Research focus: Immunology, Immunometabolism, Virology, Infectious Diseases, Surveillance, Public Health. #SciComm #MentorFirst 🇺🇳🇪🇺🇦🇹🏳️🌈
Mar 4, 2021 • 7 tweets • 7 min read
New insights into SARS-CoV-2 immune evasion
#SARS-CoV-2 #mutations can lead to antibody #escape. What about T cells? In our study in @SciImmunology we report how mutated epitopes evade T cell responses. immunology.sciencemag.org/content/6/57/e… 1/7
Using deep viral sequencing we identified low-frequency mutations in experimentally validated CD8 T cell epitopes of SARS-CoV-2, some of which were found as fixed mutations in global virus sequences from @GISAID. 2/7