I am sure many of you know who @davidludwigmd is, but just in case you are brand spanking new to the low-carb space, I want you to know who he is and that he was at the Metabolic Psychiatry Retreat put on by @janellison and @Metabolic_Mind this year! 🧵(1/8) #metabolicpsychiatry
@davidludwigmd@janellison@Metabolic_Mind@BostonChildrens@harvardmed@HarvardChanSPH He has authored more than 200 scientific articles and presently serves as an editor at The American Journal of Clinical Nutrition and is the author of the #1 New York Times bestseller Always Hungry? Conquer Cravings, Retrain Your Fat Cells, and Lose Weight Permanently. (5/8)
The blood-brain barrier (BBB) is a crucial defense mechanism for the brain, regulating the exchange of molecules between the bloodstream and the brain. When the BBB is disrupted, it can have severe consequences for brain health. (1/12)
Alzheimer's disease is one example of a condition that is exacerbated by BBB disruption. When the BBB is compromised, amyloid beta-peptide deposits can accumulate, leading to #inflammation and disruption of neuronal function. (2/12)
A disrupted BBB in #Alzheimers means astrocyte and microglia inflammation, disruption of synaptic transmission, and myelin destruction. (3/12)
@MujicaParodi@janellison@Metabolic_Mind She made quite an impression on me! My honest-to-goodness thoughts were, "this woman is wicked smart," and "I am so glad she is on our side getting this data!" 😆 (2/11)
@MujicaParodi@janellison@Metabolic_Mind As Director of the Laboratory for Computational Neurodiagnostics (LCNeuro), Lilianne R. Mujica-Parodi leads a multidisciplinary team working at the intersection of human neuroimaging and computational neuroscience. (3/11)
I teach people how to use a ketogenic diet to help with mood and cognitive dysfunction. But that is just the first phase in my online program toward their recovery. (1/10)
Phase 2 consists of teaching people how to do a nutrigenomics analysis for truly personalized supplementation. What is nutrigenomics and why do I think this step is important? (2/10)
Nutrigenomics explores how your genes interact with different foods and nutrients. It can inform you if you may benefit from different types, forms of supplements that improve mitochondrial function. (3/10)
Why do we need seniors to have access to a ketogenic diet to help ward off dementia? Because telling them to eat more fish and blueberries is woefully insufficient! Think I am making this up? I am not. It's time for a thread on a recent study. 🧵 (1/19)
The objective of this study was to examine the relationship between consumption frequency of meat, fish, fruits, and vegetables and long-term risk of dementia and Alzheimer’s disease while taking into account the possibility of protopathic bias (i.e., reverse causation). (2/19)
The researchers analyzed data from the Three-city study, which followed 5,934 volunteers aged 65 and over for 12 years. (3/19)
You may not know who Dr. Carlo Longhiano is, but you will after this thread. I met him at the Metabolic Psychiatry Retreat put on by @janellison and @metabolic_mind this year! 🧵(1/8) #metabolicpsychiatry
@janellison@Metabolic_Mind Dr. Carlo Longhitano is the Associate Professor of Psychiatry at James Cook University (Australia) and a psychiatrist at North Queensland Forensic MH Services. (2/8)
@janellison@Metabolic_Mind He obtained his MD in 1999 (Italy) before completing his psychiatric residency in Oxford and London (United Kingdom). (3/8)
We need to talk about the role of GABA in mental illness and neurological disorders. And then I am going to explain to you why ketones can help regulate this neurotransmitter. 🧵 (1/21)
GABA (gamma-aminobutyric acid) is the main inhibitory neurotransmitter in the brain, and it plays a critical role in regulating neuronal excitability and maintaining the balance between neuronal excitation and inhibition. (2/21)
GABAergic dysfunction has been implicated in a wide range of psychiatric and neurological disorders, including #anxiety disorders, #depression, #epilepsy, #schizophrenia, and #autism spectrum disorders. (3/21)