Over 500 fully vaccinated tested positive for #COVID19 in Massachusetts in <3 weeks. As of June 5, 3,641 cases among ~3.5 mil fully vaccinated in MA–likely undercount due to lower testing in vaccinated. Yet CDC stopped counting unless hospitalized/dead🧵
nbcboston.com/news/local/mor…
2) According to the U.S. Centers for Disease Control and Prevention, a total of 10,262 breakthrough infections were reported throughout the country as of April 30, at which time 101 million people had been vaccinated.
3) More cases have likely gone unreported, federal officials have said, because they only have data from 46 states and territories. Additionally, most vaccinated people don't show symptoms that are serious enough to get tested.
4) "Testing to identify current infection remains critical to control of COVID-19," Dept of Public Health said. "People with current infection can spread the virus to others and isolation of cases and identification of close contacts is a foundation of public health response."
5) In fact, the more contagious Delta COVID-19 variant, first identified in India, has been in Massachusetts for weeks now and is steadily rising. Experts say the #DeltaVariant is more contagious and associated with a higher risk of hospitalization than the original #COVID19.
6) Think the CDC wouldn’t muzzle / stop tracking most breakthrough infections? Oh yes that exactly what the CDC did starting May 1st! They suddenly changed their tracked and stopped recording breakthroughs unless you died or landed in a hospital. Bad.

nytimes.com/2021/05/25/hea…
7) “Julie Cohn was fully vaccinated when she went to cheer at her 12-year-old son’s basketball game in March. Midway through the match, he asked to remove his mask because he was getting so hot. She thought little of it.
Three days later, he had a sore throat…
8) “He tested positive for the coronavirus, as did his younger brother a few days later. Ms. Cohn cared for them, thinking she was protected, but she woke up with what seemed like a head cold on March 28. The next day, she, too, tested positive.”
9) “Earlier this year, the agency was monitoring all cases. Through the end of April, when some 101 million Americans had been vaccinated, the C.D.C. had received 10,262 reports of breakthrough infections from 46 states/territories— “a substantial undercount,” says a CDC report
10) Genomic sequencing could be done on only 555, or about 5 percent, of the reported breakthrough cases. Over half of them involved so-called variants of concern, including the B.1.1.7 and B.1.351 variants.
Some 995 people were known to have been hospitalized.

➡️stay vigilant.

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More from @DrEricDing

18 Jun
I cry for South America—Paraguay, Suriname, Argentina, Uruguay, Colombia, Brazil & Peru are suffering a silent decimation by #COVID19 unlike anywhere else. Even in 7th-placed Peru, deaths per million is 9.12–more than 3x India. Countless families lost. 😢
theguardian.com/global-develop… Image
2) “There’s really so little support from the government – it’s a disaster. They should have prepared for all this from the start of the pandemic.”
As she spoke, two women collapsed in the hospital’s entrance, uncontrollable tears announcing another coronavirus death in Paraguay.
3) “We needed intensive care yesterday for my dad and there wasn’t any. There just isn’t any.”
On Wednesday this week, Paraguay registered 18.09 deaths per million, compared with 2.71 in India, 2.2 in South Africa, 1.01 in the US, and 0.14 in the UK.
Read 5 tweets
18 Jun
Not good—a #COVID19 outbreak kills 2 staffers in @ManateeGov Florida & hospitalized 3 others, forcing closure of building. 1 of 4 hospitalized staff died. 1 other died at home just 1 day after doctor visit. All were “non-elderly” staff.🧵
bradenton.com/news/coronavir… Image
2) Unclear vaccination status — “One staffer in the department who worked closely with the other five and didn’t contract the coronavirus was vaccinated. All five who contracted the virus had a sore throat as their initial primary complaint.”
3) “Both staffers who have died, a man and a woman, were in their 50’s. Those who were hospitalized were as young as their late 30’s, according to Hopes, causing him concern that we could be seeing one of the stronger variants in these cases.”
Read 6 tweets
18 Jun
Over 350 medical workers have caught #COVID19 in Java, Indonesia 🇮🇩despite being vaccinated with Sinovac’s CoronaVac—dozens of HCW even hospitalized, officials say, as concerns grow on vaccine efficacy versus #DeltaVariant, believed to be driving cases.🧵
reuters.com/world/asia-pac… Image
2) Most of the workers were asymptomatic and self-isolating at home, said Badai Ismoyo, head of the health office in the district of Kudus in central Java, but dozens were in hospital with high fevers and falling oxygen-saturation levels.
3) Kudus, which has about 5,000 healthcare workers, is battling an outbreak believed to be driven by the more transmissible Delta variant, which has raised its bed occupancy rates above 90%.
Read 9 tweets
18 Jun
📍SLOW ACTION ENDANGERS HEALTH & ECONOMY—Why does an epidemic take hold? #DeltaVariant surging—but what if the CDC had warned or acted earlier? Epidemiologists say we can likely prevent a big outbreak if just a cases, but harder if hundreds or 1000’s of cases… thread 🧵 #COVID19 Image
2) And early fast action buys us precious time for vaccinations if we acted fast. Even if spread was inevitable, we could prevent the worst of it if we bought ourselves more time to fully vaccinate and prepare for the #delt Image
3) In terms of travel restrictions, we all acted much too late— epidemiologists and experts were warning about India in early April already. Yet govts didn’t act until mostly late April. One major country’s CDC didn’t act until May. 👀 Image
Read 7 tweets
17 Jun
⚠️Confirmed—#DeltaVariant is by far the *most contagious** variant found to date, with a transmissibility that is ~2x faster than older strain. #P1 is 2nd fastest, says @WHO study.🧵

📍#B117 #Alpha—29% faster

📍#B1351 #Beta—25%

📍#P1 #Gamma—38%

📍#B16172 #Delta—97% #COVID19
2) “Effective reproduction number of SARS-CoV-2 variants of concern/interest compared against each other, 64 countries, data until 3 June 2021”
eurosurveillance.org/content/10.280…
3) “Of the six variants currently designated as VOI, five were considered in our analysis and among these, only B.1.617.1 (#Kappa) and B.1.525 #Eta demonstrated a statistically significant increase in the effective reproduction number of 48% and 29%, respectively.”
Read 24 tweets
17 Jun
Top question asked right now: what to do about J&J 1-shot #COVID19 vaccine & rise of #DeltaVariant? Not medical advice: lots of immunologists are hypothesizing & predicting mixing vaccines of different types could yield equal/better response. Trials TBD.🧵
bloombergquint.com/coronavirus-ou…
2) “If you can mix and match, it’s going to look better, something that immunologists have known for decades” said Danny Altmann, professor of immunology. “I’d bet my house on working hypothesis that it’s doable and would produce immunity that’s at least as good if not better.”
3) “After years of reading research on mixing vaccine types -- known as heterologous prime-boosting -- Morgon concluded that getting one dose of the AstraZeneca shot, and another from Moderna Inc.’s or Pfizer Inc.’s newer messenger RNA technology would pack the most punch.”
Read 9 tweets

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