Discover and read the best of Twitter Threads about #discovery

Most recents (24)

THREAD Motion to Compel: Per ICR 16 (Idaho Criminal Rule) governing discovery disclosures, sections (a) and (b) the prosecution must provide all exculpatory evidence in its possession and in the possession of its staff and "others" who have participated in the investigation.
This is a broad mandate. The prosecution must also disclose/provide evidence and materials on "written request". #Kohberger has made at least three written discovery requests: a first and two supplementals.
Section (c) governs the defendant's discovery obligations and is limited to evidence the defendant intends to introduce at trial or introduce via testimony at trial. The latter obligation is in response to a written request by prosecution.
Read 14 tweets
پشاور__زیرزمین دو منزلہ گھر کی دریافت
زیرزمین تعمیر (Step Well Art) کابہترین شاہکار
کبھی برصغیرکی دوسری صدی عیسوی کے سب سےبڑےبودھی اسٹوپ (Buddhist Stupas) کے کھنڈرات کوڈھانپے
کبھی گندھارا کی قدیم بدھ سلطنت کادارالحکومت
کبھی گور کھتری مندر ImageImage
مہابت خان مسجد، وکٹوریہ میموریل ہال سمیٹے
کبھی پانچویں صدی کے چینی راہب اورسیاح فاہیان (Chinese Monk and Tourist Faxian) کی تحریروں کاعنوان
کبھی پراساورا اور پورسا پورہ (پورسا کا قصبہ، یا مسکن) کے نام سےپکاراجانے والاموجودہ شہرپشاور (پیش آور، "سرحدی شہر") جسےھندوستان کےمغل بادشاہ Image
جلال الدین اکبر(1556-1605) سے منسوب کیاجاتا رہا، کیا کسی خزانے سے کم ھے؟
حیرتوں کے یہ سلسلے آج بھی جاری ہیں۔
پشاور کے اندرون شہر سرکی گیٹ میں گھر کے ملبے تلے ایک اور دومنزلہ زیر زمین قدیم گھر دریافت ھوا ھے جس پر تحقیق ابھی جاری ھے۔
محکمہ آثار قدیمہ کے مطابق دریافت ھونے ImageImage
Read 4 tweets
As we see videos in social media of the first $PACB PacBio Revio to enter the @broadinstitute , with the promise of the long-read $1000/genome in place, what does it look like today to set up a Next-Generation Sequencing factory/institute?
There have been many of these institutes come and go, and probably the @broadinstitute (Cambridge, US) and the @sangerinstitute (Cambridge, UK) are the two referents in historical terms and in their magnitude of achievements in #genomics. So if we take them as an example, what do
we learn from them?
1) They were successful at being early adopters of large-scale Sanger Sequencing.
2) They were very well funded from the get-go, and contributed in large part to the success of sequencing the reference #human #genome in 2000-2001.
Read 46 tweets
Ready for: "Perspectives on #Metadata Quality and Completeness" with @mragucci Jessica Clark & @AnaHeredia2017 #NisoPlus2023
The Publisher perspective on #MetadataImpact - @mragucci - #Metadata is like #TheForce in #StarWars - it is often invisible but powers so much in research and information exchange #NISOPlus2023 ImageImage
@mragucci Robust standardised #metadata is powerful for all stakeholders in information & knowledge exchange - but practices & standards vary greatly across content types. Ultimately, publishers & content providers have a responsibility to think downstream about the end user #NISOPlus2023 Image
Read 22 tweets
I'm now joining the #NISOPlus23 session: "Making the business case for investing in metadata" with Josh Brown, Heather Kotula, Michelle Urberg, & Julia McDonell
#Metadata #MetadataMatters #NISOPlus
The opportunity costs of poor metadata re-use - Josh Brown from @MoreBrains_Coop
PIDs are keystone metadata! - Powering Reuse, Automation, Aggregation & Analysis
#metadata #NISOPlus23
NOT reusing #metadata has costs in money, time and knock-on effects - rekeying of metadata is essentially unnecessary duplication of effort across sectors, institutions and individuals! #NISOPlus23
Read 19 tweets
A. Wider definition of #pharmacogenomics
B. Pharmacogenomic #variation is common, we are exposed to many #drugs which require pharmacogenomic #guidance
C. There is increasing #evidence of #clinical #utility of #PGx
D. We need more studies on #diversity in #PGx
E. The time is right for #implementation of #PGx #personalised #prescribing…
Read 5 tweets
1/ A THREAD on what $PVCT achieved in 2022. #event #discovery #milestone #milepost. #rosebengal #rosebengalsodium.
2/ $PVCT 2023 Stockholder Letter (released January 9th). . #rosebengal #rosebengalsodium.
3/ $PVCT #clinical and #research collaborators made 6 presentations at 5 medical conferences about PV-10 for different cancers. #ENETS22 #AACR22 #ASCO22 #ISOO2022 #melanomabridge. #presentations. #rosebengal #rosebengalsodium.
Read 50 tweets
1/6 Most of the new #discovery announcements and good first holes ends up as a minor discovery.

