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Temporal distribution of deleterious variations influences the estimation of FST biorxiv.org/content/10.110… - why most genetic differences b/w distant pop'ns are at neutral sites
This is why we can't infer much about phenotypic similarity w/in groups or diffs b/w groups from genetic similarity or distance based on profiles of SNPs, because new variants enter each pop'n all the time and have outsized phenotypic effects
It is not just that there is much more genetic variation w/in than b/w populations, it is that there is much more POTENT genetic variation w/in populations
Genetic distance alone (or genetic drift alone) is thus not expected to shift the mean of complex traits b/w pop'ns, especially ones under purifying selection
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