Discover and read the best of Twitter Threads about #placebo

Most recents (7)

#CuratedTruth

"#Homoeopathy is a branch of universal #medicine based on the ‘principle of the like’ (Similia Similibus Curentur = Like treats Like) and in #minimum doses." .. I
It means that a #substance in a massive dose generates #pathological #symptomatology; has the possibility to #cure it, if applied in the #minimum doses obtained by #dilution and intense #agitation, in other words, #homoeopathic #succussion. .. II
#Homoeopathy is derived from a #Hippocratic #concept developed by the #German #physician, Samuel Hahnemann (1755–1843), with serially #diluted #medicines (1:9, 1:99, 1:999 and others) in water-ethanol vehicle alternating #dilution with #succussion. .. III
Read 28 tweets
🔥Thread hydroxychloroquine #HCQ #COVID19

Pourquoi la très grande majorité des médecins s’accordent aujourd’hui pour dire que l'#HCQ ne marche pas ?

Parce que de très nombreuses études montrent son inefficacité et qu'aucune étude de qualité ne montre son efficacité.
👇1/n
Tout en haut de la pyramide de valeur des études, il y a les essais randomisés de grande ampleur. Il y en a désormais 3 sur l’#HCQ dans #COVID19 dont 1 publié (@NEJM) et 2 partagés via communiqué presse (@MartinLandray @ScienceMagazine). On y ajoute 2 méta-analyses solides.

2/n
1er essai : @boulware_dr et collègues

#HCQ en prophylaxie (en prévention de l'infection après exposition à risque) chez 821 patients : autant de patients contaminés par COVID-19 avec #HCQ que #placebo. Effets indésirables plus importants avec #HCQ (40% #HCQ vs 17% #Placebo)

3/n
Read 25 tweets
Updated the #RECOVERYtrial topline results summary table of the #dexamethasone arm compared to usual care for treatment of hospitalized patients with #COVID19.

Got additional information colleagues shared in Twitter.

Thread with some comparisons with #ACTT1

#IDtwitter 1/
the #ACTT1 authors have only reported (preliminary) Day 14 mortality, and the #RECOVERYtrial has only posted Day 28 mortality.

But these days the Supplementary Appendices in trial reports have additional relevant information:
nejm.org/doi/full/10.10…

#DontCoverDiscover
The paper says they were not reporting day 29 mortality, but If you look at Figure S3 in the #NEJM #ACTT1 preliminary report, you have KM estimates out to day 30.

From there you can visualize the probability of death at day

28 (see figure) have left lines and scales
Read 12 tweets
Placebo Effect, one is told a treatment/medicine gives a certain effect. They take an
empty pill & still get the effect.
The mind manifests the effects.
Apply inverse:
“anti-placebo”/“placebo bizarro”
U are told u will get sick if u go outside. The mind manifests the effects!
In 1807, Thomas Jefferson wrote: “One of the most successful physicians I have ever known has assured me that he used more bread pills, drops of colored water, powders of hickory ashes than of all other medicines put together.”
#PlaceboEffect
3. Actually, my meme is inaccurate since Jefferson’s quote finishes calling the physician and his practices “certainly a pious fraud”. Perhaps Jefferson himself missing the simple yet profound point I made with humor above.
Read 15 tweets
#Placebo ja #nocebo - tapauskertomus:
Joukkue jossa junnuna pelasin lätkää, oli pelimatkallaan yöpynyt hotellissa. Ruokailu tapahtui buffetissa yms. josta oli saanut olutta. Nöösit olivat juoneet sitä antaumuksella. Jokainen oli kännissä kuin käki, siihen saakka kunnes selvisi
että kyseinen olut olikin ollut ykköstä. Tämä johti jokaisen spontaaniin selviämiseen.

Tämä vastaava placebo- ja nocebo -efekti näkyy myöskin ilmiössä nimeltä #koronakriisi. Siksikin #priorisointi ja #testaaminen ovat nyt ne ainoat ratkaisut.
Read 3 tweets
Schön, dass Sie nochmal betonen, daran zu glauben, es gäbe Fakten mit unterschiedlichen Besitzverhältnissen.

Meine, deine, unsere, eure, ihre!

Das ist ein Irrglaube! Und leider nicht Ihr einziger ...

#Homöopathie #Fakten
Und schön, dass Sie in Ermangelung besserer Argumente auf irgendwelchen blauen Bändchen herumreiten, die als kleines Dankeschön für die Unterstützung der #Aufklärung in Sachen #Homöopathie verteilt wurden.

Schon gesehen? Ich habe auch eins 🤓

Und nochmal zur Klarstellung:

Weder hasse ich die #Homöopathie, noch möchte ich bezweifeln, dass manch homöopathisch tätiger Arzt oder Heilpraktiker wertvolle Arbeit leisten kann.

Es geht um etwas völlig anderes:

Es geht um Globuli und deren behauptete spezifische Wirkung!
Read 21 tweets
[#Parution] 1999 > Guide pratique de vulgarisation scientifique bit.ly/30XtLX8 par #SophieMalavoy via Gallimard Montréal #LaMethSci
[#Parution] 2014 > Quand le paranormal manipule la science - Comment retrouver l’esprit critique bit.ly/2HJztEi par #SergeLarivée via ed. #PUG #LaMethSci
Read 33 tweets

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