Vass Vassiliou Profile picture
Aug 27, 2021 12 tweets 13 min read Read on X
#ESCCongress #ESCGuidelines This is a Long thread on Heart Failure Guidelines published @escardio #EHJ academic.oup.com/eurheartj/adva… LONG BUT EDUCATIONAL! Focus on CHRONIC HF #epeeps #CardioEd @AlexFrogoudaki @mmamas1973 @DrMarthaGulati @purviparwani @Filippatos @EkateriniL @Hragy …/2
#ESCCongress Firstly, no longer Mid Range, replace by MILDLY REDUCED LV EF. Makes a lot of sense - in fact for some time I thought the previous guidelines referred to ‘mildly reduced’ until @merinopoulos corrected me… otherwise no real change in the nomeculture …/3
#ESCCongress nice algorithm - assess risk factors… do BNPs (watch the caveats- AF ⬆️ , obesity ⬇️ value so bear this in mind. The #echofirst and classification into Reduced, mildly Reduced and Preserved. @SineadHughes19 @wordfinga @rahatheart1 @HEARTinMagnet @bp_halliday …/4
#ESCCongress symptoms reaffirmed (ok nothing new here) and doses of medication - please STOP THE PRESCRIPTION OF RAMIPRIL 1.25mg! @ShrillaB @MadalinaGarbi @nabeelsheikh99 @pharmabadboy @Johnett72359965 …/5
#ESCCongress & MY FAVOURITE PART. #WhyCMR mainly focused on utilising w poor echo Windows (agree), rule out infiltrative conditions (agree) + to look for LGE in DCM - well here I agree but I think the recommendation could have been stronger here, the evidence is overwhelming …/6
#ESCCongress and a nice info graphic on what each medication 💊 benefits… ACE I/ARNI & Beta blockers & MRA & SGLT2i FOR HFrEF. Again no real change from the recent additions to the guidelines …/7
#ESCCongress on the basis of LVEF and QRS a decision about ICD vs CRT. Am a bit uncomfortable for the IIa for non-ischaemic cardiomyopathy for ICD. We know arrhythmia in NICDM is driven more by mid wall LGE than EF. EF drives heart failure deaths. Time to have included scar …/8
#ESCCongress moving to MILDLY REDUCED LVEF…remember this is anyone with EF 41% upwards. All tablets only given class IIa- I.e ‘can be considered’. I think this could have been a IIa recommendation. And doesn’t include SGLT2i- Emperor-Preserved suggests benefit in this group …/9
#ESCCongress and the role of rehab following heart failure? A definite YES! Let’s not forget that! Use of TELEMEDICINE- possibly consider. I would say definitely during current times in #covid- as hybrid at least! …/10
#ESCCongress and for advanced heart failure- a nice diagram! But suggest you get your local specialist like @drstephenpettit for specific advice! …/11
So coming to the end- what is the short summary?
1- new name- mildly reduced than mid-range 2- therapy different for each category 3- tablets same as before, SGLT2i in HFrEF 4-remember ICD, CRT- ivabradine if needed …/12
And last tweet 5- HFmrEF drive to treat same way as HFrEF, lower level evidence. I have to say I enjoyed this guideline, shortish (95 pages) to the point and relatively up to date- although it already needs revisions (Emperor-Preserved for HFmrEF group) Thank u 4 reading. THE END

