63 million lives have been saved since 2000 by global efforts to #EndTB—efforts at risk from #COVID19. Achieving @WHO's #EndTB Strategy targets requires urgent action and investment.
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Every day, nearly 4000 people die from #tuberculosis. Although considered a public health emergency for over 25 years, only modest progress has been made.
An estimated 568,000 missing childhood #tuberculosis cases in 2019 were neither diagnosed nor adequately treated. With childhood TB cases on the rise, the case detection gap must be narrowed, writes @Esinofils, @TogunToyin, and @BeateKampmann. Read how: hubs.li/H0JPk5p0
Maternal & child undernutrition remains a major health concern—the last decade saw little progress despite proven interventions & recent gains may be offset by #COVID19. A follow-up #LancetNutrition Series calls for global recommitment.
From 2005-15, nearly 5% of children had concurrent stunting & wasting in LMICs. For maternal nutrition, prevalence of undernutrition ⬇️, but anaemia & short stature remain high.
Previously highlighted interventions continue to be effective at reducing stunting, micronutrient deficiencies & child death. Delivering nutrition interventions within the #first1000days of life if key.
NEW—COVID-19 causes more severe disease than seasonal influenza, confirms a Study of French national data from over 130,000 hospitalised patients published today in @LancetRespirMed: hubs.li/H0CRd__0 (1/4)
Nearly twice as many people were admitted to hospital for COVID-19 at the height of the pandemic than were for influenza at the peak of the 2018/2019 flu season; (COVID-19, 89,530 patients vs influenza, 45,819 patients) (2/4)
The death rate among COVID-19 patients was almost three times higher (number of deaths: COVID-19 15,104/89,530 [16.9%] vs influenza 2640/45,819 [5.8%]), and a greater proportion of COVID-19 patients experienced severe illness requiring intensive care. (3/4)
Designed in 1948, the #NHS pay structure has not kept up with the changes in women’s position in society. The medical #genderpaygap in England has worsened as a result of #COVID19, and does not narrow until aged 65. Jane Dacre et al. Comment: hubs.li/H0CHQfJ0
A recent review shows that the total medical #genderpaygap in England is 24·4% for hospital doctors, 33·5% for general practitioners, and 21·4% for clinical academics.
A severe reduction in child-care provision during the #COVID19 pandemic will have disproportionately stalled the careers of women in medicine; it is likely that most accommodations to adjust to the shortage of child-care will have been made by female doctors.
NEW—First full results from interim analysis confirm that the Oxford #COVID19 vaccine is safe and efficacious against symptomatic COVID-19 disease: hubs.li/H0CcSs60 (1/6)
The vaccine protects against symptomatic disease in 70% of cases – with vaccine efficacy of 62% for those given two full doses, and of 90% in those given a half then a full dose. (2/6)
The first clinical efficacy results of the vaccine are based on a pre-specified pooled analysis of phase 3 trials in UK and Brazil (11,636 people), alongside safety data from 23,745 participants in 4 trials in the UK, Brazil and South Africa. (3/6)
NEW—Radiotherapy following prostate cancer surgery can safely be avoided for many men: finding from a prospectively planned systematic review & meta-analysis assessing results from 2153 men enrolled across 3 trials, with median follow-up of at least 5 yrs hubs.li/H0x3LxP0
NEW—Timing of radiotherapy after radical prostatectomy (RADICALS-RT): a randomised, controlled phase 3 trial hubs.li/H0x5PXH0 (Trial 1/3)
NEW—Adjuvant radiotherapy vs early salvage radiotherapy following radical prostatectomy (TROG 08.03/ANZUP RAVES): a randomised, controlled, phase 3, non-inferiority trial @TheLancetOncol (Trial 2/3) hubs.li/H0x69kT0
NEW Editorial discusses the enormous effect that #COVID19 has had on scientific publishing as well as the increased public interest in & scrutiny of research & science hubs.li/H0wwv5L0
In recognition of #PeerRevWeek20 we would like to say thank you to our reviewers for their essential role in maintaining the advancement of science and medicine through helping us to identify the most robust and impactful work #TrustInPeerReviewhubs.li/H0wB2cg0
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