Thread by @RajlabN

#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

71.3% XBB.1.5
3.6% XBB.1.5.15
2.9% XBB.1.9.1
1.7% XBB.1.16
1.6% XBB.1.5.13
1.5% XBB.1.5.1
1.3% XBB.1.5.17
--
0.7% XBB.2.3

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7
Updated 03/30/23

1/n

Sequence count by US State

#California, #Texas and #NewYork have submitted a big share of sequences with specimen collection dates on or after 03/15/2023

XBB.1.5 is still at the top spot; followed by XBB.1.5.15, XBB.1.9.1 & XBB.1.16

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Granular details -#VariantDashboard #USA #15DayTrends

XBB.1.5* (VOI - @WHO) is still ahead of the other lineages!

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.@CDCgov updated variant proportions estimates on 03/24/2023 (updated every Friday)

XBB.1.9.1 (parent of EG.1*) makes an entrance!

Prudent to start separately tracking XBB.1.5.13 (parent of EK.1* and EK.2*), XBB.1.5.15, XBB.1.16 and XBB.2.3



4/n

Predicted Immune Escape and ACE2 binding of top lineages in USA (relative to BA.2)

Bivalent boosters (OG/Omicron.BA.5) will potentially protect the boosted from getting severe disease/hospitalizations. Get updated if you haven't already!

public.tableau.com/app/profile/ra…

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Predicted Immune Escape and ACE2 binding of top lineages in #California (relative to BA.2)

XBB.1.16 in CA has picked up Spike Y453F (observed in Mink adaptations as well as chronic patients)

More on Spike Y453F from @jbloom_lab


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.@LongDesertTrain & @Asinickle1 can add more about this mutation.. they have been tracking SARSCoV2 lineages with S:Y453F diligently



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USA Airport surveillance update #15DayTrends

132 sequences from 6 US States (#California, #NewYork, #Washington, #NewJersey, #Georgia and #Virginia)

*Includes pooled swabs; Many bad QC seqs

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#Hospital #Capacity - (by State/Division)

All hospitalizations not just COVID-19

public.tableau.com/app/profile/ra…

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#COVID19 #Hospitalizations in the #UnitedStates

>60 yr old & immunocompromised
Have a good look at
@CDCgov

info on #Boosters!

#Ventilate Indoor spaces

Sick? --> Wear a good quality #Mask!

Hospital Tracker (by States, by age group): public.tableau.com/app/profile/ra…

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Circulating recombinant lineages - USA #15DayTrends

XBB.1.5* is still the top recombinant in circulation!

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Status of the latest #COVID19 Wave in #California

Top circulating lineages in CA (#15DayTrends)

XBB.1.5 (66.9%)
XBB.1.5.15 (7.5%)
XBB.1.9.1 (4.9%)
BQ.1.1 (1.4%)
XBB.1.5.13 (1.2%)
XBB.1.5.21 (1.2%)
XBB.1.9.2 (1.2%)
...
XBB.1.16 (0.9%)

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Status of the latest #COVID19 Wave in #NewYork

Top circulating lineages in NY (#15DayTrends)

XBB.1.5 (71.7%)
XBB.1.9.1 (3.9%)
XBB.1.5.17 (2.5%)
XBB.1.5.15 (2.1%)
XBB.1.5.4 (2.1%)
XBB.1.5.1 (1.8%)
XBB.1.9.2 (1.8%)
EL.1 (1.1%)
XBB.1.16 (1.1%)

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Status of the latest #COVID19 Wave in #Texas

Top circulating lineages in TX (#15DayTrends)

XBB.1.5 (74.9%)
XBB.1.5.17 (4.1%)
XBB.1.5.15 (3.5%)
XBB.1.16 (2.5%)
XBB.1.5.1 (1.6%)
XBB.1.5.2 (1.6%)
XBB.1.5.21 (1.0%)
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