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More from @vass_vassiliou

Nov 28, 2021
A thread 🧵 on #omicron #covid #mask #vaccines Almost 2 years since the initial Covid concerns, what we’ve had is governments across the world being reactive (and slowly) not pro-active. So why is this #omicron different, and what is the concern? @DrMarthaGulati @mmamas1973 /2
Multiple mutations have happened- we didn’t get from #delta to #omicron overnight, the other variant were monitored, but not alarming… and scientists kept observing… but not shouting out- now they are, time to be listened, and here are the concerns @AnastasiaSMihai @iamritu /3
#omicron has 32 mutations in its spike protein. These include E484A, K417N and N440K, which are might the virus to escape detection from antibodies… and herein lies the question… WILL THE VACCINES WORK? WILL NATURAL IMMUNITY WORK? @N_Dietis @LynnGreigMiller /4
Read 14 tweets
Oct 24, 2021
It was so great to give a (virtual) talk to the Hellenic Society of Cardiology on #covid and #whycmr- hopefully next year in person with no more need 4 Covid talks! Short 🧵 on CMR use #epeeps #cardioed #echofirst #tavr #metaanalysis …/2
#covid is bad for many organs- including the heart. The role of ACE2 receptors to facilitate entry to the cells is well known! But for the heart Covid does lead to #infarction #arrhythmias #heartfailure #myopericarditis What can you do to avoid this? GET A #VACCINE
Hospitalized patients with high troponin are the sickest ones. Great study from #london hospitals showing that in this cohort - late gadolinium enhancement indicating scar (an adverse prognostic factor) is present in 1/2 patients. How to avoid it? GET A #VACCINE …4
Read 9 tweets
Aug 30, 2021
#ESCCongress THREAD on CVD PREVENTION. I need to start with this, seeing someone with an MI or heart failure or AF & treating them appropriately doesn’t make us great doctors. PREVENTING those does. These #ESCGuidelines help a lot to getting us there @ShrillaB @wordfinga …/3
#ESCCongress #ESCGuidelines on CVS PREVENTION. A 🧵. Who to assess? ANYONE AT RISK! Those with FHx, DM, HTN, high lipids AND OBESITY… don’t forget Obesity! I would also have included sedentary lifestyle! @bes502 @papathanasiou_ @MichaelPapadak2 @PMarquesVidal @DrTiberi …/4
Read 14 tweets
Aug 28, 2021
Educational Thread (longish) on AORTIC STENOSIS on the new #ESCGuidelines #ESCCongress published at @escardio #EHJ academic.oup.com/eurheartj/adva… Another thread to follow on AR. So truly excited about these guidelines and here’s why @mirvatalasnag @mmamas1973 @DrMarthaGulati @Hragy …/2
First things first #ESCCongress - a patient centered approach recommended. 👏 but I thought we had long moved to a patient centred approach but nonetheless good to highlight #epeeps #cardio #echofirst #whycmr …/3
#ESCCongress valve guidelines - and the role of the Heart Team re- emphasized. This is crucial. But also defining who should be present to constitute a ‘Heart Team’ @milena_mate @MelissaLyleMD @drzgezdentok1 @AScatteia @RositaZakeri @pacman8it @dr_benoy_n_shah @tchaaban1 …/4
Read 11 tweets
Sep 1, 2020
#ESCCongress has ended. A unique conference! An unforgettable conference! These are my highlights!

Firstly, an amazing DIGITAL experience... Brining everyone together, breaking all barriers, diminishing borders.

@Barbara_Casadei @Steph_Achenbach @mmamas1973 @DrMarthaGulati
In an earlier (still ongoing) Poll from today... 77% wished to have a hybrid Digital and In Person conference... That would certainly have lots of attractions especially for those who wouldn't other be able to afford it #ESCCongress



@MarziaRigolli
...& now the science! In random order (depending on which I could find in my twitter thread most easily!)

No 1. #Covid and the HEART

HTN, Lipids, Diabetes, CAD, heart failure, ALL associated with worse prognosis (critical events & deaths)

Women have it less severely

#EPeeps
Read 16 tweets
Aug 30, 2020
An EXCITING NEW guideline from @escardio at #ESCCongress on Atrial Fibrillation. It’s a long read of 126 but enjoyable! Here are my top tips from this guideline…#epeeps Link: bit.ly/2YRdX8S @mmamas1973 @pash22 @Hragy @DrMarthaGulati @ErinMichos @AnastasiaSMihai /THEAD
FOCUS is on CONFIRMING AF (12 lead >30s) and CHARACTERISING it…
The 4S….

Stroke Risk…
Symptom Severity…
Severity Burden of AF
Substrate of AF

@KTamirisaMD @StavrosStavrak1 @StavrosDrakos @JonathanBehar @bogdienache @mencardio
#ESCCongress /3
AF ESC GUIDELINE Tweetorial

Stroke Risk – Simple – CHA2DS2-VASc Score
& HAS-BLED, to stratify bleeding
Symptom severity- Use the EHRA symptom scale
Burden- paroxysmal, persistent, permanent and if paroxysmal how frequently
Substrate of AF- comorbidities #ESCCongress /4
Read 15 tweets

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