How to spot significant discoveries as an investor?
2/6 Three steps to follow🪜:

1) Study significant discoveries
2) Study the failed discoveries
2) Learn the essentials of geology

Let's dig in.
3/6 Do the following:
• Select commodity of interest e.g. #copper #nickel #uranium #gold
• Study top discoveries made in the last years
• Look at announcements (grades, footprint, structures, geophysical anomalies etc.)
• Put it into a system
Read 6 tweets
🧵28 significant #discovery announcements on #ASX this year so far.

Will Santa bring us more discoveries this year?

How many will turn significant over time?
2/5 If you wondering, we had no "significant discovery" announencements since the beginning of October.
3/5 How many of the announced discoveries will turn out to be really significant? We can already see from below graph that market thinks that most of the discovery announcements this year were minor discoveries.
Read 5 tweets
1/ Finally got the full pandemic data file via a FOIA request from #Arlington Public Schools. What follows is a historic account of how the pandemic went in the smallest "self-governing" county in the USA; also one of the wealthiest (7th) and most densely populated (12th).
2/ COVID continues to be a significant, systemic challenge that impacts schools, teachers, kids and their families — as well as education. Data can inform policies to implement for the long run to disrupt COVID & other airborne illnesses.

#CovidIsntOver #COVIDIsAirborne
3/ Data that follows is from APS. Notes: APS stats lack cases from fall 2020, before the Qualtrics system (+100 cases?) Also, APS continuously updates/deletes double records. (Likely +/- 20 records out of more than 9,000 cases in our file.)

APS data:
Read 38 tweets
🧵#Bioinformatics in #drug #discovery and development, a THREAD🧵🧵:
#Bioinformatics is playing an increasingly important role in the discovery and development of new #drugs. In this thread, we'll explore how #bioinformatics is being used to identify new targets for drug intervention and optimize drug design.
One key aspect of #bioinformatics in drug discovery is the identification of potential #drug #targets.
Read 12 tweets
1/x Commonly asked question. What is a significant #mining #discovery? 🧵

In our book it is upper Tier 2, Tier 1 discovery.

Okay, how do these tiers actually work?
Tier 1 deposits have NPV greater than 1 Bln USD. Typical discount rate used is 8% i.e. NPV8

They are rare to find! See the graph below from BHP showing frequency distribution of copper discoveries between 1985-2003.
Tier 2 deposits have NPV of 200-1000 Mln USD.

