Long Thread on Health Risks with Reinfection . While the Herd Immunity brigade has been pushing their agenda,we need to understand the risk of multiple reinfections .It is an interesting cohort with 12.29% with 2 reinfections 0.76% with 3,.08 with 4 ctd).doi.org/10.21203/rs.3.…
Ctd2)Clearly the time for reinfections is getting shorter 79 for 2nd to 65 days for 3rd & so on.Also the hazard is not only to the lungs BUT also to heart,blood vessels ,Gastrointestinal systems, kidney , the brain, the soft tissues and bones & the brain in that order ctd)
Ctd3) clearly if you are not vaccinated you are at higher risk BUT only vaccination isnt enough #VaccinePlus strategy is important , the risk remains high for 6 months with measurable reduction every 30 days BUT we are getting reinfected in that period (now 65 days ) ctd)
Ctd4)Compared to 3 infections those infected twice had 30% lesser risk ,& 1 infection had 60% + lesser risk of sequelae including mortality , hospitalizations & #LongCovid.So makes sense to prevent sequential issues.Science will catch up eventually with better tools ctd)
Ctd 5) This brings me to final question- What do we do ?? - 1) Mask with #N95 as a principle in public places 2) Get boosted 3) advocate updated vaccines 4) Advocate early treatment & take it 5) advocate for clean air 6) get kids vaccinated 7) help people understand the risk 🙏
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Short🧵How #Covid is killing Health Care Workers ?? Today I met Mrs Tandon.Her husband a 52/M physician had #Covid during #Delta wave which had injured his lungs BUT he came back home & started his private practice.He remained fine till 10 days ago when he made a short trip ctd)
2/n He felt weak on returning & wanted rest .Next day he was feeling body ache , joint pain & slight fever.He tested & found his platelets ⬇️to 23,000 .Further testing showed Dengue-ve.He started feeling dyspnea & was shifted to hospital where his oxygen suddenly plunged.ctd)
3/n Testing Covid+ve,he was already in ICU when the results came & must have infected many.CT very bad.Was shifted on ventilation support but couldn't survive next 24 hrs.3rd case I have heard in last 48 hrs of ⬇️platelets,bodyache & sudden decompensation mimicking Dengue.ctd)
🧵 on why the past experiences aren't good enough #monkeypox disease was first confirmed in humans in 1970.When the outbreak happened most thought it will be a few cases based on earlier outbreaks BUT some of us believed otherwise. See the old tweet ctd)
2/n We were plain lucky to have the West African clade of #monkeypox spread and not the #Congo clade spread , had that happened those who are lecturing is would have been scurrying for cover. Whether it is #Nigeria or it is Globally #monkeypox has broken a lot of barriers.ctd)
3/n with massive undercounting globally we are at 70,000+ cases in 102 new countries.All with availability of #Vaccine & #Tecovirimat in many countries. It would have been thousands more - so even if anyone has experienced the past- it doesn't help - the field has changed ctd)
Short🧵 on the story of the swollen toe - A known of mine phoned 2 days ago, their 19 yr old daughter had suddenly developed a swelling in toe - 2 hrs earlier along with sore throat & slight fever. On my urging they did a rapid test-ve, the RT-PCR ordered for next day -ve ctd)
2/n The fever subsided with naproxen but thereafter neded paracetamol to keep it under check. The mother did not want further testing currently BUT the kid would be in isolation because they have a 90 yr old grandmother living with them .They will watch carefully &masked ctd)
3/n while I was reassuring the mother that it is okay to watch carefully and even though it is most probably #Covid toe , we just need to be very careful she said something and I quote " Dr I am fed up ,this girl is getting fever every 5 weeks ,nothing seems to help" ctd)
Short 🧵 On Persistence of #Ebola - Patient infective over 500 days & spreads infection by Sex- So with the risk of spill over we may see repeated outbreaks. In 2016, Guinea had recorded 3 probable, 7 confirmed cases, of which 6 were admitted at an Ebola treatment unit ctd)
2/n 4 patients died in the community ,4 patients in the ETU.Fatality ratio among probable & confirmed cases in this cluster in Guinea was 80% (8/10).They were closely related to viruses from the 2014–2016 outbreak, ruling out a new introduction from an animal reservoir ctd)
3/n Epi investigation revealed that case 1 had sexual intercourse with a male #Ebola survivor who reported sexual abstinence after discharge from Nov 2014 -August 2015 as recommended. From Sep 2015, he had occasional intercourse with various partners, including case 1 ctd)
Short 🧵 on why some people are showing resistance to acceptance of risk of #Covid. This is a thread not on those who have fallen to misinformation BUT on those who initially took good care, till the vaccines came through - Suddenly become extremely careless & don't mask ctd)
2/n When the pandemic started a physician with army background told me - You know when do maximum casualties take place usually and went to explain & I quote" the maximum casualties dont happen during the 1st 2-3 days when the armies face each other - both sides dig into - ctd
3/n their own bunkers or hide from shelling - The moment they find they are being targeted they jump from one place to another or scurry for cover.After 10 days weariness comes in & with it comes false sense of security or overconfidence in your gear - Ctd)
Short🧵Why I think #Covid can cause existential consequences for Human Race ?? For any species to continue it has to procreate,that depends on fertility of both men & women.We started getting edgy couple of months ago.Here's the original ctd
Ctd3) We know that the number of ova in a woman is fixed at birth.The body doesn't produce more ova.Only a fixed number mature rest die off , maturation needs hormones & lots of other factors. If either hormones or reservoir is reduced #risk ctd) my.clevelandclinic.org/health/article….