Thread by @_oatc_

@StephDale68 @vickyjane64 @AdrianHarrop Yes, I've used it for 20yrs & know many using it. It has a useful moderating effect in several respects, & normal mammary development🖼️ cannot take place without it. A vital metabolite is allopregnanolone, a shortage of which is associated with depression & anxiety.

@StephDale68 @vickyjane64 @AdrianHarrop 2/ As for why doctors won't prescribe it; clued-up menopause HRT specialists do, but most others, even endocrinologists are very ignorant on it - their work is mostly with diabetes. Many confuse the artificial substitutes, which don't work well for HRT purposes since their…

@StephDale68 @vickyjane64 @AdrianHarrop 3/…purpose is to affect the uterus without the practical problems of progesterone - which has to be delivered in oil so cannot be in tablets, & needs to be taken daily, so is unforgiving of a missed day.

At HBIGDA2000 (now WPATH) I was astounded to hear the leading Dutch…

@StephDale68 @vickyjane64 @AdrianHarrop 4/…endocrinologist, Prof Gooren, as the presenter of a paper if their work contradicted his finding that progesterone was useless in trans women. When I checked his papers he had only researched Provera (medroxyprogesterone) - an artificial substitute.

@StephDale68 @vickyjane64 @AdrianHarrop 5/ At Prof Green's 2009 conference on Hormone use in trans adolescents I encountered a Harley Street consultant endocrinologist, highly regarded at the time by some trans patients, who stated trans women have no progesterone receptors. All mammals have them. 🙄

@StephDale68 @vickyjane64 @AdrianHarrop 6/ The 🇺🇸 Endocrine Society guidelines incidentally use guidance written by UCSF's Dr Maddie Deutsch as their reference on breast development. She doesn't know about this, & says trans women only usually get to Tanner 2 or 3 (5 is complete) - a sure sign of lack of progesterone

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