INSACOG researchers first detected B.1.617, which is now known as the Indian variant of the virus, as early as February, Ajay Parida, director of the state-run Institute of Life Sciences and a member of INSACOG, told Reuters.

reuters.com/world/asia-pac…
1 of N
INSACOG shared its findings with the health ministry’s @Director_NCDC before March 10, warning that infections could quickly increase in parts of the country. The findings were then passed on to the Indian health ministry, this person said.
2 of N
INSACOG's initial draft media statement for the health ministry included that the new Indian variant had two significant mutations, and it had been traced in 15% to 20% of samples from Maharashtra, India's worst-affected state.
3 of N
The ministry made the findings public about two weeks later, on March 24, when it issued a statement to the media that did not include the words "high concern."
4 of N
"Policy has to be based on evidence and not the other way around, I am worried that science was not taken into account to drive policy. I know where my jurisdiction stops. As scientists we provide the evidence, policymaking is the job of the government.”- Dr Shaheed Jameel
5/n
"It was highlighted very, very clearly that unless drastic measures are taken now, it will be too late to prevent the mortality which we are going to see," said Singh, referring to a meeting which took place on April 18

6 of N
“We could have done better, our science could have been given more significance,” “What we observed in whatever little way, that should have been used better. "the country’s scientific community was dejected."
-Rakesh Mishra, director of the @ccmb_csir of INSACOG
7 of N
While I am relieved that my intuition was not misplaced, it is disheartening to note that the country failed to restrict the variant to few areas.

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More from @epigiri

3 May
What is needed now?
Multiple Temporary hospitals providing TIMELY oxygen supplementation to as many people with mild respiratory distress (poor oxygen saturation) to save many lives. Otherwise, most of them go into severe distress and it becomes that much difficult to help.
1ofN
-Use any building to place beds or rapidly construct.
- Have the facilities for triage, isolation
- Oxygen saves lives, have lots of it
- Engage as many health care workers, students & volunteers. Provide them honorarium
- Have many ambulances ready to refer immediately

2 of N
Most people with severe distress will occupy ICU beds for many days. ICU beds are limited, More people with mild oxygen insufficiency will deteriorate further due to lack of oxygen & are at risk of dying. This vicious cycle has to be broken by temporary hospitals + oxygen.
3 of N
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20 Dec 20
What’s the need for external validation?
There’s no external validity without internal validity. 2 of N
Internal validity is absence or minimization of influence of any types/sources of systematic error.
3 of N
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19 Dec 20
It changes everything about what we understand, this virus is bit too much for mankind. Challenges aplenty but #Science will take us through !
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14 Dec 20
At this stage, Universal vaccination is a double edged strategy, promoted for protecting against #SARS_CoV_2 infection under EUA.

Many reasons

1. Fewer approved vaccines in stockpile, universal coverage is a myth in short term. It will induce & worsen inequities

1 of N
2. The countries will have to reserve significant $$$$ to buy vaccines for universal coverage, often more than their annual health budget.

Resources will have to be spent justifiably: it doesn’t make sense not paying salaries of health care workers but buy vaccines. 2 of N
3. (A)Safety , (B)efficacy are prerequisites. (C) Feasibility and (D) effectiveness are next steps. Having worked for polio eradication, I love vaccines. They do wonders when they pass the critical septs (A to D). For Covid19, we do not have many options with vaccines, yet 3 of N
Read 5 tweets
12 Dec 20
#NFHS5 report released by @MoHFW_INDIA . Here are some snippets
-% women having a mobile phone that they themselves use has increased from 47 to 62 in #Karnataka compared to previous survey.
-Women who are overweight or obese (BMI ≥25) has increased from 23.3 to 30.1

1 of N
Ever-married women age 18-49 years who have ever experienced spousal violence has increased from 20.6 to 44.4 %. It either means that reporting has improved or we are becoming more regressing societies. 2 of N
Breastfeeding practices are not improving and have dropped in initiation with one hour of birth. #NFHS5

@srinidhikoya et al reported from @_MAASTHI regarding the determinants and consequences of ineffective breastfeeding practices in India. 3 of N
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27 Sep 20
How India became global leader in #polioeradication efforts?

This was enabled by world class surveillance system for detecting Acute Flaccid Surveillance in India. Districts which were detecting less than expected minimum of AFP rate per unit population were strengthened. 1 of N
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There should be a revised strategy. Define number of cases/million (CPM) as a standard unit. Compare metros, urban areas & districts based on a minimum CPM. If districts are not detecting cases, review & strengthen. A huge #inequity issue for now; vulnerable suffer more. 3 of N
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