[Thread] 1. From TODAY (1 Dec) adults in SA with certain conditions that weaken their immune systems can access an additional #COVID19 vaccine dose. How do you get a dose? Your doctor/nurse needs to fill out a form. Download it here:
bit.ly/31jRuW4
2. You need to register on the #EVDS for an additional dose and take the form that your doc/nurse filled out with you to the vaccination site. Here's how it works:
3. Which conditions qualify?
1. Haematological or immune malignancy
2. Moderate to severe primary immunodeficiency disorder
3. HIV infection with CD4 count < 200 cells/µL within the last 6 months
4. Asplenia

Source: bit.ly/31jRuW4
4. People on these treatments also qualify for additional #COVID19 vaccine doses:

1. High dose steroids or systemic biologics (e.g. for autoimmune conditions)
2. Long term renal dialysis
3. Transplant recipients (solid organ or bone marrow)

Source: bit.ly/31jRuW4
5. Are additional vaccine doses boosters? No.

They're called additional doses because they're 4 people with immune systems so weak that the normal nr of doses = not sufficient. These doses = part of the primary vaccination schedule 4 such people.

More: bit.ly/3obEmvc
6. Why don't all people with #COVID19 comorbidities get extra doses?

Not all people's immune systems = so weak that the normal nr of doses don't work well enough. Extra doses = not given because the efficacy of jabs wane over time, but because of very weak immune systems.
7. Is the time frame for when to take an additional dose the same as for boosters? No.

E.g.: A #Pfizer booster (3rd shot), is normally taken 6 months after the 2nd shot. An extra Pfizer dose can be taken from 28 days onwards after the 2nd shot.

Source: bit.ly/31jRuW4
8. Can teens (between 12 and 17 years) get additional doses? No. Only adults (people of 18+) in SA qualify at this stage.

Source: bit.ly/31jRuW4
9. Can you mix and match doses for an additional doses in SA? Not at this stage.

- If you had 2 #Pfizer shots, you need to take a 3rd Pfizer shot.
- If you had 1 #JnJ shot, you need to take a 2nd JnJ shot.

Source: bit.ly/31jRuW4
10. When will #COVID19 vaccine boosters become available in SA?
@healthza:
1. Sahpra's decision re #Pfizer's booster application expected soon (no boosters can be rolled out without approval)
2. The vaccine MAC's recommendation to @healthza re boosters = expected this week
11. Who will receive #COVID19 vaccine boosters first in SA?

@healthza says:
Boosters will be phased in, starting with boosters for people of 60 years and older.

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More from @miamalan

3 Dec
[Thread] @nicd_sa, Michelle Groome and Waasila Jassat:

1. SA's 7-day moving average of new daily #COVID19 cases has increased from 332 on 16 Nov to 4,814 on 1 Dec (particularly high increase over the last 2 days)
2. This increase is unprecedented (higher than in any other wave) Image
2. The most rapid increase in new #COVID cases has been seen in Gauteng (red line on left graph) Image
3. Test positivity rates are a good indication of how rapidly a virus is spreading. + rate = nr of tests coming out +.

Over the past week SA's test +rate for #COVID19 has increased from 1-2% to Thurday's 22.4%. Increases over the last 3 days have been particularly high. Image
Read 16 tweets
3 Dec
#JoePhaahla: [Thread]
1. 8 days ago SA announced the detection of the #OmicronVariant
2. SA's daily new #COVID19 cases = increased rapidly (within a wk) from a few 100 2 Thu's 11,535
3. Much steeper rise than in previous waves
4. + rates = increased from 1-2% (wk ago) to 22.4%
2.
1. The #OmicronVariant outbreaks started in Tshwane and then spread to Jhb, Ekurhuleni and Sedibeng
2. It has now spread to every province
3. Increases huge in: WC, KZN, LP, NW, MP (only FS and NC still relatively low nrs)
3.
1. We have 47 000 active #COVID19 cases and hospital admission are below 3000
2. We've seen many vaccinated people getting infected with the #OmicronVariant, but cases seem to be mild
3. We have spare be capacity in both the private and public health sectors
Read 4 tweets
30 Nov
[Thread] What is the significance of the license agreement #JnJ will grant @aspenpharma to fill and finish an Aspen brand of #JnJ's #COVID jab?

Aspen will be able to sell their jabs to African countries. Currently they can't, they have to hand the jabs back to JnJ to sell.
2. #JnJ is essentially giving Aspen a voluntary license to make (fill and finish) its vaccine and sharing the intellectual property rights with Aspen to do this.
3. Africa imports 99% of its vaccines from outside the continent. Having an African manufacturer (to fill and finish) that will only supply #COVID19 jabs to Africa will increase access to supplies on the continent.
Read 7 tweets
30 Nov
BREAKING [Thread]
1. Janssen Pharmaceuticals will grant @aspenpharma a license 2 fill + finish #JnJ's #COVID19 jab under its own brand + sell it to African countries. Currently, the jabs Aspen "fill and finish" have to be handed back to JnJ + they then sell it to who they want.
2. The jabs that Aspen will "fill and finish" under the new agreement will:
1. Be called Aspenovax (#JnJ will give Aspen the IP rights to make its own brand)
2. Will use drug substance (the key ingredient) supplied by JnJ
3. Aspen will be able to sell its Aspenovax jabs (the same thing as a #JnJ jab, just a different name) to
public sector markets in Africa through transactions with designated multilateral organisations and with national governments of member states of the African Union.
Read 4 tweets
29 Nov
[Thread] 1. How many hospitals in SA report on #COVID19 hospital admissions?

666 (408 = public sector, 258 = private sector, see the provincial breakdown on the table below)

Source: Waasila Jasat, @nicd_sa
2. Here is how admissions have changed in provinces over the last 28 days. See how admissions have increased by 169,02% in Gauteng (where the #Omicron variant outbreaks started).
3. There have been sharp week on week increases in hospital admissions in Tshwane (where #Omicron was 1st detected in Gauteng). No increases in deaths have yet been seen (but deaths always lag a few weeks behind admissions).
Read 7 tweets
29 Nov
[Thread] 1. @ProfAbdoolKarim on the #OmicronVariant globally:

1. Globally #COVID19 case numbers are increasing
2. The WORLD might be entering a 4th #COVID wave
2. Variants have changed the #COVID19 endgame. Each SA #COVID wave = driven by a different variant with different characteristics:

Wave 1: Wuhan variant
Wave 2: Beta variant (more transmissible than Wuhan, immune escape abilities)
Wave 3: Delta (more transmissible than Beta)
3. #COVID19 case surges have been caused by different variants in different countries.
India = #DeltaVariant
Brazil = Gamma variant
SA = #Beta (Wave 2), Delta (Wave 3)
Read 15 tweets

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