📍STUNNING-Brazil’s @jairbolsonaro apparently intended to lead 🇧🇷 to herd immunity by natural infection, **whatever the consequences**. That means (w/ 1% IFR, 70% herd threshold) by definition he planned for >1.4 mil deaths!

That was the plan!🧵 #COVID19
nytimes.com/2021/05/27/opi…
2) “Here is one example. In March 2020, a social media campaign called “Brazil Can’t Stop” was launched by [Bolsonaro’s] communications unit. Urging people not to change their routines, the campaign claimed “coronavirus deaths among adults & young people are rare.”
3) “The heavily criticized campaign was eventually banned by a federal judge and largely forgotten.
Then the plot thickened. Brazil’s former communications director, Fabio Wajngarten, told the inquiry that he didn’t know “for sure” who had been responsible for the campaign…
4) “Later, stumbling over his words, he seemed to remember that his department had developed the campaign — in the spirit of experimentation, of course — which was then launched without authorization.”
5) “Spelled out this way, the effort looks shocking. But to Brazilians living under Mr. Bolsonaro’s rule it’s hardly surprising. After all, the president seemed to do everything he could to facilitate the spread of the virus….”
6) “He has spent the last year speaking and acting against all scientifically proven measures to curb the spread of the virus. Social distancing, he said, was for “idiots.” Masks were “fiction.” And vaccines can turn you into a crocodile. nytimes.com/2021/01/18/wor…
7) “Then there was the antimalarial drug hydroxychloroquine, which Mr. Bolsonaro promoted as an early treatment and miracle cure for Covid-19 — despite all scientific evidence to the contrary and the express advice of two former health ministers.
8) “During the inquiry, two different witnesses somberly confirmed that they had seen the draft of a presidential decree stipulating that the drug’s leaflet should be changed to include its use against Covid-19.
9) As reminder, HCQ does not treat or prevent #COVID19. I’ve written countless posts on this. Here is an older debunk thread 🧵
10) “It gets worse. According to both Mr. Wajngarten and Carlos Murillo, the regional manager of Pfizer, the pharmaceutical company repeatedly offered to sell its Covid-19 vaccine to Brazil’s government between August and November last year — but got no answer at all.”
11) “Considering that Brazil was one of the first countries to be approached by the company, a quick response would have secured Brazilians as many as 1.5 million doses at the end of 2020, with 17 million more in the first half of 2021.
12) “Instead, after turning down another three offers the government eventually signed a contract in March, a staggering **seven months after the first offer**. The first one million doses arrived in late April.”
13) “The rollout, as a result of the government’s negligence in securing vaccines, has been halting, with regular shortages of shots and a lack of supplies leading to delays in production.”
14) No vaccines, leadership, no end. How nation has become a global threat.

Vaccine shortages were everywhere. amp.cnn.com/cnn/2021/03/20…
15) I’ve tried to warn the world on the crisis in Brazil for many months too. Aid always came too late.

Brazil’s pandemic crisis isn’t over yet. We must stay vigilant.
16) Let this sink in… Bolsonaro’s govt didn’t order a second batch of vaccines (138 million doses) until ICUs were full… until this crisis already happened … that’s not leadership. That is pandemicide of Bolsonaro’s govt.
17) I still cry for the people of Brazil. The world mostly watched — they couldn’t send the aid because Bolsonaro’s govt for the longest time refused outside aid. I know this for a fact from sources.
18) I’ve witnessed countless Brazilians begging for help on social media. Some more direct than others.
19) I still cry every time I watch this video from Brazil by @MattRiversCNN. The world could only watch while Brazil was held gunpoint at the whim of a madman in charge.
20) I will always stand with the people of Brazil. Brazilian American epidemiologists and scientists have also been are the forefront of the world to accelerate vaccines. There are countless Americans who do care too. The world cares for you Brazil 🇧🇷even if your leader does not.
21) Bring on more protests. The world is watching. The world is praying for change for Brazil.
22) And @LulaOficial has been asking for accelerating vaccines for Brazil.
23) this will go down in the annals of history.
Bolsonaro’s name will go down as one of the worst authoritarians.

