The big US/Mexico trial for Novavax is in - & yep, Novavax stays top of the class (if adverse events are as low as they were in UK trial).
Up against largely Alpha variant of concern, vaccine efficacy was 90.4% (83-95) ... 1/n ir.novavax.com/news-releases/… HT @carlzimmer
Up against largely Alpha variant of concern, vaccine efficacy was 90.4% (83-95) ... 1/n ir.novavax.com/news-releases/… HT @carlzimmer
...Trial of 29,960 people
- 14 vaxed people got mild Covid-19 vs 63 in placebo;
- Moderate/severe: 0 vaxed, 14 in placebo;
- Efficacy against variants of concern or interest was 93.2% (84-97)
- High risk people (>65 or co-morbidities): 91.0% (84-95)...2/n
- 14 vaxed people got mild Covid-19 vs 63 in placebo;
- Moderate/severe: 0 vaxed, 14 in placebo;
- Efficacy against variants of concern or interest was 93.2% (84-97)
- High risk people (>65 or co-morbidities): 91.0% (84-95)...2/n
..No data on adverse events, but press release reports severe adverse events similar in vax & placebo groups.
Efficacy as high as mRNA, with lower adverse events. They report their trial for adolescents is fully recruited (2,248). Lower adverse events *really* counts for them 3/3
Efficacy as high as mRNA, with lower adverse events. They report their trial for adolescents is fully recruited (2,248). Lower adverse events *really* counts for them 3/3
...Figures on adverse events from US/Mexico Novavax trial in a fact sheet: cdn.filestackcontent.com/fRM9l0gjQmKfUr…
Similar to the UK trial. For comparison on fatigue (highest systemic reaction, most reactive dose):
- Moderna 65%
- AZ 62%
- BNT-Pfizer 56%
- Novavax, just over 40%
HT @GinnyLouNW
Similar to the UK trial. For comparison on fatigue (highest systemic reaction, most reactive dose):
- Moderna 65%
- AZ 62%
- BNT-Pfizer 56%
- Novavax, just over 40%
HT @GinnyLouNW
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