Saman Nematollahi Profile picture
Transplant ID @UAZDivID. Team member @CPSolvers and @CardioNerds. APD of ID fellowship program, Assistant Clerkship Director of IM @UAZMedTucson. Husband & Baba
3 subscribers
Aug 3, 2020 7 tweets 3 min read
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#Cryptococcal Infection in #Hematologic #Malignancies and Hematopoietic Stem Cell Transplantation

Here we review crypto with attention to its background, epi, risk factors, presentations, diagnosis, treatment, & prevention in hematologic malignancies

pubmed.ncbi.nlm.nih.gov/32740974/ 2/
At baseline, even prior to the start of immunosuppression, newly diagnosed patients with heme malignancies have cellular & humoral immune deficits with functional and absolute defects in granulocyte and lymphocyte function
that place patients at increased risk for infections
Apr 1, 2020 19 tweets 14 min read
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Going along with @cardionerds Part 1 of 4 (Episode 24), here’s some info regarding #COVID19 treatment

cardionerds.com/episodes/covid… 2/
In your opinion, which medication will be most effective for #SARSCoV2/#COVID19?
Jan 31, 2020 19 tweets 16 min read
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Growing up in Tucson and going to med school @UAZMedTucson, I thought I knew a lot about #coccidioidomycosis. Definitely not!

Here we discuss history, epidemiology, ecology, some cool facts about #Cocci, and reasons why #fluconazole may not be the best drug for Cocci. 2/
In 1892 in Argentina, Alejandro Posadas wrote the first report of a pt w/ disseminated cutaneous cocci

Shortly after, a laborer in San Joaquin valley also had skin lesions

Skin biopsies of both pts revealed protozoa-like orgs, similar to Coccidia

academic.oup.com/cid/article/44…
Jan 1, 2020 16 tweets 8 min read
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Let's start off 2020 with some #Bacteremia myth💥!!

Some questions answered here:
Do fevers predict bacteremia?

Can you predict when someone will have an ESBL bacteremia?

I learned a lot preparing this review, I hope you do too

#MedTwitter #IDTwitter #MedEd 2/
Is it normal for people to be bacteremic on a daily basis?
Nov 28, 2019 18 tweets 18 min read
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I bet you are wondering, what's all the fuss with #candidemia? Why do we care? How to diagnose? How to treat?

Get ready for a thanksgiving treat!

Inspired by @DxRxEdu 2/

In the US, invasive candidiasis is the most common fungal infection in hospitalized patients (4th most common infection overall)

1. C. diff
2. Staph aureus
3. E. Coli
4. Candida

www-nejm-org.proxy1.library.jhu.edu/doi/pdf/10.105…
Nov 7, 2019 14 tweets 11 min read
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Hi hi hi. We see lots of red flags on a daily basis when we review labs.

One thing we see commonly is #lymphopenia. Should we care? When can we dismiss it and when should we work it up?

Let’s find out.

#MedEd #MedTwitter #IDTwitter #Tweetorial #oncology 2/
- Lymphopenia assc w/ ⬆️risk of sepsis
- More common in elderly and w/ co-morbidities
- lymphs account for 20-40% of WBC, may go unnoticed when WBC checked w/o diff
- Primary- recurrent infxns in kids, CVID in adults
- Secondary-⬇️production; ⬆️destruction; hiding in tissue
Oct 22, 2019 18 tweets 7 min read
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Have you ever wondered about the testing characteristics of the #Histoplasma antigen? We order them all the time, but how good are they? Come, let's explore together!
#Histoplasmosis #IDTwitter #MedEd 2/
First, let's discuss distribution and some background information. We shouldn't say that Histo is an endemic mycosis given its worldwide distribution. Factors that influence this include #ClimateChange and #Deforestation.
ncbi.nlm.nih.gov/pubmed/26897068
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