📍Outbreak of #B117 despite full vaccinations at a nursing home. 14 residents at a 🇩🇪 nursing home have tested positive for 🇬🇧 B117 variant, despite all having 2 doses of the BioNTech-Pfizer #COVID19 vaccine—last shot on Jan 25. All mild.

➡️Keep masking. dw.com/en/coronavirus…
2) This situation highlights the needs to continue to wear masks. Transmission vs protection against severe disease clearly are two different things.

Anyone refusing to mask because they say they have vaccine —remind them they still need to mask until pandemic is over! #COVID19
3) Granted, it takes 2 weeks to develop immunity, but they already had 1 dose with that lag time. And though it’s <2 weeks after 2nd dose, this highlights that protection is not complete, and even then it’s only 95% not 100%.
4) For the Pfizer vaccine, while it is still effective against the #B117 variant overall, there was one lab study last month that found lower antibody neutralization of those immunized with the Pfizer vaccine to #B117 in a lab study.
5) That said, the Gupta Lab was the result for tests run on vaccinated patients 21 days after the 1st dose, but not yet the 2nd dose. Pfizer/BioNTech’s own test after 2 full doses shows similar efficacy. That’s why we need 2 doses and waiting time.
statnews.com/2021/01/20/pfi…
6) in another study with 2 full doses, #B117 was found to be “modestly more resistant to convalescent plasma (~3 fold) and **vaccinee sera (~2 fold)**” for both Pfizer & Moderna vaccines.

This study incidentally was not done by either pharma companies.
biorxiv.org/content/10.110…

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Eric Feigl-Ding

Eric Feigl-Ding Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @DrEricDing

11 Feb
⚠️Concerning—new data shows the more contagious #B117 variant is growing so quickly in Florida—now almost 10% of all #COVID19 case. California only ~2 weeks behind. Surge of #B117 may yield April wave if vaccine rollout slow. 🧵

(Dashboard by @my_helix)
public.tableau.com/profile/helix6… Image
2) Florida on pace for early March when #B117 passes >50% & dominant. Study by @K_G_Andersen put it at ~March 9th, with ~9 day doubling time.

#B117 is 38-49% more transmissible in Florida, but 40-60% more transmissible according to UK 🇬🇧 data. Image
3) Nationwide, doubling time is ~10 days and with an estimated data it becomes >50% dominant around March 23rd. medrxiv.org/content/10.110… ImageImage
Read 21 tweets
11 Feb
CDC experts on masks:

Community mask wearing substantially reduces transmission of #SARSCoV2 in 2 ways:

📍Source control of exhalation

📍Protecting the wearer

➡️ But they are *not equal*. CDC just advised double masking.

Important explainer 🧵.
jamanetwork.com/journals/jama/… Image
2) First, masks prevent infected persons from exposing others by blocking exhalation of virus-containing droplets into the air (termed source control)—important because at least 50% or more of transmissions are from presymptomatic & asymptomatic #COVID19 cases.
3) In recent laboratory experiments, multilayer cloth masks were more effective than single-layer masks, blocking as much as 50% to 70% of exhaled small droplets and particles.2,3 In some cases, cloth masks have performed similar to surgical or procedure masks for source control.
Read 23 tweets
11 Feb
Sobering—the more infectious #B117 variant will likely become the world's dominant strain, director of 🇬🇧 genetic surveillance @CovidGenomicsUK warned—“it's going to sweep the world, in all probability", Professor Sharon Peacock told BBC. 🧵 #COVID19
mirror.co.uk/news/uk-news/u…
2) "Once we get on top of it [Covid-19] or it mutates itself out of being virulent - causing disease - then we can stop worrying about it”

“But I think, looking in the future, we're going to be doing this for years. We're still going to be doing this 10 years down the line."
3) latest from Denmark 🇩🇰 CDC, which sequences all #SARSCoV2 samples from all cases now, the % of #COVID19 now #B117 from 🇬🇧 is up to 27% of cases. Denmark CDC is right to be worried. Fast pace of replacement growth. nyheder.tv2.dk/samfund/2020-1… Image
Read 6 tweets
11 Feb
How to fold your surgical mask to create a better fit and increase personal protection, per new CDC guidelines. #COVID19 #MaskUp
2) This is now critical. CDC advises now either double masking with cloth+surgical mask, or using the above technique to create a better seal with 1 surgical mask. Here is why: 🧵
3) critical point — Masking source and receiver yields different effects. Here is why.
Read 4 tweets
11 Feb
📍Leadership: Because of growing cases of #B117 & #B1351 variants, Germany 🇩🇪 further extends its #COVID19 lockdown until March 7.

Goal: 🇩🇪 will not lift restrictions until cases down to 35 per 100k per week (~5 per 100k/day)—currently ~68/100k/week. 🧵
2) With an eye to an outbreak of the South African #B1351 variant in the Austrian region of Tyrol bordering Germany's Bavaria state, Merkel said she had conveyed her "concern" to Austrian 🇦🇹 Chancellor Sebastian Kurz on Wednesday.

thelocal.de/20210210/germa…
3) “The text (of guideline) stresses that schools and daycare centres should be "the first to gradually reopen", but that it is for individual states to decide how and when that happens.”
Read 14 tweets
11 Feb
NEBULIZER AIRBORNE OUTBREAK—
Experts say a person during Melbourne's hotel quarantine outbreak had #COVID19 & used a nebulizer—releasing up to 10,000x more aerosol particles per minutes than breathing—creating millions more aerosols to "hitch a ride". 🧵
abc.net.au/news/2021-02-1… Image
2) Victorian 🇦🇺 Government says it is investigating the possible spread of coronavirus via a nebuliser—designed to vaporise medicine and deliver a concentrated dose to the user's lungs

Experts warn a contaminated nebuliser would become a "generator of #SARSCoV2"
3) “Victoria's Chief Health Officer Brett Sutton said at least three of those were believed to be linked to the use of the nebuliser.
Experts say it is a step forward that health authorities are acknowledging the aerosol spread of SARS CoV2
Read 9 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!