, 10 tweets, 4 min read Read on Twitter
Gadliunium Fried or Foe by @NephRodby at #NKFclinicals of @Rush_Nephrology
Roger says he might be number one on @ASNCommunities but says a lot of what he writes is wrong #QuantityOverQuality #NKFclinicals
15 years since we learned about the association between gad and NSF. #NKFclinicals
15 cases in Lancet in 2000 by Cowper. ncbi.nlm.nih.gov/pubmed/11041404 #NKFclinicals
Next paper gave it a name Nephrogenic Fibrosing Dermopathy. Histologically similar to wound healing. Cowper started a registry to track cases.
by 2002 49 cases identified. #NKFclinicals
Case reports peak in 2004 and the novelty wears off and case reports in 2005. #NKFclinicals
Has been reported in PD, AKI, and transplant. #NKFclinicals
In 2006 the trigger for NSF, gadolinium, was identified. jasn.asnjournals.org/content/17/9/2…

FDA warning. fda.gov/drugs/drug-saf…
No gad no NSF
More Gad more NSF (dose responsive)
Shows up within months to years of exposure
No proven treatment (some data on phototherapy)

Gd is removed by hemodialysis. Reports of NSF has really gone away. Not sure why. #NKFclinicals
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