NYC is flooded with high-speed bikes, motorized with throttles, violating every traffic rule & imperiling legit cyclists & pedestrians. There are 65,000 of them. Why? Blame Relay relay.delivery/couriers a Uber-like dispatching company that handles almost all the deliveries..
MORE
2/ ...for companies like @DoorDash & @Grubhub . The bikers compete to get better assignments based on their speed records, so of course they ride illegal fake-bike motorcycles, break every traffic law, even do 20 mph on sidewalks. Nobody tells Relay to change the algorithm.
MORE
3/ Across urban USA the streets are more congested & tensions betwn regular bikes, cars, trucks, buses, pedestrians & throttle bikes are rising. This is going to worsen unless it's regulated, because MORE e-bikes, e-skateboard-scooters & mopeds are coming.
nytimes.com/2018/10/09/nyr…

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More from @Laurie_Garrett

7 Oct
The Israeli findings regarding @pfizer #COVID19 2-dose vaccination & heart inflammation found 136 cases out of 5 million vax recips:
"a risk that was more than twice that among unvacc'ed persons. This was highest in young male recipients..."
MORE
nejm.org/doi/full/10.10…
2/ More from Israel
"In our study, definite or probable cases of #myocarditis among persons between the ages of 16 & 19 years within 21 days after the 2nd vaccine dose occurred in 1 of 6637 male recipients & in 1 of 99,853 female recipients."
MORE
3/ A 2nd Israeli study of @pfizer vax recips found, "the est'ed incidence of #myocarditis was 2.13 cases per 100,000 persons; highest among male patients between the ages of 16 & 29 years. Most cases of myocarditis were mild or moderate in severity."
nejm.org/doi/full/10.10…
MORE
Read 8 tweets
3 Oct
Two important #COVID19 treatment studies were released this week. One, from @Merck got a lot of attn and soared on the stock markets. The other, with better results, from @Regeneron got little notice.
Key point with both: Best results come from treatment before symptoms.
3 MORE
2/ @Merck press release: Gave molnupiravir to 385 people w/#COVID19 & placebo to 377.
After 29 days, 7.3% of molnupiravir group were either hospitalized or died, vs 14.1% of placebo-treated. So, says Merck, the drug cut the risk of severe COVID by 50%.
s2.q4cdn.com/584635680/file…
3/ @Regeneron made combo monoclonal antibody treatment, REGEN-COV & pub'ed data in @NEJM .
28 days post-treatment, 1.3% of 1,355 treated patients were hospitalized or died, vs 4.6% of 728 placebo recipients.
So, REGEN-COVID cut acute disease risk by 71%.
cidrap.umn.edu/news-perspecti…
Read 4 tweets
22 Sep
What @JoeBiden promised at #COVID19 summit today
1. "donating 1.1 billion doses of COVID-19 #vaccines to the world, free of charge, no strings attached."
2. "for every one shot we have administered in this country to date, we are now donating three shots to other countries."
MORE
2/
3. "solving the global oxygen crisis, making tests and therapeutics more available, and enhancing access to personal protective equipment."
4. "preparing for the next pandemic by establishing a sustainable health security financing mechanism"
MORE
3/
5. "The summit is meant to be a deliberate beginning to the end of the pandemic, and it will launch a lot of work."
6. "we plan to take a leading role in tracking collective progress"
7. "support a COVID-19 TRIPS waiver"
8. "We will share through COVAX," not bilaterally.
MORE
Read 5 tweets
17 Sep
Big news from Laos @PasteurVirology relevant to the origins of #SARSCoV2:
"our results pinpoint the presence of new bat sarbecoviruses that seem to have the same
potential for infecting humans as early strains of SARS-CoV-2."
MORE

researchsquare.com/article/rs-871…
2/
"People working in caves, such as guano
collectors, or certain ascetic religious communities who spend time in or very close to caves, as well as
tourists who visit the caves, are particularly at risk of being exposed. Further investigations are needed to
assess..."
MORE
3/
"...if such exposed populations have been infected by one of these viruses, if these infections are
assoc'ed w/symptoms, & whether they could confer protection against subsequent #SARSCoV2
infections."
AND, they found, "sequences very close to
those of the early..."
MORE
Read 8 tweets
17 Sep
In today's hearing @US_FDA on @pfizer request for approval of 3rd #COVID19 #booster #vaccine the company presented data on its original 2020 study volunteers, many of whom originally got placebos. All those people were eventually given 2 doses of vax, but months after the..
MORE
2/...matched study pool that was vaxed from the start. This created a staggered time set for looking at duration of immunity, and then comparing impact of giving all of them a 3rd dose. They looked at protection against original (WT) form of #SARSCoV2 & beta (SoAfrica) type.
MORE
3/ The @pfizer conclusion is that #vaccine efficacy definitely wanes over time, a 3rd dose works to boost it, said dose is safe and powerful. Company said 1.8 million more cases of severe #COVID19 wld occur in USA this year w/out 3rd dosing.
MORE
Read 5 tweets
17 Sep
Hearings today @US_FDA on @pfizer application to give 3rd doses of #COID19 #vaccines . Much rests on the Israeli findings. Two reps of their MOH presented details, which are significant because Israel's mass vax is abt 3 months ahead of Europe & UK & USA.
MORE
2/ Israel 1st rolled out mass vax in December, and the impact against routine forms of #COVID19 was excellent. It seemed that a standard @pfizer #vaccine protocol worked beautifully.
BUT, MORE
3/ But then, Israelis told @US_FDA , the #DeltaVariant slammed Israel and #COVID19 incidence in all age groups, including among fully vaccinated, soared. The question was why.
MORE
Read 12 tweets

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