This study looked at people coming to give birth at St George's hospital in London between March 1st and July 4th 2021.
141 had had at least one dose of a COVID vaccine
1187 were unvaccinated. 2/
(And for those always on the hunt for data about the AstraZeneca vaccine in pregnancy... 13 of the vaccinated people had had AZ.) 3/
The authors took 133 of the ppl who had had COVID vaccine and matched them (for age, ethnicity, measures of deprivation, antenatal medication and pre-pregnancy diabetes) with 399 ppl who were not vaccinated.
(8 of the vaccinated ppl were left out because they had no match). 4/
They found no difference in
👉🏻stillbirth
👉🏻fetal abnormalities
👉🏻small for gestational age
👉🏻maternal or neonatal intensive care admission
👉🏻birth < 40 weeks
between the vaccinated and unvaccinated groups. 5/
It's only mostly good news, because it means I have had to update my single slide summary *already*! 😉
6/6
PS. I would really like to thank author of this paper @kalafaterkan_md for sending it to me when it was hot off the press!
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After I wrote this thread about the potential effects of COVID vaccination in pregnancy and the lack of such effects in other vaccines, perinatal epidemilogist @deshaynef got in touch to tell me about some work she has done in this area... 🧵
Let’s start by looking at the effects at birth. We now have four large datasets from three countries telling us that babies born after vaccination in pregnancy are normal. 2/
Lots of ppl are asking about this article in the Daily Mail. The headline implies we have no idea if the Moderna #COVID19#vaccine is safe in #pregnancy, despite 1000's having had it.
We actually know that it's safe *because* 1000's have had it... 🧵
Pregnant people were not included in the first rounds of the clinical trials. However, following good safety and efficacy results in the first rounds, both Pfizer and Janssen quickly extended their trials into this group. 2/
Pfizer's trial in pregnant people started in February, and Janssen's in March, both without much fanfare. This is simply Moderna following suit. 3/
*But first* I would like to make it really clear that almost all miscarriages happen because there was something wrong with the baby that made it unviable. 1/
You cannot avoid miscarriage by being a "more careful mom" and to suggest to someone who has had a miscarriage that they should have been more careful is just cruel. 2/