They are also considered significant by many definitions.
Read 6 tweets
@ABDanielleSmith When is your govt finally going to refer my case file to ASIRT for an independent investigation? Considering that Sean Chu ADMITTED to contravening section 153 and that your Ministers @jasonluan88 & @PonJosephine have publicly supported him AFTER this was public. ImageImageImage
There are endless apparent conflicts of interest, direct connections, public support & donations by many of those in your govt to Sean Chu. Also that very specific details of private conversations re my employment were allegedly leaked to the likes of Craig Chandler & Dan McLean. Image
Allegedly many of my private details & convos w/senior members of your govt have allegedly been shared & leaked by various individuals close to you. I have requested multiple times for this to immediately stop. We know who allegedly threatened to sue me for requesting. #discovery Image
Read 3 tweets
🧬🧵here is a Twitter thread explaining #Bioinformatics in simple terms:🧬🧵
#Bioinformatics is the field that uses computational tools and methods to analyze and interpret #biological #data.
This can include analyzing #DNA and #protein #sequences, predicting the structure and function of #molecules, and modeling biological systems.
Read 7 tweets
Habemus Numbers!!!
During #WBD’s Q3 2022 Earnings Report (JUL-SEP), it’s unveiled 2.8M boost in global DTC subscriptions, citing #HouseOfTheDragon as the main catalyst, but coming below #WallStreet’s 3.3M estimates, reaching 94.9M total #HBOMax+#HBO+#DiscoveryPlus subscribers
1/ Image
According to #WBD, total subscriptions in the US grew 500k, to 53.5M subscribers, and an ARPU of $10.66, a +1.1% increase
Meanwhile overseas markets were the main driver in subscriptions growth, adding 2.3M on Q3 2022, for a 41.4M international total,with an ARPU of just $3.68
Streaming and subscriptions alone were responsible for 2.3B in revenue, -6% compared to Q3 2021.
Ads revenue more than doubled to $106M, as #HBOMax Ad-tier keeps growing in subscribers.
Even so, overall streaming Costs increased +22% to almost 3B, putting DTC -634M in the red.
Read 18 tweets
🚀 We are live! Here is the correct streaming link for all of today's discussions and performances, starting with a panel on complex time with David Krakauer, James Gleick, Ted Chiang, and David Wolpert in a few moments (measured linearly...):

"One of the ideas we had with #InterPlanetary was, 'What would it take to make science hedonistic? And instead of telling people to do it, you'd have to tell people to STOP doing it?"

- SFI President David Krakauer sets the tone for this weekend's celebrations
#IPFest Image
David Krakauer: "Do you have a favorite model or metaphor for #time?"

@JamesGleick: "You've already mentioned a river; that's everybody's favorite. Borges said time is a tiger. People talk about it as a thread. We ONLY talk about time in metaphors." Image
Read 141 tweets
زیر آب مسجد کی دریافت____ریاست بہار (بھارت)
Mosque Re-emerges from Underwater (#Bihar)
تقریباً120 سالہ قدیم
جیسے مصر کی بندرگاہ ہراکلین سے زیر آب شہر اور چین میں زیر آب مجسمہ بدھااور شہر دریافت ھوا ھے بالکل اسی طرح چند دن قبل ریاست بہار
کے ضلع نوادہ کے چرائیلا (Chiraila) گاؤں میں زیر آب مسجد پھولواریہ ڈیم کے جنوبی سرے میں پانی کے خشک ھونےکے بعد ابھری ھے۔
اس زیر آب مسجد کاپس منظریہ ھے کہ یہ 1979 میں پھلواریہ ڈیم کی تعمیرپر کام شروع ھونے سے پہلے موجود تھی جہاں بڑی آبادی تھی جنہیں ڈیم کی تعمیرکیلیے بےدخل کیاگیاتھا۔
پہلے جب پانی کی سطح کم ھوتی تو مسجد کے گنبد کا صرف ایک حصہ نظر آتا تھا جسے لوگ نہیں سمجھ پاتے تھے کہ یہ کیا ھے؟
پرانے زمانے کے لوگ اس مسجد کا نام"نوری مسجد" سے یاد کرتے ہیں جو کہ 1985 میں پھلواریہ ڈیم کی تعمیر کےبعد زیر آب آگئی تھی۔
مسجدکی زمین سے بالائی گنبدتک اونچائی تقریباً 30
Read 5 tweets
Out of 111 significant/major #discovery announcements on #ASX only 12% delivered returns greater than 200% after holding for 12 months.

