Thread by @aakashshingada

1. @drmanishasahay talks about AKI in pregnancy at the #ISNWCN

2. Changing landscapes in PR-AKI
Rising incidence in developed countries - mainly because it increasing maternal age and comorbidities #ISNWCN

3. Pregnancy and non pregnancy causes of PR-AKI #ISNWCN

4. Peurperial sepsis commonest cause of PR-AKI and pre eclampsia in developed. however,this seems to be changing too.. with decreasing incidence of sepsis and higher incidence or pre-eclampsia associated Aki in developed countries #ISNWCN
Data from Presenter's institute.

5. Revising differentiation between traditional causes of PR-AKI #ISNWCN

6. Diagnosis of preeclampsia. Proteinuria no longer required for diagnosis.
Role of home BP in diagnosis. OPTIMUM trial is underway. #ISNWCN

7. Concept of maternal vs placental PET #ISNWCN

8. Newer therapeutics for PE #ISNWCN

9. aHUS one of the causes OF PR-AKI #ISNWCN
Eculizumab in pregnancy associated aHUS - a valid option and safe!

10. Immediate poor maternal and fetal outcomes well summarised #ISNWCN

11. 2-10% of patients with PR-AKI progress to ckd, shown across multiple populations #ISNWCN

12. PR-AKI causes 💔! Poor long term CV outcomes, increased risk of hypertension, t2dm, strokes, pvd and cad #ISNWCN

13. Poor long term fetal outcomes in mothers with PR-AKI #ISNWCN

14. Summarising salient points - nice self explanatory slide. Most important take home is to establish long term follow up and treatment #ISNWCN