ด๐—ต ๐—ฟ๐—ถ๐˜€๐—ธ due to ๐—ฝ๐—ผ๐—ผ๐—ฟ๐—น๐˜† ๐—ฝ๐—ฒ๐—ฟ๐—ณ๐—ผ๐—ฟ๐—บ๐—ถ๐—ป๐—ด and ๐—ถ๐—ป๐—ฎ๐—ฑ๐—ฒ๐—พ๐˜‚๐—ฎ๐˜๐—ฒ ๐˜ƒ๐—ฒ๐—ป๐˜๐—ถ๐—น๐—ฎ๐˜๐—ถ๐—ผ๐—ป in ๐—ต๐—ผ๐˜€๐—ฝ๐—ถ๐˜๐—ฎ๐—น๐˜€ and other ๐—ต๐—ฒ๐—ฎ๐—น๐˜๐—ต๐—ฐ๐—ฎ๐—ฟ๐—ฒ ๐˜€๐—ฒ๐˜๐˜๐—ถ๐—ป๐—ด๐˜€. @NHSEngland
england.nhs.uk/long-read/applโ€ฆ Image
Read 19 tweets
May 7
'COVID-19 #PHEIC 'officially' over but the #pandemic will be with us for many years. Nor is it clear that govts have learned sufficiently from the outbreak to be ready to fight off new emerging microbes that could trigger worse calamities.' @RobinMcKie
theguardian.com/world/2023/mayโ€ฆ
Can't flick a switch and declare the pandemic over, especially one so damaging and of such scale.๐Ÿ’ฏ@SGriffin_Lab
Whether labelled global pandemic or not, many countries experiencing significant waves of infection, thousands dying every week.๐Ÿ’ฏ@SusanMichie
theguardian.com/world/2023/mayโ€ฆ
'This bittersweet [@WHO] announcement seems more a white flag than a cause for celebration. While there has been profound progress, this decision reflects the political reality of Covid more clearly than the medical situation.' @DrBenNeuman @TAMU_Biology

theguardian.com/world/2023/mayโ€ฆ
Read 6 tweets
May 7
#SARSCoV2 'waves':
'Viruses changing their โ€˜lookโ€™ through selection and expansion of variants in response to our immune systemโ€™s pressure on their evolution has been the one constant driver of every wave in ๐Ÿ‡ฆ๐Ÿ‡บ, and probably everywhere, so far.' @MackayIM
virologydownunder.com/variation-is-kโ€ฆ Image
'Variation is key to the #SARSCoV2 'waves':
'Each peak of a โ€˜waveโ€™ (new epidemic) of COVID-19 hospitalisations has been driven and dominated by a genetically different variant of the virus called #SARSCoV2.' @MackayIM ๐Ÿ‡ฆ๐Ÿ‡บ

virologydownunder.com/variation-is-kโ€ฆ
'COVID-19 hospitalisation & ICU peaks & troughs (= 'down to' 1,200 admissions) by month, Mar '20 to 14 Apr '23:
Predominating variants indicated at peaks. Every peak = a new variant, as one would expect, given epidemics = first & foremost driven by pathogen novelty.' @MackayIM ๐Ÿ‡ฆ๐Ÿ‡บ Image
Read 13 tweets
Apr 1
๐Ÿฆ 1,483,797 People are currently predicted to have symptomatic COVID in the UK; from @Join_ZOE Health Study reports.
Updated 1 April, 5am.
@ONS should still be providing its weekly reports, without an 'early warning' system, we are unprepared for what lies ahead.
#COVIDisAirborne
#COVID reinfection can be problematic: doi.org/10.1038/s41591โ€ฆ @NatureMedicine 'Each subsequent COVID infection increases risk of developing chronic health issues like diabetes, and organ failure...' @zalaly @BCBowe @Biostayan @AmerMedicalAssn @tweetrambod
ama-assn.org/delivering-carโ€ฆ
'Study of 5,819,264 people, [443,588 with a first infection, 40,947 with reinfection...] compared to those with no reinfection, those who had reinfection exhibited increased risks of all-cause mortality, hospitalization & several prespecified outcomes'. @zalaly @BCBowe @Biostayan
Read 11 tweets
Mar 31
โ€˜#LongCOVID is an emerging phenomenon that is not yet fully understood. These are Experimental Statistics. Estimates currently under development, and may change as scientific understanding of long COVID improves. @ONS advise caution when using the data.โ€™

ons.gov.uk/peoplepopulatiโ€ฆ
โ€˜Prevalence of ongoing symptoms following coronavirus (COVID-19) infection: 30 Mar 2023.
Estimates of the prevalence of self-reported long COVID and associated activity limitation, using UK @ONS Infection Survey data covering the 4 weeks to 5 Mar 2023.โ€™

ons.gov.uk/peoplepopulatiโ€ฆ
โ€˜Estimated 1.9 million people living in private households in the UK experiencing self-reported #LongCOVID (symptoms continuing for >4 weeks after first confirmed or suspected coronavirus (COVID-19) infection that werenโ€™t explained by something else) as of 5 Mar 2023.โ€™
HT: @ONS
Read 4 tweets
Mar 15
'Doctors have a role in tackling air pollution: hereโ€™s how some are rising to the challenge.'
@WanderingSal @bmj_latest

1/n

bmj.com/content/380/bmโ€ฆ
'UKโ€™s air quality is a public health problem, particularly for childrenโ€™s respiratory health.
Outdoor exposure to air pollution contributes to 26โ€‰000 to 38โ€‰000 deaths a year in the UK'.
@WanderingSal @bmj_latest #AirPollution
#RespiratoryHealth

2/n

bmj.com/content/380/bmโ€ฆ
'Outdoor exposure to air pollution contributes to 26,000 to 38,000 deaths a year in the UK - and has been shown to increase the risks of heart disease, heart attacks, cancer, and strokes.' @WanderingSal @bmj_latest @asthmalunguk
#AirPollution

3/n

bmj.com/content/380/bmโ€ฆ
Read 7 tweets

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