On holiday without much in the way of internet, but wow! My notifications blew up when I hit some WiFi this afternoon. A few points on this… 1/
First, I’m surprised neither of them checked our national guidance, which is set out in detail for medical professionals here… 2/

assets.publishing.service.gov.uk/government/upl…
Or the guidance from @RCObsGyn and @MidwivesRCM, which makes a clear recommendation that #pregnant people get the #COVID19 #vaccine. You can find it here… 3/

rcog.org.uk/en/guidelines-…
The reason that the guidance has changed over time is both because we now have stronger evidence that COVID infection is dangerous in pregnancy, associated with increased risk of preterm birth, stillbirth and baby needing intensive care… 4/

bmj.com/content/370/bm…
… *and* because of the mounting evidence on the safety of #COVID19 #vaccines in #pregnancy. Too much too summarise in a single tweet, but data on >40k pregnant people from 4 countries, across 7 studies. Links to studies here… 5/

drive.google.com/file/d/1_wHIYX…
Finally, this question about long-term effects is one I am often asked, and it’s a fair one. But we have every reason to believe that, like other non-live vaccines given in pregnancy, there will be no (bad) long-term effects from this vaccine. Whereas there can be from COVID. 6/
Finally, I would like to call on anyone in the media who wants to interview someone about this issue to do the responsible thing and invite someone from @RCObsGyn or @MidwivesRCM, who know the data and science on this, rather than just stopping the Rolodex at random. 7/7

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Viki Male

Viki Male Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @VikiLovesFACS

8 Sep
This study looked at the effectiveness of the Pfizer #COVID19 #vaccine in #pregnancy.

👉🏻 96% effective vs. any infection

👉🏻 97% effective vs. symptomatic infection

👉🏻 89% effective vs. hospitalisation

1/

nature.com/articles/s4159…
A few additional points…

Why is effectiveness vs hospitalisation lower than against all infection? This is the opposite of what we see in larger studies of the whole population, eg. this PHE data… 2/

media.tghn.org/articles/Effec…
Very few people were hospitalised (5/10,861 in the unvaccinated group compared to 0/10,861 in the vaccinated group).

This means the confidence interval for effectiveness vs hospitalisation was wide (43 - 100%) which is likely to have lowered the central estimate. 3/
Read 6 tweets
13 Aug
New data from the V-safe pregnancy registry on the safety of #COVID19 #vaccines in #pregnancy!

👉🏻 2456 people vaccinated before 20 weeks of pregnancy

👉🏻 Followed up to 20 weeks

👉🏻 No increased risk of miscarriage following vaccination.

🧵…

researchsquare.com/article/rs-798…
This is a follow-up to this older study in the same cohort. The older version of the study showed no increased risk of miscarriage following vaccination, but the follow-up time was shorter (10-12 weeks). 2/

nejm.org/doi/full/10.10…
Although the data from this study was reassuring, the limited follow-up time made it difficult to exactly calculate the miscarriage rate following vaccination, so an estimate was used.

I’ve discussed that here… 3/
Read 11 tweets
10 Aug
Who's been waiting for UK data on the safety of #COVID19 #vaccines in #pregnancy? 💉🤰🏽🇬🇧🤔

🙋🏻‍♀️

Well now we have some!

(TLDR: No concerns arising from this study)... 🧵

ajog.org/article/S0002-…
This study looked at people coming to give birth at St George's hospital in London between March 1st and July 4th 2021.

141 had had at least one dose of a COVID vaccine

1187 were unvaccinated. 2/
(And for those always on the hunt for data about the AstraZeneca vaccine in pregnancy... 13 of the vaccinated people had had AZ.) 3/
Read 7 tweets
19 Jul
After I wrote this thread about the potential effects of COVID vaccination in pregnancy and the lack of such effects in other vaccines, perinatal epidemilogist @deshaynef got in touch to tell me about some work she has done in this area... 🧵
Her group has published two papers doing 3-5 year follow-up on the babies of people vaccinated against flu in pregnancy.

👉 Flu vaccination in pregnancy was not associated with adverse outcomes in children later on. 2/
Read 5 tweets
19 Jul
"I'm #pregnant and I want to get the #COVID19 #vaccine to protect myself and my baby. But should I wait until after 12 weeks?"

🧵...
Two studies have looked at pregnancy-specific adverse events following COVID-19 vaccination in the first trimester of pregnancy.

Both found no increased risk of miscarriage.... 2/

nejm.org/doi/full/10.10…

jamanetwork.com/journals/jama/…
The other thing that is a theoretical worry in the first trimester is a high fever (more than 39C for more than 24h) affecting the baby's development.

Although mild fevers are a common side-effect of vaccination, a fever as severe as this is really uncommon... 3/
Read 11 tweets
16 Jul
A question I get asked *a lot* is…

“What are the long-term effects on babies born after #COVID19 #vaccination in #pregnancy?”

So let’s talk about what we know… 🧵
Let’s start by looking at the effects at birth. We now have four large datasets from three countries telling us that babies born after vaccination in pregnancy are normal. 2/

USA

nejm.org/doi/full/10.10…

medrxiv.org/content/10.110…
Read 12 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!

:(