Thread Reader helps you read and share Twitter threads easily!
I'm @ThreadReaderApp a Twitter bot here to help you read threads more easily. To trigger me, you just have to reply to (or quote) any tweet of the thread you want to unroll and mention me with the "unroll" keyword and I'll send you a link back on Twitter 😀
— Thread Reader App (@threadreaderapp) November 25, 2017
X thread is series of posts by the same author connected with a line!
From any post in the thread, mention us with a keyword "unroll"
@threadreaderapp unroll
Follow @ThreadReaderApp to mention us easily!
Practice here first or read more on our help page!
Recent
All Star Wars Opening Crawls and Scenes (1 to 9) via @YouTube
"#Lifterature?"
"#SomeIsSelfParody?"
My statin thread hit over 400k + views yesterday. Thousands of you asked the same question. “What about Repatha?” Here is the answer. It is a bomb shell. You better sit down.
I remember sitting on my bathroom floor with a needle in my hand.
My cardiologist told me Lipitor was the answer. 80mg. Within months I started losing my memory. Words disappeared mid-sentence. I could not remember my daughter's phone number.
He switched me to Crestor. Same thing.
Then he told me the future had arrived. A new drug called Repatha. A PCSK9 inhibitor. $14,000 a year. An injection I had to give myself every two weeks.
I sat on the cold tile of my bathroom floor, pushed a needle into my own stomach, and injected a foreign substance into my body because a doctor told me a number on a lab report was going to kill me.
That was the lowest point of my life.
What I did not know yet is what the data actually said about the drug I was injecting.
🧵
I remember sitting on my bathroom floor with a needle in my hand.
My cardiologist told me Lipitor was the answer. 80mg. Within months I started losing my memory. Words disappeared mid-sentence. I could not remember my daughter's phone number.
He switched me to Crestor. Same thing.
Then he told me the future had arrived. A new drug called Repatha. A PCSK9 inhibitor. $14,000 a year. An injection I had to give myself every two weeks.
I sat on the cold tile of my bathroom floor, pushed a needle into my own stomach, and injected a foreign substance into my body because a doctor told me a number on a lab report was going to kill me.
That was the lowest point of my life.
What I did not know yet is what the data actually said about the drug I was injecting.
🧵
The FOURIER trial was the largest study ever conducted on Repatha. 27,564 patients. Published in the New England Journal of Medicine.
The drug crushed LDL cholesterol by 59%. The press release said it reduced cardiovascular events by 15%. Doctors celebrated. Amgen's stock price soared.
Then in 2022 independent researchers obtained the original clinical study report from European and US regulators. What they found should have made front page news. It did not.
There were significant inconsistencies between the raw trial data and what was published.
After readjudication:
113 cardiac deaths on Repatha.
88 cardiac deaths on placebo.
28% more people died of cardiac causes on the drug than on nothing.
The drug I was injecting into my body on my bathroom floor had more cardiac deaths than a sugar pill.
Nobody told me. Nobody told any of us.
The drug crushed LDL cholesterol by 59%. The press release said it reduced cardiovascular events by 15%. Doctors celebrated. Amgen's stock price soared.
Then in 2022 independent researchers obtained the original clinical study report from European and US regulators. What they found should have made front page news. It did not.
There were significant inconsistencies between the raw trial data and what was published.
After readjudication:
113 cardiac deaths on Repatha.
88 cardiac deaths on placebo.
28% more people died of cardiac causes on the drug than on nothing.
The drug I was injecting into my body on my bathroom floor had more cardiac deaths than a sugar pill.
Nobody told me. Nobody told any of us.
This is not the first time a cholesterol drug killed more people than it saved.
In 2006 Pfizer ran the ILLUMINATE trial on torcetrapib. 15,067 patients. The drug raised HDL by 72% and lowered LDL by 25%. On paper it was perfect.
82 deaths in the drug group. 51 on placebo. A 58% increase in mortality.
Pfizer's CEO called it "one of the most important compounds of our generation." Two days later they pulled it and told every patient to stop immediately.
In 2006 Pfizer ran the ILLUMINATE trial on torcetrapib. 15,067 patients. The drug raised HDL by 72% and lowered LDL by 25%. On paper it was perfect.
82 deaths in the drug group. 51 on placebo. A 58% increase in mortality.
Pfizer's CEO called it "one of the most important compounds of our generation." Two days later they pulled it and told every patient to stop immediately.
Q-Line Biotech SME IPO opens today.
I recently visited their Lucknow manufacturing facility and spent time understanding the business, management and industry dynamics first-hand.
Some notes & observations from the ground 👇(1/10)
I recently visited their Lucknow manufacturing facility and spent time understanding the business, management and industry dynamics first-hand.
Some notes & observations from the ground 👇(1/10)
1/ Q-Line operates in the IVD (In Vitro Diagnostics) space — basically machines & reagents used in pathology labs.
