Ivermectin 0.2-0.4mg/kg works at the outer and inner part of cells, thru P2X, GlycineCls, has anti-inflammatory effects, proven for decades, etc.
Molnupiravir 800mg twice a day for 5 days, works thru the RdRp. Can this antiviral have the side effects similar to Remdesivir ?
Molnupiravir 800mg twice a day for 5 days, works thru the RdRp. Can this antiviral have the side effects similar to Remdesivir ?
https://twitter.com/DrEricDing/status/1443880627837734946
Comparison studies about Molnupiravir.
Gordon et al. : the high frequencies of G-to-A and C-to-U transition mutations in coronaviruses exposed to molnupiravir.
#host DNA #mutagenesis possibility
nature.com/articles/s4159…
Gordon et al. : the high frequencies of G-to-A and C-to-U transition mutations in coronaviruses exposed to molnupiravir.
#host DNA #mutagenesis possibility
nature.com/articles/s4159…
Kabinger et al. entertains A-to-G transitions, which can occur in coronaviruses exposed to molnupiravir, albeit at much lower frequencies.
Thus, although the biochemical evidence indicates that molnupiravir triphosphate (MTP)
is a better CTP (natural nucleotide) analog, the ..
Thus, although the biochemical evidence indicates that molnupiravir triphosphate (MTP)
is a better CTP (natural nucleotide) analog, the ..
genetic data suggest that MTP can compete weakly with UTP, inducing A-to-G transitions.
Sheahan et al. did not observe mutagenesis of host (us, human) mRNA.
Sheahan et al. did not observe mutagenesis of host (us, human) mRNA.
It has been suggested that exposure to molnupiravir can be mutagenic to host DNA during host DNA replication.
#host #human #DNA #mutagenesis
#host #human #DNA #mutagenesis
• • •
Missing some Tweet in this thread? You can try to
force a refresh
