Thread by @RajlabN

#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

52.8% XBB.1.5
9.5% XBB.1.16👀
4.7% XBB.1.9.1
2.6% XBB.1.16.1👀
2.3% XBB.1.9.2
1.3% EG.1
1.2% XBB.2.3
1.2% XBB.1.5.15

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 04/20/23

1/n

Use "Airport Surveillance" (AS) pull-down menu to easily track variant proportions Nationally or by State with or without AS sequences

Top lineages (#15DayTrends w/o AS seqs):

XBB.1.5 (64%),
XBB.1.9.1 (3.8%),
XBB.1.16 (3%),
XBB.1.5.19 (1.6%),
XBB.1.9.2 (1.4%)

2/n

Sequence count by US States

#NewYork & #California have submitted a big share of sequences with specimen collection dates on or after 04/05/2023

XBB.1.5 is still at the top spot; followed by XBB.1.9.1 and XBB.1.16

3/n

Granular details -#VariantDashboard #USA #15DayTrends

XBB.1.5* (VOI -@WHO) is still ahead of the other lineages!

4/n

.@CDCgov updated variant proportions estimates on 04/14/2023 (updated every Friday)

XBB.1.16, XBB.1.9.2 and FD.2 made an entry last week!

Prudent to start tracking XBB.1.5.13 (parent of EK.1* and EK.2*) and XBB.2.3* as well


4/n

XBB.1.16 has the potential to outcompete all other circulating lineages.

Everyone is closely watching XBB.1.16 hotspots for clues

Tracker: public.tableau.com/app/profile/ra…

5/n

XBB.1.16 is one of the fittest variant in circulation right now.. and is picking up additional mutations... "its the one to watch"

H/T @ErinMPrater @WellatFortune
@FortuneMagazine
fortune.com/well/2023/03/3…

6/n

What to know about the XBB.1.16 COVID variant causing concern in India

H/T @ingridhein @medpagetoday
abcnews.go.com/Health/xbb116-…

7/n

Predicted Immune Escape and ACE2 binding of top lineages in USA (relative to BA.2)

Bivalent boosters (OG/Omicron.BA.5) will potentially protect the boosted from getting severe disease/ hospitalizations.

Get updated if you haven't already!

public.tableau.com/app/profile/ra…

8/n

.@CDCgov has authorized a second dose of the bivalent Omicron-BA.5 vaccine for older adults and immunocompromised adults



9/n

#Hospital #Capacity - (by State/Division)

All hospitalizations not just COVID-19

public.tableau.com/app/profile/ra…

10/n

#COVID19 #Hospitalizations in the #UnitedStates

>60 yr old & immunocompromised Have a good look at @CDCgov info on #Boosters!

#Ventilate Indoor spaces

Sick? --> Wear a good quality #Mask!

Hospital Tracker (by States, by age group):public.tableau.com/app/profile/ra…

11/n

Status of the latest #COVID19 Wave in #NewYork #Bellwether #State

Top circulating lineages in NY (#15DayTrends)

XBB.1.5 (49.3%)
XBB.1.16 (16.2%)👀
XBB.1.16.1 (3.7%)👀
XBB.1.9.1 (3.7%)
XBB.1.9.2 (3.7%)
XBB.2.3 (2.2%)
XBB.1.5.37 (2.2%)

12/n

Status of the latest #COVID19 Wave in #California

Top circulating lineages in CA (#15DayTrends)

XBB.1.5 (46%)
XBB.1.16 (17.7%)👀
EG.1 (4.8%)
XBB.1.9.1 (4.8%)
XBB.1.16.1 (3.2%)
XBB.1.5.20 (2.4%)
--
FK.1.1 (1.6%)👀

13/n

Status of the latest #COVID19 Wave in #NewJersey

Top circulating lineages in NJ (#15DayTrends)

XBB.1.5 (34.2%)
XBB.1.16 (29%)👀
XBB.1.16.1 (5.3%)
CH.1.1 (5.3%)
XBB.1.9.1 (5.3%)

[Low sequence count]

14/n

USA Airport surveillance update #15DayTrends

292 sequences from 6 US States (#California, #NewYork, #Washington, #NewJersey, #Georgia and #Virginia) from @CDCgov's Traveler-Based Genomic Surveillance Program.

*Includes pooled swabs & Many bad QC seqs

15/n

As COVID Tracking Wanes, Are We Letting Our Guard Down Too Soon? "Closing up shop too early could mean we are blindsided" “You have to maintain a base level of sequencing for new variants"

H/T @DohenyKathleen @WebMD

webmd.com/covid/news/202…

17/n