BREAKING🔔 The 7th preprint from G2P-Japan🇯🇵 is out @biorxivpreprint. #Omicron BA.2 variant seems to be more contagious and pathogenic than BA.1 variant. Please RT. 1/5
biorxiv.org/content/10.110…
biorxiv.org/content/10.110…
1⃣ Statistical analysis shows that the effective reproduction number of BA.2 is 1.4-fold higher than that of BA.1. 2/5 
2⃣ Neutralization experiments show that the vaccine-induced humoral immunity fails to function against BA.2 like BA.1, and notably, the antigenicity of BA.2 is different from BA.1. 3/5
3⃣ Infection experiments using hamsters show that BA.2 (note: because clinical isolates of BA.2 have not been obtained yet, we generated a chimeric virus bearing BA.2 S by reverse genetics) is more pathogenic than BA.1. 4/5
▶️ Our multiscale investigations suggest that the risk of BA.2 (a.k.a. "stealth Omicron") for global health is potentially higher than that of BA.1. 5/5
⏩ Viral genome sequences of BA.1 and BA.2 is ~2-fold more different from those of an original Wuhan-Hu-1 and #Delta and #Alpha. We showed the virological features of BA.2 is clearly different from that of BA.1. Should BA.2 be given a letter of the Greek alphabet? 5/5+1
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