1/ This week’s #ThrowbackThursday tweetorial is a quick reference to the Banff classification which traces its origin to one of the most beautiful places in North America.
2/ In 1991, the first conference was conducted in Banff Canada and included a multidisciplinary team. At this time there were considerable differences between pathologists for biopsy interpretation. A standardized approach to improve patient care was proposed.
4/ Over time, the criteria has been updated as biannual meetings were held and the most recent comprehensive criteria, from the 2017 meeting, is shown below. pubmed.ncbi.nlm.nih.gov/29243394/
6/ And finally, the 2019 meeting provided updates on chronic active T-cell mediated rejection as well as borderline rejection and antibody-mediated rejection. onlinelibrary.wiley.com/doi/full/10.11…
7/ These criteria for evaluation allograft rejection have been enormously useful to the field of nephrology. More information on The Banff Foundation for Allograft Pathology can be found here. banfffoundation.org
2/ Bleeding can occur at 3 sites:
🚩Into the collecting system➡️ microscopic or gross hematuria ➡️ureteral obstruction
🚩Underneath the renal capsule ➡️ pressure tamponade & pain
🚩Into the perinephric space ➡️ hematoma formation pubmed.ncbi.nlm.nih.gov/10846435/
3/ Rarely, severe bleeding may occur due to puncture of : 🩸
📌renal artery,
📌aorta
📌venous collaterals ( in renal vein thrombosis)
2/ In late September 1918, Dr. Ernest Goodpasture admitted a patient to the hospital with what initially appeared to be a quote “typical attack of influenza.” He presented with a 3 day history of cough, dyspnea and fever to 103.0.
3/ He had no clinical evidence of pneumonia. His fever resolved and he was discharged home 3 days later. He felt ill after discharge, but returned to work. His cough persisted though, and weight loss and fatigue worsened.
3/ 3% of the general population >50 years old has MGUS and only a small percentage (1%) progress to malignancy such as myeloma or lymphoplasmacytic lymphoma. These patients are observed over time and no chemotherapy is given