Thread by @psybalazs

💊Psychonauts of the Multiverse, help me!🍄

I am trying to figure out the best approximate dose conversion between #magicmushrooms and #LSD for a study. Based on #science, 100µg LSD ~ 3.2g dried mushroom (see calc 👇). Is this reasonable based on your personal experiences?

The number I cite above is based on two papers. The first one tinyurl.com/muarwac6 says: "we estimate that 4 g of typically available dried mushrooms (P. cubensis) delivers the approximate psychoactive equivalent to 25 mg of psilocybin"

The other is tinyurl.com/mhrv4kpr: "these results suggest that 20 mg psilocybin is equivalent to 100 μg LSD, and 30 mg psilocybin is equivalent to 150 μg LSD, a consistency that was also noted elsewhere [46]. Thus, the dose equivalence of LSD to psilocybin is ~1:200."

Therefore,
1⃣ 1g dried mushroom ~ 6.25mg psilocybin
2⃣ 1mg psilocybin ~ 0.005mg LSD = 5µg LSD
, which combines to
➡️100µg LSD ~ 20mg psilocybin ~ 3.2g dried mushroom

ps.: if there are any other approaches to the dose conversion in the literature, I would love to know about them as well

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retweets are appreciated🙏