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More from @DrEricDing

4 Jun
ICE THINNING FASTER—New study conclude that Arctic sea ice is thinning twice as fast as before. Especially in key coastal regions was thinning at a rate 70% to 100% faster than previously thought (which before had used outdated data from 20 years ago).

phys.org/news/2021-06-a… Image
2) “To calculate sea ice thickness researchers used radar from the European Space Agency's CryoSat-2 satellite. By timing how long it takes for radar waves to bounce back from the ice, they can calculate the height of the ice above the water—to infer the ice's total thickness.”
3) They also found that, across all seven coastal seas, the variability in sea ice thickness from year to year increased by 58%.
Sea ice in the coastal seas typically varies from 1/2 metre to two metres thick. Increasingly, the ice in this region is not surviving the summer melt.
Read 4 tweets
4 Jun
📍Delta variant #B16172:

50-70% more transmissible

2.7x more likely to be hospitalized than #B117

“Many people could end up in hospital, 🇬🇧 NHS could be thrown into another surge.”

Says @globalhlthtwit of @IndependentSage. #COVID19 #DeltaVariant
2) Latest UK @PHE_uk assessment on #DeltaVariant #B16172:

📌Severity is now RED (previously insufficient info)

📌Vaccines is now RED with high confidence (previously moderate) Image
3) Two separate studies on hospitalization severity—one from England 🏴󠁧󠁢󠁥󠁮󠁧󠁿 and one from Scotland 🏴󠁧󠁢󠁳󠁣󠁴󠁿— both found Increased severity of #DeltaVariant #B16172

➡️ Risk of hospital admission (Hazard Ratio = 2.61 in England and HR = 2.39 in Scotland) compared to the Kent variant #B117! Image
Read 10 tweets
3 Jun
Vaccine efficacy of Pfizer-BioNTech in Denmark 🇩🇰 for >=7 days after 2 doses:

📍53% in Long Term Care Facilities
📍86% in >=65 years needing homecare
📍77% in >=85 years old
📍80% in frontline healthcare workers
📍73% with #COVID19 high risk factors.
medrxiv.org/content/10.110… Image
2) For hospitalization admissions overall, 93% efficacy with 2 doses. But 75% efficacy for hospital admissions among those living in long term care facilities. Image
3) For #COVID19 mortality, 94% efficacy with 2 doses after 7 days. For long term care facilities residents, 89% efficacy against covid mortality. 97% for >=65 needing homecare.

Also interesting 49% efficacy against all-cause mortality! Image
Read 4 tweets
3 Jun
CELL-to-CELL transmission that avoids antibodies—a new study shows that once cells are #SARSCoV2 infected, they can infect other cells in ways which are very difficult to inhibit with antibodies. Video shows how virus can move between cells. HT @sigallab.
2) So @sigallab wanted to text if antibodies against #SARSCoV2 can neutralize the virus.

Top row, with virus infection *not via cell to cell*, the more antibodies (left), the less virus leftover.

Bottom row: in cell to cell infection, antibodies made zero difference! 👀
3) The implication? Once the infection sets in, the virus can keep proliferating and transmitting cell to cell, avoiding the blood stream or wherever antibodies can access and directly neutralize the virus. #SARSCoV2 is a tricky beast.
Read 5 tweets
2 Jun
BREAKING—Victoria🇦🇺 extends lockdown. Worse, Chief health officer Brett Sutton says cases now infected in ways “not seen before”. 📌One person infected at an indoor space “2 hours after infectious case had left” &📌another case in outdoor dining.🧵#COVID19
news.com.au/national/victo…
2) “(It) was therefore a substantial period of time but they had left two hours before the next exposed individual came in who has become a case.”
“That’s in the kind of measles category of infectiousness.” ⚠️
3) “It may be on surfaces but it could absolutely be through airborne transmission as well because of that indoor setting.”
Read 16 tweets
1 Jun
Agonizing decisions for pregnant moms Brazil 🇧🇷 maternity wards as #COVID19 is killing hundreds of moms and babies—no exaggeration. “Remove baby too early and you risk them dying outside the womb, remove them too late & they die from a lack of oxygen.”😢🧵
wsj.com/articles/covid…
2) “doctors forced to deliver her baby son who was pressing up against her disease-ridden lungs.
It was too late. Ms. Souza, an otherwise healthy 30-year-old, died three weeks after the caesarean section.”
3) “She didn’t get to hold her newborn, who was whisked away for fear she would infect him, or say goodbye to her 4-year-old son.
“She was so young, I can’t make sense of it,” said her husband. “Our sons will have to grow up without the affection and protection of a mother.”
Read 10 tweets

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