(Note-- this is the sixth time I'm posting this exact same survey, each 5 weeks apart. Links at the end of this thread, but don't compare until you've completed this first, ofc.)
Answer as honestly as possible.
Here we go...
2/ Generally speaking, do you feel *your government* is under-reacting, overreacting, or acting appropriately in response to this pandemic?
3/ Generally speaking, do you feel *the media* is under-reacting, overreacting, or acting appropriately in response to this pandemic?
4/ Generally speaking, do you feel *private citizens* are under-reacting, overreacting, or acting appropriately in response to this pandemic?
5/ What do you predict will be the true fatality rate (percent of those who will die) of this infection once we have stronger testing to find all who are both symptomatic and non-symptomatic?
6/ What number of deaths worldwide do you predict will result from this pandemic?
7/ How soon do you predict we'll have a vaccine for #covid19 approved and widely available to the public?
8/ How many people do you personally know who have been confirmed to have #covid19? (Blood test verified)
9/ Do you consider yourself at high risk if you are infected with #covid19?
10/ [NON-MEDICAL PROFESSIONALS ONLY]
All medical professionals click "(🚫 Doesn't apply to me)"
Are you concerned about your local hospital being able to treat you or your family should they get infected?
11/ [MEDICAL PROFESSIONALS ONLY]
All non-medical professionals click "(🚫 Doesn't apply to me)"
How concerned are you about your hospital or clinic having capacity to meet patient intake for ICU?
12/ How concerned are you for your financial wellbeing in 12 months?
13/ How concerned are you for the financial wellbeing of your country in 12 months?
14/ Thanks for contributing and making it this far!
You can find the original surveys posted exactly 5 weeks apart starting here:
First, let me say that data on this has been a bit limited. But *IF* we do ultimately confirm there are more ApoB-48 (B48) than ApoB-100 (B100) in ASCVD plaque, it would be a very big deal.
Let's unpack...
2/ First, thanks to @TuckerGoodrich for pinging me on these pubs and pressing the discussion.
But also credit to @CaloriesProper on tweeting this a couple years ago (I missed it then)
To understand why this would be so important if true, some review...
3/ B48 and B100s are the major proteins on chylomicrons (CMs) and VLDLs, respectively.
CMs mostly carry lipids from the small intestine to the bloodstream (lipids consumed), VLDL mostly carry lipids from storage; predominantly from adipose stores.
#Me: Why would triglyceride rich LDL particles be more atherogenic than triglyceride poor LDL particles?
#ChatGPT: Triglyceride-rich LDL (low-density lipoprotein) particles are more atherogenic (i.e., more likely to contribute to the… twitter.com/i/web/status/1…
2/
#Me: Couldn’t it also be possible that triglyceride rich LDL are ultimately the result of metabolic dysfunction and that better explains its association with atherosclerosis?
#Me: Is it possible that almost the entire amount of atherogenesis associated with high triglyceride rich LDL is due to dysfunctional lipid metabolism and the diseases that result in these profiles rather than the LDL particles themselves?
1/🧵 I'm definitely a fan of both @DominicDAgosti2 and @DrRagnar (obviously), so I was excited to see them chatting about #lipids, #LMHRs, and Dom's consideration of increasing carbs to lower his #ApoB
3/ When chatting with Dom in SD last year for dinner, he mentioned focusing less on maintaining such a sizable muscle mass as he typically does, and I predicted he'd likely see his LDL/ApoB as considerably higher with this change if still #keto. This podcast appears to confirm...
But I also know many people in my own family who have struggled their whole lives to lose weight and assume if they don't have this near instant drop to their goal weight like <fill in the blank success story> then they are doing it all wrong...
... I can't tell you how many times I point out truly new, record-setting successes with people I know personally -- but it's their own record, their own health journey.
But they often can't see it because they hear they "won't be hungry anymore on <fill in blank diet>"...