Key learnings for #portfolio below ⬇️ Image
1. You need a good strategy for separating winners 🏅 from losers 💰.

2. You need to know what winners look like at an early stage. Know what size, grade, geology etc. you are looking for.

If you need help with this I run the course for non geologists.
If you are not good at above 2 points then the size of portfolio actually matters.

Check out analysis by @StrategiesQuant in the thread below ⬇️

Read 4 tweets
Queuing up for tonight's sold out (but streaming) Community Lecture by Fractal Faculty Professor @seanmcarroll!
🧵 Follow this thread as we look into Schröedinger's Box with @seanmcarroll (newly appointed to Chair of #NaturalPhilosphy at @johnshopkins) and learn about the #ManyWorlds hypothesis of #QuantumMechanics:

"Even if we're wrong, it's not magic, it's #physics, it's #science, and it can be understood."

"When we look at the world, we don't see the entirety of reality. What reality is, is the #superposition of the many different ways..."

"#Space is one of the many things in #reality."
Read 24 tweets
Congrats @SamDeBrule @kevinthau @sparkcapital!

A well crafted presentation. Best I've seen recently.

But I think you can push it a little further next round.

I run a pitch design studio, and we audited your deck for fun.

Here are 6 opportunities to make it more compelling. Image
Our story framework informs our recommendations.

We use it to break down content into components.

It's our venture spin on the Story Circle, a timeless structure. Image
Let's start with the great things you're doing.

World-class type and clever branding elements.

Great data. Clear copy. Thorough.

But we think you could dial up the narrative. Image
Read 7 tweets
City for SAFe un jeu largement inspiré de Sim City. Une immersion dans SAFe avec le déroulement accéléré d'un PI Planning, pour construire "Lille Plage" ! Image
Storytelling plutôt bien maîtrisé et clin d'œil appuyé à #RHPS pour cet Agile d'aliénés par @thelor #agilille2022 @NordAgile ImageImageImage
Read 28 tweets
#Arlington #COVID19 #Cases

1/ Unlike Omicron wave, the BA.2 & BA.2.12.1 surge has produced a sustained high level of illness impacting @APSVirginia in May, especially as the system reduced isolation and guaranteed that identified contagious people would return to infect others.
#Arlington #COVID19 #Cases

2/ North Arlington schools saw largest % of their student bodies infected w/COVID. (CDC estimates actual cases 2.3x-9x higher than reported in VA, so these are undercounts.)

Largely unmasked #Discovery, #Taylor, and #Jamestown lead % infected.
#Arlington #COVID19 #Cases

3/ By numbers, #Yorktown High School has many more cases than its peer high schools among students.

High schools also have more staff, and had the most staff cases. Shocking numbers of staff at elementary schools have also gotten sick this year.
Read 9 tweets
#Arlington #COVID19 #Cases

VDH outbreak list now reports 78 linked COVID-19 cases, the result of attending or working at #Taylor elementary school in late April and May. It’s one of the larger documented school outbreaks in Virginia since they began keeping track.
#Arlington #COVID19 #Cases

VDH outbreak list now reports 41 linked COVID-19 cases, the result of attending or working at #ArlingtonTraditional elementary school in May.

The new variants are so contagious spread to family members is extremely common after exposure at school.
#Arlington #COVID19 #Cases

VDH outbreak list now reports 19 linked COVID-19 cases, the result of attending or working at #Discovery elementary school in May.

Why are we tolerating so much COVID in schools and putting infectious kids & teachers back into schools every week?
Read 9 tweets
"I hope to investigate how data cooperatives can rebalance power dynamics in cities, allowing people to learn about themselves and their communities while...using data to advocate for policy and practical solutions in their own best interests." @katyaabaz…
On the Very Serious Podcast: Tyler Cowen on Identifying Talent…
#TalentDevelopment, #TrainingPrograms, #HigherEducation, #ApplePodcast
Read 13 tweets

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