You may have heard about the viral abstract from the @AHAScience saying cardiac risks increase after Covid vax. Note- not everything the AHA produces is a well reviewed clinical practice guideline or meta-analysis. Lets think this through.
If you do a test looking for inflammation after a procedure designed to produce an immune response… you will find… inflammation. The results in the abstract do not mean what you think they do.
The author is a cardiac surgeon turned holistic health practitioner. He had a cohort of patients who had PULS blood tests pre vaccination done at baseline (probably in his clinic based upon the abstract). He got some patients vaccinated, and then he repeated the PULS afterwards.
The test itself is designed to predict who might have a vulnerable plaque, which is a major cause of heart attacks. The search for which plaques are vulnerable and which are more solid ***is a legitimate clinical mystery***. Its extension to vaccination is not legitimate.
The actual panel includes the things below, and a risk score is calculated.
There are several lessons here-
1. Laboratory tests, especially those taken outside the original testing parameters, do not directly equal clinical outcomes.
2. An abstract is the most basic level of science submission that can be sent to the AHA. There is very limited peer review.
3. Routinely ordering the PULS can be done in a Cardiology clinic but for now is not standard of care. We have formal clinical guidelines on how to reduce heart attack risk.
4. We do know the clinical issues that happen after Covid vaccines now, very very well. This type of study is superseded by large clinical studies such as those done by the CDC Vaccine Safety Datalink or Israeli MOH.
5. There was no effort to compare results with other adult vaccines such as pneumonia boosters or adult flu vaccines.
6. There was no effort at all to make a control group.
7. If you run a test designed to seek out inflammation after delivering a medicine designed to elicit inflammation, you will find inflammation. A test used outside of its normal parameters should be used with caution.
8. Keep on being inspired to learn how science research works. Read the actual articles themselves to figure them out.
With credits to a couple of other cardiologists for showing this - its important to look at his actual presentation slides. Here, he has no disclosures, but he still wants you to buy his products (which is a standard Conflict of Interest in any reputable journal):
He reports data exists on 566 patients but displays only 2 (such studies usually attempt to analyze the data in aggregate):
And in the conclusions he recommends quercetin and aspirin, which he does not have the data analysis to support (you would want to at least show your PULS numbers decrease with aspirin / quercetin). For all these reasons, interpret this abstract with caution.
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Here's how @RobertKennedyJr got it all wrong with the #vaccines on his @joerogan podcast. A thread dealing with his entire interview would be endless, so this is sticking to his statements on vaccines.
1. "why is it that CDC and every state regulator recommends that pregnant women do not eat tuna fish to avoid the mercury, but that CDC is recommending mercury-containing flu shots with huge bolus doses of mercury, I mean, massive doses, that pregnant women in every trimester..."
This sentence is simultaneously, wrong, misleading, and pulling on the emotional heartstrings. As a chemistry graduate I can see through his first lie, which is to conflate all types of mercury with each other. Ethyl mercury 🚫methyl mercury🚫mercury metal.
MSAmitripped did a superlative job in the face of all the usual #debate tactics. The discussion centered around the usual talking points, but here's where the discussed went off the rails:
1. People who were in Kirsch's camp felt the need to mansplain and talk over MSAmitripped to show their points. PSA: Normal gentlemanly manners, and proper science communication, dictates that you shouldn't need to mansplain and shout to make your point.
Congrats to the team out of #southkorea for completing a huge #COVID19 💉 #myocarditis study on their entire population to better characterize immunization myocarditis for all of us. Let's talk about what the paper really showed, instead of what the pundits think it showed.
I know how much work it is to coordinate all the moving parts and all the healthcare professionals to put together something like this, so if you ever meet this team, they deserve a digital round of applause.
The primary objective was to look at the medium term and long term outcomes of COVID vaccine myocarditis, count the amount, stratify by age, and find out what the most severe outcomes were. There were several levels of results, some of which confirm other studies, others are new:
@drcole12 is making mistakes here that even a #pathology trainee would be embarrassed to make. His core claim is that spike protein from vaccines is inducing blood clotting. This is generally false.
The source of his data is @ArneBurkhardt , who first off, makes so many logical errors that it deserves a thread of its own.
Next, Cole presents slides from Burkhardt's presentation free of context, to give the reader a veneer of legitimacy, but in reality, all deceased people have blood clots. The basis of his claim is essentially the slide shown above, with an absence of awareness of basic dying.
#Enterovirus#Myocarditis is getting a lot of attention in the media right now so, I'm here to share a general overview of what this is.
According to our professional organization, @ACCinTouch , the definition of myocarditis is any condition that causes inflammation of the heart. There are a big list of causes, and the most common ones in adults are different from the most common ones in kids.
Enterovirus is a specific category of virus, and it is one of the infections (overall most common cause in all ages) which is capable of causing heart inflammation.
The most basic way - he blocked almost all of #Medtwitter for disagreeing with him, and simultaneously claims that everyone needs to at least listen to people who disagree.
Whatever happened to actions speak louder than words @VPrasadMDMPH?