#B1617 ARRIVAL—we just now learn that the #B1617 Indian variants first arrived in NYC in April 5-11th, but retroactively reported now. It has grown in NYC, just as #P1 from Brazil 🇧🇷 also increases in %.
2) there is a ton of concern about the specific #B16172 sub lineage of #B1617, because it is even faster transmission than the already faster #B117. This was a warning this week from the U.K. 🇬🇧 govt report.
4) Some say the @GISAID data above (magenta for #B16172) is biased over reporting. But while 12 cases of #B16172 was reported in GISAID database, 19 samples were submitted to NYC’s Pandemic Lab that was #B16172. Thus, in NYC at least, it was underreported. www1.nyc.gov/assets/doh/dow…
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NEW—the faster transmission #B16172 variant will likely dethrone #B117 and become the dominant variant in 🇬🇧 “in a matter of days” and could pose unknown dangers. Since B16172 was upgraded last week by both WHO & UK, it has *doubled* in cases. 🧵#COVID19 cnbc.com/2021/05/18/cov…
2) #B16172 has now exceeded 30% of total variants. And likely to pass 50% very very soon and become dominant. The same thing happened before when #B117 replaced previous slow old strain(s).
3) I want people to consider this… Dr @larrybrilliant, who once led the eradication of smallpox off the face of the Earth 45 years ago—is worried as heck about #B16172. It’s not just me/ @chrischirp concerned… the preeminent pandemic epidemiologist in the world is worried too!!
MIXING VACCINES—New study from Spain indicates it is likely safe to have taken AstraZeneca then switch to the Pfizer vaccine for 2nd dose—found to be “highly immunogenic and safe.” Neutralization with Pfizer for second dose increased 7 fold. #COVID19 🧵 english.elpais.com/society/2021-0…
2) “The vaccinated group saw its immune response multiply by 120 a week after this second dose, while the control group’s level held steady. When the serum of the patients was mixed with samples of #SARSCoV2, the neutralizing defense response was shown to multiply by **seven**
3) “In the equivalent trials with a second dose of AstraZeneca, this response was multiplied by three.”
However, they insisted that this comparison is not an exact one as the methodologies used differed.
💡Potential RNA therapy against #SARSCoV2 infection via lipid nanoparticle delivery on horizon. Small-interfering RNAs (siRNAs) targeting the virus were screened that effectively inhibit virus by >90% either alone or in combination. #COVID19 (link below)
2) “A SARS-CoV-2 targeted siRNA-nanoparticle therapy for COVID-19”
3) “Encapsulation of siRNAs in LNPs followed by in vivo injection ➡️ robust repression of virus in the lungs and a pronounced survival advantage to treated mice. Our LNP-siRNA approaches are scalable and can be administered upon the first sign of SARS-CoV-2 infection in humans.”
2) “The CDC's announcement Thursday that fully vaccinated people largely no longer need to wear a mask has left many Americans wondering: If there are no enforcement measures, won't people just lie about their vaccination status?
3) “Public health officials admitted that the honor system will play a large role in the new rules.
"I mean, you're going to be depending on people being honest enough to say whether they were vaccinated or not and responsible enough to be wearing ... a mask," said Anthony Fauci
Pediatric warning from Singapore health minister on the new #B1617 variant, first detected in India 🇮🇳, that it appears to affect children more, says 🇸🇬 Health Minister— this is why schools are taking a more cautious approach they say. #COVID19
2) “Education Minister Chan Chun Sing said in a press conference (May 16): “We know that there are many new strains of the Covid-19–there are various new mutations and some of these mutations are much more virulent and they seem to attack younger children. todayonline.com/singapore/new-…
3) “So it is an area of concern for us, and the way we manage the situation must (be to) constantly keep abreast of such developments and pre-empt them where possible.”
The USDA has just been sued by doctors for urging Americans to go big on milk, cheese and other dairy—claiming that the Trump USDA’s 2020 dietary guidelines are looking out for the interests of the meat and dairy industries rather than health. 🧵 washingtonpost.com/business/2021/…
2) Trump’s USDA in Dec 2020 suggested that Americans consume three servings of dairy each day. The doctors allege in the federal lawsuit that the dietary guidelines contradict current scientific and medical knowledge, harming the quarter of Americans who are lactose-intolerant.
3) “But the guidelines influence school lunches in many ways. For example, for a school to offer a plant-based milk alternative, a student must present a doctor’s note about a disability.