[Thread] What is the significance of the license agreement #JnJ will grant @aspenpharma to fill and finish an Aspen brand of #JnJ's #COVID jab?

Aspen will be able to sell their jabs to African countries. Currently they can't, they have to hand the jabs back to JnJ to sell.
2. #JnJ is essentially giving Aspen a voluntary license to make (fill and finish) its vaccine and sharing the intellectual property rights with Aspen to do this.
3. Africa imports 99% of its vaccines from outside the continent. Having an African manufacturer (to fill and finish) that will only supply #COVID19 jabs to Africa will increase access to supplies on the continent.
4. Previously, JnJ sold some of the jabs filled and finished by Aspen in SA, to European countries while SA and other African countries were in desperate need of them. So jabs made on a continent with little supply went to countries with lots of supply. That will now change.
5. Aspen hopes that its license agreement with #JnJ will serve as a blueprint on how to enable local production of vaccines in Africa. It plans to produce 400 million doses of #JnJ's jab per year under the brand name Aspenovax.
6. Stephen Saad, Aspen: More booster #COVID19 vaccine doses have been administered globally than first doses in Africa.
7. #JnJ has also done tech transfer (sharing their know-how) with Aspen when they started to fill and finish JnJ's jabs under their current agreement. What is tech transfer and what happens when drug companies refuse to do it? More here. bit.ly/3D7dRv8

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More from @miamalan

1 Dec
[Thread] 1. From TODAY (1 Dec) adults in SA with certain conditions that weaken their immune systems can access an additional #COVID19 vaccine dose. How do you get a dose? Your doctor/nurse needs to fill out a form. Download it here:
bit.ly/31jRuW4
2. You need to register on the #EVDS for an additional dose and take the form that your doc/nurse filled out with you to the vaccination site. Here's how it works:
3. Which conditions qualify?
1. Haematological or immune malignancy
2. Moderate to severe primary immunodeficiency disorder
3. HIV infection with CD4 count < 200 cells/µL within the last 6 months
4. Asplenia

Source: bit.ly/31jRuW4
Read 11 tweets
30 Nov
BREAKING [Thread]
1. Janssen Pharmaceuticals will grant @aspenpharma a license 2 fill + finish #JnJ's #COVID19 jab under its own brand + sell it to African countries. Currently, the jabs Aspen "fill and finish" have to be handed back to JnJ + they then sell it to who they want.
2. The jabs that Aspen will "fill and finish" under the new agreement will:
1. Be called Aspenovax (#JnJ will give Aspen the IP rights to make its own brand)
2. Will use drug substance (the key ingredient) supplied by JnJ
3. Aspen will be able to sell its Aspenovax jabs (the same thing as a #JnJ jab, just a different name) to
public sector markets in Africa through transactions with designated multilateral organisations and with national governments of member states of the African Union.
Read 4 tweets
29 Nov
[Thread] 1. How many hospitals in SA report on #COVID19 hospital admissions?

666 (408 = public sector, 258 = private sector, see the provincial breakdown on the table below)

Source: Waasila Jasat, @nicd_sa
2. Here is how admissions have changed in provinces over the last 28 days. See how admissions have increased by 169,02% in Gauteng (where the #Omicron variant outbreaks started).
3. There have been sharp week on week increases in hospital admissions in Tshwane (where #Omicron was 1st detected in Gauteng). No increases in deaths have yet been seen (but deaths always lag a few weeks behind admissions).
Read 7 tweets
29 Nov
[Thread] 1. @ProfAbdoolKarim on the #OmicronVariant globally:

1. Globally #COVID19 case numbers are increasing
2. The WORLD might be entering a 4th #COVID wave
2. Variants have changed the #COVID19 endgame. Each SA #COVID wave = driven by a different variant with different characteristics:

Wave 1: Wuhan variant
Wave 2: Beta variant (more transmissible than Wuhan, immune escape abilities)
Wave 3: Delta (more transmissible than Beta)
3. #COVID19 case surges have been caused by different variants in different countries.
India = #DeltaVariant
Brazil = Gamma variant
SA = #Beta (Wave 2), Delta (Wave 3)
Read 15 tweets
28 Nov
[Thread]
1. #CyrilRamaphosa:
1. SA = deeply disappointed in countries who have implemented travel bans @ SA. We urgently + immediately call on them 2 reverse the bans
2. There is no scientific justification 4 such bans. All they do is damage the economies of southern Africa
2. #CyriRamaphosa:
#COVID19 travel ban decisions don't respect the recent G20 declaration in which there is a commitment to help the tourism sectors of all countries to recover. Travel bans do exactly the opposite + are in contravention of the declaration.
3. #CyrilRamaphosa:
Some countries that have implemented travel bans @ SA:
UK, EU countries, Canada, Turkey, Sri Lanka, UAE Seychelles, Thailand
Read 4 tweets
28 Nov
1/4 NB points made by @yodifiji of the AU's Vaccine Delivery Alliance:

The #OmicronVariant was inevitable because of the world's failure to vaccinate countries equitably.

What contributed?
- Wealthy countries' hoarding
- Manufacturers' refusal to share IP rights/know-how
2. @yodifiji:
Now those same wealthy countries who hoarded vaccines and contributed to inequity want to keep out Africans — #Omicron has been detected in several countries. But there are no travel bans for Belgium or Israel, only for African countries.
3. @yodifiji:
Had the original #SARSCoV2 1st been detected in Africa (and not China), the world would likely have "thrown away the key" + locked us out. Africa would have become known as the continent of #COVID19 + vaccines would not have been developed a urgently as currently.
Read 4 tweets

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