Strong presence in Clinical Chemistry & Hematology with meaningful market share in India’s reagent market.
(2/10)
Strong presence in Clinical Chemistry & Hematology with meaningful market share in India’s reagent market.
(2/10)
2/ A large part of the business currently comes from UP government hospital labs via promoter-linked POCT Group.
POCT handles end-to-end diagnostics operations while Q-Line supplies machines/reagents.
Overall group scale:
• POCT ~₹650 Cr
• Q-Line ~₹320 Cr
• Heidelco ~₹100 Cr
So, a big UP based healthcare group. (3/10)
POCT handles end-to-end diagnostics operations while Q-Line supplies machines/reagents.
Overall group scale:
• POCT ~₹650 Cr
• Q-Line ~₹320 Cr
• Heidelco ~₹100 Cr
So, a big UP based healthcare group. (3/10)
Claude/ChatGPT pays me over $6,247 per month.
And no, I don't work for them.
I just use 2 insanely powerful prompts ↓
And no, I don't work for them.
I just use 2 insanely powerful prompts ↓
Access the Amazon website
Next, go to the electronics category and filter all products that are sold for more than $100:
Next, go to the electronics category and filter all products that are sold for more than $100:
Go to ChatGPT
Once you've selected your product, ask ChatGPT to provide you with positive and negative product reviews:
ChatGPT will optimize your time by listing all the reviews it has found on your product, so you don't have to spend hours doing it yourself.
Once you've selected your product, ask ChatGPT to provide you with positive and negative product reviews:
ChatGPT will optimize your time by listing all the reviews it has found on your product, so you don't have to spend hours doing it yourself.
Your Chrome is eating 8GB of RAM right now.
If your laptop fan sounds like a jet engine and Chrome freezes every 5 minutes, this is for you.
10 settings that reclaimed 6GB of RAM on my machine.
Steal them 👇
If your laptop fan sounds like a jet engine and Chrome freezes every 5 minutes, this is for you.
10 settings that reclaimed 6GB of RAM on my machine.
Steal them 👇
1. Turn on Memory Saver (the setting Google hid from you)
- Open Chrome → 3 dots (top right) → Settings
- Click "Performance" in the left sidebar
- Toggle ON "Memory Saver"
- Set mode to "Moderate" or "Maximum"
Chrome auto-frees memory from inactive tabs while keeping them visible. Tabs reload instantly when you click back.
This alone can free 4-6GB.
- Open Chrome → 3 dots (top right) → Settings
- Click "Performance" in the left sidebar
- Toggle ON "Memory Saver"
- Set mode to "Moderate" or "Maximum"
Chrome auto-frees memory from inactive tabs while keeping them visible. Tabs reload instantly when you click back.
This alone can free 4-6GB.
2. Audit your extensions (the silent RAM killers)
- Type chrome://extensions in the address bar
- Look at every single one
- Used it in the last 30 days? Keep it
- If not → Remove
Each extension eats 50-200MB in the background.
Most people have 15+ extensions. That's 1-3GB gone before you open a single tab.
- Type chrome://extensions in the address bar
- Look at every single one
- Used it in the last 30 days? Keep it
- If not → Remove
Each extension eats 50-200MB in the background.
Most people have 15+ extensions. That's 1-3GB gone before you open a single tab.
A man was promised Jannah again and again.
Not because he prayed all night.
Not because he fasted every day.
Not because he gave the most charity.
Even the companions wondered:
What was the deed that made him so special?
Not because he prayed all night.
Not because he fasted every day.
Not because he gave the most charity.
Even the companions wondered:
What was the deed that made him so special?
The companions were sitting with the Prophet ﷺ
when heﷺ suddenly said:
“A man from the people of Jannah is about to enter.”
Moments later, a simple man walked in.
He entered with water still dripping from his wudu, holding his shoes in his left hand.
when heﷺ suddenly said:
“A man from the people of Jannah is about to enter.”
Moments later, a simple man walked in.
He entered with water still dripping from his wudu, holding his shoes in his left hand.
Nothing about him seemed unusual.
The next day, it happened again.
And then again on the third day.
Each time, the Prophet ﷺ said
a man from Jannah was coming -
and it was the same man.
The next day, it happened again.
And then again on the third day.
Each time, the Prophet ﷺ said
a man from Jannah was coming -
and it was the same man.
So, Abhijit Dipke of Cockroach 🪳Jannta Party is no different than this PARA SF Major, who settled with his Wife in US and tweets regularly against, whatever he wishes.
Bare minimum "Skin in game" which you can have is to have your boots on the ground for which you are fighting.
Bare minimum "Skin in game" which you can have is to have your boots on the ground for which you are fighting.
