Good news from a therapy point of view in our fight against #SARSCoV2. A novel compound called EIDD-2801 blocks SARS-CoV-2 transmission in ferrets.
One of the compound that both reduce the symptoms and the TRANSIMISSION. 1/n
One of the compound that both reduce the symptoms and the TRANSIMISSION. 1/n
How does it work? This small drug is a ribonucleoside analogue, meaning a small fake letter of the virus alphabet. Providing this fake letter blocks the machinery that allows viral replication, resulting in virus death. 2/n
Researcher infected several ferrets with Sars-Cov2, later they put them with healthy ferrets (in the same cage) with or without this new drug. 3/n
After some days of cohabitation, they check viral levels in all the animals. Surprisingly all the treated animals showed low or no viral level. Showing that
1)drug prevent symptoms
2) drug prevents transmission
4/n
1)drug prevent symptoms
2) drug prevents transmission
4/n
Take home message:
the results are extremely promising, BUT
1) sample size relatively small
2) ferrets are not human
So we are waiting for a larger randomized human study!
nature.com/articles/s4156…
the results are extremely promising, BUT
1) sample size relatively small
2) ferrets are not human
So we are waiting for a larger randomized human study!
nature.com/articles/s4156…
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@bad_scientists
@RobiVil
@mtizzoni
@gianlucac1
@EricTopol
@DarioBressanini
@marcocattaneo
@RoadMeetsFeet
@lucacozzuto
@ScaltritiLab
@vassiljieva
@CrossWordsCW
@ThManfredi
@bicidiario
@Antonio_Caramia
@luca_forconi
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