,
10 tweets,
4 min read
Read on Twitter
Roger says he might be number one on @ASNCommunities but says a lot of what he writes is wrong #QuantityOverQuality #NKFclinicals
15 years since we learned about the association between gad and NSF. #NKFclinicals
15 cases in Lancet in 2000 by Cowper. ncbi.nlm.nih.gov/pubmed/11041404 #NKFclinicals
Next paper gave it a name Nephrogenic Fibrosing Dermopathy. Histologically similar to wound healing. Cowper started a registry to track cases.
by 2002 49 cases identified. #NKFclinicals
by 2002 49 cases identified. #NKFclinicals
Case reports peak in 2004 and the novelty wears off and case reports in 2005. #NKFclinicals
Has been reported in PD, AKI, and transplant. #NKFclinicals
In 2006 the trigger for NSF, gadolinium, was identified. jasn.asnjournals.org/content/17/9/2…
FDA warning. fda.gov/drugs/drug-saf…
FDA warning. fda.gov/drugs/drug-saf…
No gad no NSF
More Gad more NSF (dose responsive)
Shows up within months to years of exposure
No proven treatment (some data on phototherapy)
#NKFclinicals
More Gad more NSF (dose responsive)
Shows up within months to years of exposure
No proven treatment (some data on phototherapy)
#NKFclinicals
Gd is removed by hemodialysis. Reports of NSF has really gone away. Not sure why. #NKFclinicals
