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Nov 3, 2020 7 tweets 11 min read Read on X
#Pulmonary Hypertension (pHTN) can really take your breath away!

For today's #MTC, Chief @photon_ick, PGY3 Dr. Armando Martinez, & #CTEPH expert Dr. Demos Papamatheakis reviewed a super cool case of a legit #SPY diagnosed with pHTN & CTEPH, flown to #UCSD for management!
1. pHTN is increased pressure in the #pulmonaryarteries
2. Most common symptoms include: EXERTIONAL #dyspnea, fatigue, pleuritic chest pain, and even #hemoptysis🩸
3. It's typically diagnosed on #ECHO showing dilated arteries, right❤️strain, & elevated RV systolic pressure!
4. There are 5 #WHO Classes of pHTN, distinguished based on physiology and treatment options:
1⃣ Pulmonary Arterial Hypertension
2⃣ pHTN 2/2 LV failure
3⃣ pHTN 2/2 Respiratory/Lung disease
4⃣ CTEPH
5⃣ Other causes Image
5. You can start with an #ECHO, #PFTs, & #VQScan to evaluate for WHO Classes 2-4. If these don't show abnormalities, it might be time for a #RightHeartCath. @ucsdpccm @UCSDCardFellows Image
6. CTEPH is diagnosed by V/Q scan! Or occasionally by CT (or other Angiography). Below you can see normal (top left), and abnormal V/Q scans!!

Proximal & large vessel clots can knock out huge portions of lung perfusion, distal disease takes little pieces, but they can add up!! ImageImageImageImage
7. This disease can be treated #surgically!! Check out how varied these clots can be! They're even graded, with grade 1 being the largest (top left), and grade 4 (bottom right) being those distal little shark teeth. ImageImageImageImage

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More from @ucsdim

Jan 19, 2021
#Infectiousdisease encyclopedia @Darcy_ID_doc carried us through another #HIV-focused #MTC at #Hillcrest this morning!!
Chief @photon_ick & PGY3 Dr. Sheila Bhavsar shared a cool case of #Toxoplasmosis, specifically #Toxo encephalitis!! Check out our 🗝️👇!!
1. Abrupt-onset weakness needs a stroke code evaluation. Our patient presented with #fevers & < 3 hr of L-sided #weakness!! ⏱️=🧠, so this comes first!!

2. Ultimately you'll end up with a #CT scan, where you are really looking for #bleeding or other space-occupying lesions. Image
3. Our patient had contrast-enhancing lesions. #contrastenhancement = edema & mass effect. No enhancement = not space-occupying! This helps narrow our differential! Image
Read 8 tweets
Jan 11, 2021
Hey #MedTwitter!!
This morning at our VA we had Chief @photon_ick give us a case of #ChronicSOB, where it turned out that the patient had #ABPA (#allergic bronchopulmonary #aspergillosis). It's a diagnosis we don't see too often, but one you'll definitely encounter here!! 🗝️👇
This is an #allergic condition, with 2 main predisposing conditions: #asthma & #cysticfibrosis
It can be more rarely seen in other lung disease/immunodeficiencies, but without the right lung environment like this, it is almost NEVER seen!!
There is no universally accepted criteria, but the #ISHAM criteria is often used. Let's check it out!

Traditional obligatory criteria:
- Serum #IgE RAST >0.35 OR Allergic Skin Testing (+) to A. fumigatus
- Total Serum IgE >1000 Image
Read 6 tweets
Jan 5, 2021
Our #residents got to learn about #syncope & #adrenalinsufficiency today from Rising Chief @LizzyHastie, Chief @photon_ick, & Endo-enthusiast @tsantoscavaiola!!

Check out some highlights below we wanted to make sure we shared with our #MedEd peeps on #MedTwitter!! Image
Don’t forget about adrenal insufficiency!! For patients with things like #syncope or #hypotension, it’s easy to forget about cortisol as a cause! While things like dehydration, infection, & other things may be more common overall… AI is #treatable, so make sure you catch it!!
Primary AI = #adrenal glands themselves are the problem. This means #cortisol AND #aldosterone will be low, while #ACTH AND #Renin will be very elevated in attempt to remedy this! Image
Read 5 tweets

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