BREAKING—“A new pandemic”—Germany 🇩🇪 announces strict Easter lockdown. "What we have is essentially a new pandemic," Merkel said. The new variant #B117 is "significantly more deadly, significantly more infectious."

I’ve warned a new #COVID19 wave coming.
dw.com/en/germany-imp…
2) “German federal and state leaders have agreed on a radical shutdown over the Easter holidays.
Germany is extending the current lockdown through to April 18, German Chancellor Angela Merkel announced on Tuesday.
3) “The country will enter an even stricter lockdown from April 1 to April 5, over the Easter holiday period when shops, including grocery stores, will largely have to close.
Talks between leaders of 🇩🇪’s 16 federal states and Merkel lasted until the early hours of the morning”
4) “Merkel warned that Germany needed to "break the exponential growth of the third wave" as case numbers reached levels that authorities say will overburden ICUs.

Tuesday's announcement marks a reversal from earlier when state leaders agreed to begin a cautious reopening.
5) I’m very worried about this also happening soon in the US with its own #B117 and other variants surging.
6) there is a clear upward trend across Europe.

Sidenote: Brazil looks like its cases are rising slowly. But it’s death curve rise is the steepest.
7) Unlike many other world leaders, Merkel, a scientist herself, knows that even though a curve’s increase looks slow, it is actually exponential—and can spot it in the data.
8) Merkel’s “new pandemic” quote about #B117 variant sounds eerily familiar...

oh wait...
9) It’s well know #B117 is more contagious (by 40-60% faster transmission), but it is also 64% more severe. Danish study puts #B117 with 64% higher risk of hospitalization. And this isn’t the only severity study...
10) Another UK govt report says #B117 is 30-70% more severe.
11) And another study puts #B117 at 64% (yet again) higher risk of mortality, and growing more over time perhaps.
12) Adjacent to Germany in Belgium 🇧🇪, its Prime Minister gave a sobering announcement on pediatric transmission and hospitalizations of young adults. Belgium is also inundated by #B117 (as is France).
13) Merkel’s speech on the new #B117 variant: “We basically have a new pandemic. The mutation from 🇬🇧 has taken over—it is clearly more lethal, more contagious and contagious for longer."

Germany 🇩🇪 is taking it serious. @GovRonDeSantis should too.
14) And yes, #B117 is contagious for a longer period of time. It has a much wider distribution of infectious days (red).
15) To be clear, all the major vaccines so far work for #B117 variant. Please vaccinate!

It the South Africa 🇿🇦 #B1351 variant that is the main concern. But even for that variant, J&J and Novavax have directly data to support efficacy.

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More from @DrEricDing

24 Mar
Brazil🇧🇷 #P1 variant surging in British Columbia 🇨🇦. How much?

📍92% (140/152) of all #P1 in 🇨🇦 are in BC.

📍BC 🇨🇦 has over 2x the number of #P1 than entire USA 🇺🇸 combined (61).

📍BC 🇨🇦 found more new #P1 (+30) yesterday **in 1 day than Florida has entire pandemic**. #COVID19 ImageImage
2) Is there a bad #P1 trend in BC 🇨🇦? Yes...

Keep in mind Florida (the US state with most #P1) has only had 23 cumulative cases in all. BC has had more than that for each of the last 2 days alone. Image
3) There is debate how fast transmission of #P1 variant is. But several groups estimated it is 2-2.5x more transmissible. The 2.5x estimate is from Brazil research group @obscovid19br....
Read 11 tweets
24 Mar
BREAKING—due to surging #COVID19 cases, India 🇮🇳 has frozen all major exports of AstraZeneca #COVIDVaccine made by Serum Institute of India, world’s biggest vaccine-maker, to meet domestic demand as infections rise. This will also delay supplies to COVAX.
reuters.com/article/health…
2) “COVAX has so far received 17.7 million AstraZeneca doses from the SII, of the 60.5 million doses India has shipped in total, and many countries are relying on the programme to immunise their citizens. There have been no vaccine exports from India since Thursday.”
3) “Everything else has taken a backseat, for the time being at least,” said one of the sources. Both sources had direct knowledge of the matter, but declined to be named as the discussions are not public.
Read 11 tweets
24 Mar
First study focused on long-term neurological symptoms in people not sick enough from #COVID19 to need hospitalization: found many visiting neuro clinic had >=4 neurological issues like brain fog, headaches, tingling, muscle pain & dizziness. Avg age 43.🧵 nytimes.com/2021/03/23/hea… Image
2) “We are seeing people who are really highly, highly functional individuals, used to multitasking all the time and being on top of their game, but, all of a sudden, it’s really a struggle for them,” said Dr. Igor J. Koralnik, chief of neuro-ID and global neurology. #LongCovid
3) “In the study, many experienced symptoms that fluctuated or persisted for months. Most improved over time, but there was wide variation. “Some people after 2 months are 95 percent recovered, while some people after 9 months are only 10 percent recovered,” said Dr. Koralnik.
Read 8 tweets
24 Mar
WOW—25 new cases of #P1 variant suddenly appeared in British Columbia Canada 🇨🇦!! This is the variant from Brazil 🇧🇷 that is utterly decimating the country right now—and had ransacked Manaus 🇧🇷 despite high antibodies levels previously before it hit.

BC 🇨🇦 needs to act fast!!!
3) this is also #P1 in Brazil. Got it @DrBonnieHenry? Please stop #P1 in BC 🇨🇦 ASAP. Image
Read 4 tweets
24 Mar
Let that sink in:

60% of all ICU patients in São Paulo, Brazil 🇧🇷 are now between the ages of 30-50 years old, reports @MattRiversCNN.

Bolsonaro is actively killing the next generation by destroying families. 🧵

Time to call it—“pandemicide”. #COVID19
2) Sobering day - did you know - 1 in 3 deaths from #COVID19 worldwide today—was in Brazil? It’s true.
3) We cannot turn our backs to Brazil. If we lose control of #P1, it will endanger the world. If we let Brazil collapse, it will endanger the world.

The world must act decisively to aid Brazil.
Read 16 tweets
24 Mar
Loud protests erupted across Brazil as COVID-sceptic President Bolsonaro claimed citizens would soon be able to resume “normal lives” despite soaring death toll of 3200+ today.

~1/3 of all #COVID19 deaths worldwide today were in 🇧🇷. 🧵

(HT @tomphillipsin)theguardian.com/world/2021/mar… Image
2) “Bolsonaro, whose anti-science response to coronavirus has drawn international condemnation, made a televised address to the country on Tuesday night, as Brazil suffered by far its heaviest day of losses since the outbreak began last February.”
3) ““What I see before me is a country that attaches no value to the lives of its citizens,” the scientist and broadcaster Átila Iamarino said of his government’s response.
Read 11 tweets

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