Thread by @RajlabN

#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

71.1% XBB.1.5
3.9% XBB.1.5.15
2.9% XBB.1.9.1
1.8% XBB.1.16
1.5% XBB.1.5.1
1.5% XBB.1.5.17
1.4% XBB.1.5.13
--
0.8% XBB.2.3

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7
Updated: 03/31/23

1/n

Sequence count by US State

#California, #Texas and #NewYork have submitted a big share of sequences with specimen collection dates on or after 03/16/2023

XBB.1.5 is still at the top spot; followed by XBB.1.5.15, XBB.1.9.1 & XBB.1.16

2/n

Granular details -#VariantDashboard #USA #15DayTrends XBB.1.5* (VOI -@WHO) is still ahead of the other lineages!

3/n

.@CDCgov updated variant proportions estimates on 03/31/2023 (updated every Friday)

Expected XBB.1.16 to make an appearance today!

Prudent to start separately tracking XBB.1.5.13 (parent of EK.1* and EK.2*), XBB.1.5.15, XBB.1.16 and XBB.2.3



4/n

XBB.1.16 has the potential to outcompete all other circulating lineages. Everyone is closely watching XBB.1.16 hotspots for clues

Tracker: public.tableau.com/app/profile/ra…

5/n

“Currently, XBB.1.16 is the big dog” ... “It’s picking up mutations that are common in other variants that will increase its advantage further.”

H/T @ErinMPrater @WellatFortune @FortuneMagazine

fortune.com/well/2023/03/3…

6/n

Predicted Immune Escape and ACE2 binding of top lineages in USA (relative to BA.2) Bivalent boosters (OG/Omicron.BA.5) will potentially protect the boosted from getting severe disease/ hospitalizations.

Get updated if you haven't already! public.tableau.com/app/profile/ra……

7/n

USA Airport surveillance update #15DayTrends

106 sequences from 6 US States (#California, #NewYork, #Washington, #NewJersey, #Georgia and #Virginia)

*Includes pooled swabs; Many bad QC seqs

8/n

#Hospital #Capacity - (by State/Division)

All hospitalizations not just COVID-19

public.tableau.com/app/profile/ra……

9/n

#COVID19 #Hospitalizations in the #Unitedstates

>60 yr old & immunocompromised Have a good look at

@CDCgov info on #Boosters!

#Ventilate Indoor spaces Sick? --> Wear a good quality #Mask!

Hospital Tracker (by States, by age group): public.tableau.com/app/profile/ra……

10/n

Circulating recombinant lineages - USA #15DayTrends

XBB.1.5* is still the top recombinant in circulation!

11/n

Status of the latest #COVID19 Wave in #California

Top circulating lineages in CA (#15DayTrends)

XBB.1.5 (68.2%)
XBB.1.5.15 (7.9%)
XBB.1.9.1 (5.6%)
XBB.1.5.13 (1.5%)
BQ.1.1 (1.3%)
XBB.1.16 (1.1%)
XBB.1.9.2 (1.1%)
CH.1.1 (0.9%)

12/n

Status of the latest #COVID19 Wave in #NewYork

Top circulating lineages in NY (#15DayTrends)

XBB.1.5 (71.2%)
XBB.1.9.1 (3.9%)
XBB.1.9.2 (2.2%)
XBB.1.5.17 (2.2%)
XBB.1.5.15 (2.2%)
XBB.1.5.1 (1.7%)
XBB.1.16 (1.3%)
EL.1 (1.3%)

13/n

Status of the latest #COVID19 Wave in #Texas

Top circulating lineages in TX (#15DayTrends)

XBB.1.5 (73.6%)
XBB.1.5.17 (4.4%)
XBB.1.5.15 (4.0%)
XBB.1.16 (2.0%)
XBB.1.5.1 (2.0%)
XBB.1.5.2 (1.2%)
XBB.1.5.21 (1.2%)

14/n