(2) We don't know when and why Mr.Abhijit Dipke, "Founding President" of Cockroach Janta Party relocated to US.
Suddenly, he would have found a lost motherly love for Madar-E-Vatan , but despite exodus of Surat Workers, NEET Paper Leak, Rapes, Bulldozers etc etc; he was waiting
Suddenly, he would have found a lost motherly love for Madar-E-Vatan , but despite exodus of Surat Workers, NEET Paper Leak, Rapes, Bulldozers etc etc; he was waiting
(3) It's not the BJP of 2012.
If you really wanted to have some minuscule credibility, of your intention of "Poorey Ghar Ko Badal Deingey", should have come back to India at least.
I mean, what does it take to register a domain and build a sorry website, 5 mins.
SM Expert.
If you really wanted to have some minuscule credibility, of your intention of "Poorey Ghar Ko Badal Deingey", should have come back to India at least.
I mean, what does it take to register a domain and build a sorry website, 5 mins.
SM Expert.
Your Android phone probably isn’t slow because it’s old.
It’s slow because of a default setting most people never change.
And almost nobody finds this before buying a new phone.
The fix takes 90 seconds.
Here’s exactly how to speed it up ⤵️
It’s slow because of a default setting most people never change.
And almost nobody finds this before buying a new phone.
The fix takes 90 seconds.
Here’s exactly how to speed it up ⤵️
I’ve been using this trick since 2012 — back on my first Android phone.
It made a cheap single-core device feel dramatically faster.
And the crazy part?
It still works on almost every Android phone in 2026.
Most people don’t even know this setting exists.
It made a cheap single-core device feel dramatically faster.
And the crazy part?
It still works on almost every Android phone in 2026.
Most people don’t even know this setting exists.
Here’s what’s actually slowing your phone down.
Every time you open an app, switch pages, or tap a button, Android plays a small animation.
By default, those animations run at 1x speed usually around 300ms for every transition.
That tiny delay happens hundreds of times a day.
And over time, your phone starts to feel slow even when the hardware is still fine.
Every time you open an app, switch pages, or tap a button, Android plays a small animation.
By default, those animations run at 1x speed usually around 300ms for every transition.
That tiny delay happens hundreds of times a day.
And over time, your phone starts to feel slow even when the hardware is still fine.
The US electric grid hasn’t grown meaningfully in 20 years. Now data centers want to add the equivalent of three Californias to Texas alone by 2030. You can’t just plug that into existing utility ratemaking math. A new paradigm is needed. 🧵
@TKavulla describes the core problem: utility pricing recovers average embedded costs. But every new data center megawatt today costs more than average to serve — materials up 152% since 2019, capital costs rising fast. Under current rules, legacy ratepayers automatically subsidize new data center load. That’s the trap.
The Trump admin’s Ratepayer Protection Pledge (March 2026) names the right goal: AI companies pay for their own infrastructure, full stop. But a pledge isn’t a mechanism. Three mechanisms actually work: open season auctions for grid access, customer-prepaid capital, and Bring Your Own Generation madness.
1/ Continuing his review of how Ukraine is employing Palantir Technologies' platforms in its war with Russia, Belarusian-Russian journalist Alex Zimovsky breaks down in detail Palantir's capabilities and usages, according to public statements and reports. ⬇️
2/ (For a briefer summary see the linked thread below.)
3/ "Palantir's platforms (primarily Gotham for data fusion and targeting, MetaConstellation for multisensor orchestration, and their derivatives, integrated through the Brave1 Dataroom) serve as the primary "operating system of war."
1/ Russian warbloggers are increasingly admitting that Russia is suffering steady attrition from endless swarms of Ukrainian drones. '13 Tactical' posts a lament about Russia's strategic dilemma as it faces escalating costs in its war in Ukraine. ⬇️
2/ The Russian military volunteer Dmitry Tinkov, writing on the '13 Tactical' Telegram channel, reviews the current situation and is very unhappy at what he sees, but takes refuge in half-hearted bravado as the only solution that he sees:
3/ "I think there are three underlying factors at the root of all our problems:
1. Those at the top genuinely believed they could reach an agreement on our terms.
2. They don't know what to do next with Ukraine (= what the outcome should be).
1. Those at the top genuinely believed they could reach an agreement on our terms.
2. They don't know what to do next with Ukraine (= what the outcome should be).
SitRep - 20/05/26 - 20 major oil sites hit in May only
An overview of the daily events in Russia's invasion of Ukraine. Unmanned Systems Forces commander Magyar said 10 major Russian oil sites were hit in the first 20 days of May.
REPOST=appreciated
1/X
An overview of the daily events in Russia's invasion of Ukraine. Unmanned Systems Forces commander Magyar said 10 major Russian oil sites were hit in the first 20 days of May.
REPOST=appreciated
1/X
Missed the latest?
As usual we start with Russian losses
