#ChronicPain affects over 30% of people worldwide and exerts an enormous personal and economic burden.

A new @TheLancet Series on #ChronicPain presents recent findings across specialties, with implications for health care providers and patients: hubs.li/H0PgfvK0

The Series explores 3 types of pain—nociceptive, neuropathic, nociplastic—and the biopsychosocial model of pain—interactions between #chronicpain, biological, psychological, and social factors.

Read an update on burden, best practices, and new advances: hubs.li/H0Pgfv10
Nociplastic pain is a new descriptor of pain arising from abnormal pain signal processing. It applies to a range of conditions, such as fibromyalgia, that lack clear mechanisms or biomarkers—a challenge to diagnose and treat.

Learn more ➡️ hubs.li/H0Pgfv30
Neuromodulation is an expanding area of pain medicine including surgical techniques—deep brain and spinal cord stimulation.

However, their current role in practice is limited—evidence is inconsistent and often weak.

Read more here: hubs.li/H0PgfvZ0
"Chronic pain is real. It deserves to be taken more seriously. And this @TheLancet series explains why."

Read our latest Editorial—Rethinking chronic pain: hubs.li/H0PghNb0
"...the NICE guideline takes an oversimplified approach and presents chronic primary pain as a diagnosis of exclusion..."

Read a linked Comment from @Chris_Eccleston et al—Pragmatic but flawed: the NICE guideline on #ChronicPain: hubs.li/H0Pgpcf0.

• • •

Missing some Tweet in this thread? You can try to force a refresh

Keep Current with The Lancet

The Lancet Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!


Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @TheLancet

28 May
In 2019, the no. of smokers worldwide ⬆️ to 1.1 billion. Tobacco smoking caused ~8 million deaths—1 in 5 male deaths.

#GBD studies of 204 countries highlight the enormous health toll of 🚬 and authors urge all countries to do more to ⬇️ tobacco use. See hubs.ly/H0Pd0590.
89% of smokers began by age 25—evidence suggests an individual is unlikely to become a smoker if they do not start by this age.

Yet over half of countries show no progress in reducing 🚬 among 15-24-year-olds—a critical window to prevent initiation. Read hubs.li/H0Pd09f0.
Why have 🚬 control policies had little impact on young people? They may respond to policies in different ways to adults, writes @aekunst in @TheLancetPH. The solution? Centralising young people's perspectives and experiences. Read hubs.li/H0Pd0YM0.
Read 7 tweets
18 May
NEW—Emerging evidence indicates #COVID19 has distinctive pathophysiological features that set the disease apart from respiratory failure of other origins.

A new 4-part Series in @LancetRespirMed explores COVID-19: Pathophysiology of Acute Disease: hubs.li/H0NyR540
.@osuchm et al. provide a comprehensive Review of the pathophysiology and phenotypes of #COVID19. Read in @LancetRespirMed: hubs.li/H0NySMY0.
The challenges and promise of therapeutically targeting the pleiotropic cytokine interleukin-6 are considered in the 2nd & 3rd papers.

#Interleukin-6: obstacles to targeting a complex cytokine in critical illness—Oliver McElvaney et al: hubs.li/H0NyRjW0 (1/2)
Read 5 tweets
17 May
Cardiovascular disease is responsible for 35% of deaths in women yearly—yet remains:

NEW @TheLancet Commission outlines 10 recommendations to improve health outcomes for millions of women: hubs.li/H0Ns28Y0
275 million women were diagnosed with cardiovascular disease (CVD) in 2019. Acknowledging sex and gender-specific risk factors is the key to understanding #CVD in women and reducing the 🌍 burden.

Read the #LancetWomenCVD Commission: hubs.li/H0Ns28Y0
The global prevalence of cardiovascular disease in women has declined by 4.3% since 1990, but has risen in some of the world's most populated nations—🇨🇳(10%), 🇮🇩(7%), 🇮🇳(3%).

@TheLancet #LancetWomenCVD Commission provides regional recommendations: hubs.li/H0Ns28Y0
Read 5 tweets
26 Mar
Migraine affects over 1 billion people worldwide, is the 2nd leading cause of disability, and a major source of losses to the 🌍 economy—yet professional and political awareness is lacking. Read a new @TheLancet Series on #Migraine by @MessoudAshina et al. hubs.li/H0J-73-0
In 2011, migraine cost Europe an estimated €50-€111 billion. Evidence suggests primary care could meet the needs of most #migraine patients, where available. Read an overview of migraine epidemiology, global burden, and migraine care challenges. hubs.li/H0J-73-0
Migraine diagnosis is based on clinical criteria—criteria that do not capture migraine’s heterogeneity. Read about recent progress in disease characterisation, biomarkers of #migraine, and precision medicine for affected patients: hubs.li/H0J-73-0
Read 4 tweets
24 Mar
63 million lives have been saved since 2000 by global efforts to #EndTB—efforts at risk from #COVID19. Achieving @WHO's #EndTB Strategy targets requires urgent action and investment.

On #WorldTBDay, access related content from across The Lancet titles 👇
Every day, nearly 4000 people die from #tuberculosis. Although considered a public health emergency for over 25 years, only modest progress has been made.

On #WorldTBDay, explore how recent advances could revolutionise #TB control & care in this Seminar: hubs.ly/H0JPlsv0
An estimated 568,000 missing childhood #tuberculosis cases in 2019 were neither diagnosed nor adequately treated. With childhood TB cases on the rise, the case detection gap must be narrowed, writes @Esinofils, @TogunToyin, and @BeateKampmann. Read how: hubs.li/H0JPk5p0
Read 5 tweets
8 Mar
Maternal & child undernutrition remains a major health concern—the last decade saw little progress despite proven interventions & recent gains may be offset by #COVID19. A follow-up #LancetNutrition Series calls for global recommitment.

Read hubs.li/H0HRXR80
From 2005-15, nearly 5% of children had concurrent stunting & wasting in LMICs. For maternal nutrition, prevalence of undernutrition ⬇️, but anaemia & short stature remain high.

Read the #LancetNutrition Series: hubs.li/H0HRFfS0 & hubs.li/H0HRFlX0
Previously highlighted interventions continue to be effective at reducing stunting, micronutrient deficiencies & child death. Delivering nutrition interventions within the #first1000days of life if key.

Read the @LancetChildAdol Review: hubs.li/H0HRR310 #LancetNutrition
Read 4 tweets

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!