Alessio Bricca Profile picture
PhD in Health Sciences | Assistant Professor | @MobilizeDk @FoF_research @PROgrezDK @SyddanskUni | #exercise #MSK #multimorbidity 🇮🇹🇩🇰🇪🇺
Feb 21 10 tweets 3 min read
The molecular mechanisms of exercise on tissue regeneration on the musculoskeletal, cardiovascular, and nervous system.

Discover the science behind 🏃‍♂️

🧵 Image ❤️ Heart

Exercise induces physiological hypertrophy of left ventricle and reduction of myocardial infarction area by promoting the proliferation of cardiomyocytes. Image
Jan 10 8 tweets 3 min read
Physical inactivity is a concern.

Understanding the motivators & barriers for #physicalactivity is crucial for effective lifestyle campaigns.

There is no one-size-fits-all solution but key recommendations include addressing fears, understanding individual preferences and...

🧵 Image 🔍 This thread is based on a systematic review that included 44 articles involving 28,583 subjects.

They identified a total of 61 motivators and 59 barriers for physical activity!

These included...

sciencedirect.com/science/articl…
Jan 5 12 tweets 4 min read
OSTEOARTHRITIS

Osteoarthritis is degenerative joint disease that leads to pain, stiffness and loss of function.

These are the latest insights into the pathogenesis and management of osteoarthritis.

🧵 https://www.nature.com/collections/jhgadjhbbd @ArthritisFdn @arthritis_care @ArthritisSoc @ArthritisDigest In OA trials, understanding and managing 'placebo responses' is crucial.

To improve OA clinical trials, we need to grasp placebo responses, identify responders, and leverage insights for better outcomes.

Utilising placebo effects could enhance OA symptom management. https://www.nature.com/articles/s41584-023-01021-4
Jan 1 10 tweets 3 min read
🏋️‍♀️ Exercise is mitochondrial medicine for muscle 💪

Let's dive into the fascinating world of mitochondria – the energy hubs that keep our #muscles going strong!🔋

Spoiler alert: #Exercise is a game-changer in tackling mitochondrial glitches, even without key regulators! 🏃‍♀️

🧵 https://www.sciencedirect.com/science/article/pii/S2666337619300083#bib94 2/10 With about 1200 proteins in their matrix, membranes, and intermembrane spaces, these unique organelles play a crucial role in generating ATP for cell survival. ⚡️

academic.oup.com/nar/article/44…
Oct 25, 2023 10 tweets 3 min read
🦵 Knee Troubles? Here's what you need to know!

🧵

#knee #pain #exercise #surgery #education #injections #orthosis #diet #osteoarthritis #arthroplasty https://pubmed.ncbi.nlm.nih.gov/37874571/ 2/10: #Knee #osteoarthritis (OA) is a common condition affecting around 654 million people globally

It's the likely diagnosis for knee #pain in those aged 45 or older with activity-related knee pain and little morning #stiffness
Aug 6, 2023 10 tweets 3 min read
Educate your patients about the importance of muscle strength 🦵

Prevent #sarcopenia by building muscle in youth and maintaining it in middle age to reduce muscle loss as we age.

BUT it is never too late to benefit from improving muscle strength.

Here's why👇

🧵Thread https://pubmed.ncbi.nlm.nih.gov/30312372/ 2/10: 🏋️ Muscle strength declines during adulthood and in later life.

After reaching the age of 50 years, people may experience a decline in leg muscle mass (1–2% per year) and strength (1.5–5% per year).

pubmed.ncbi.nlm.nih.gov/24596700/
Jul 26, 2023 10 tweets 4 min read
Capability, Opportunity & Motivation

The three essential elements that must be in place for any person to engage in #PhysicalActivity #Exercise #ExerciseTherapy 🚶🚶‍♀️

Let's see why...

🧵Thread

https://t.co/gYXNhRZKOSqeios.com/read/WW04E6.2
Image 2/10: #PhysicalActivity #Exercise #ExerciseTherapy are terms that mean slightly different concepts

Let's not confuse them 👇

https://t.co/aDpwdUK3dlpubmed.ncbi.nlm.nih.gov/3920711/
Image
Jul 20, 2023 10 tweets 3 min read
🧬Your genes are not your fate🧬

Clinicians, educators, and public health professionals, spread the word:

#PhysicalActivity is vital for T2D prevention, even if your genes suggest otherwise! 🩺🗣️

Let's see why...

🧵Thread



#prevention pubmed.ncbi.nlm.nih.gov/37277158/
Image 2/10: "🌍 #Diabetes affects over 10% of the world's population and we all know the complications!

T2D is common due to #genetics #obesity #diet & #PhysicalActivity BUT how does genetic risk and physical activity interact in the onset of T2D?

medicinejournal.co.uk/article/S1357-…
Jul 3, 2023 10 tweets 3 min read
The history of “Exercise Is Medicine” in ancient civilizations.

👉Embark on a two-millennium journey to draw wisdom from the past to enhance the future 👈

🧵Thread



#exercisetherapy https://t.co/IUNzgtGXgKncbi.nlm.nih.gov/pmc/articles/P…
Image 2/10: 🌍Susruta of India was the first “recorded” physician to prescribe exercise for his patients but not too little & not too much.

“it should be taken every day” but taken “only to half extent of his capacity” as otherwise “it may prove fatal” Image
Jul 2, 2023 10 tweets 4 min read
Adding 10 minutes per day of moderate-to-vigorous physical activity resulted in an estimated 111 174 preventable deaths per year.

But there is more you need to know...

🧵Thread



#physicalactivity #Health #healthcare https://t.co/VlLmVQzsDIjamanetwork.com/journals/jamai…
2/10: Moderate-to-vigorous physical activity (MVPA) refers to a level of physical activity that goes beyond light-intensity activities and requires a moderate or high level of effort.
May 24, 2023 10 tweets 4 min read
Frailty is not a contraindication to prescribe exercise therapy, but rather one of the most important reasons to prescribe it.

🛑A message worth spreading 🛑

🧵Thread

#exercise #PhysicalActivity #geriatricians #olderadults

Ref: sciencedirect.com/science/articl… Image 2/10: Building resilience for optimal ageing and the crucial role of physical activity and healthy behaviours. Image
May 23, 2023 8 tweets 3 min read
Will a pill 💊ever be able to mimic the effects of #exercise ?🏃

Short answer: Probably NO

Here's why👇

🧵Thread

Ref: nature.com/articles/s4157… Image 2/8
Exercise is effective in the primary prevention of at least 35 chronic conditions.

onlinelibrary.wiley.com/doi/full/10.11…
May 11, 2023 10 tweets 3 min read
The anti-inflammatory effects of #exercise: mechanisms and implications for the prevention and treatment of disease 🧵

nature.com/articles/nri30… Image 2. Physical inactivity is linked to various health problems like #type2diabetes, #heartdisease, #cancer, and more. This is partly because of the accumulation of visceral fat, which triggers #inflammation in the body and promotes the development of these diseases.