HRouge Profile picture
26 Jan, 13 tweets, 6 min read
For a long time I thought computational drug modelling really had only one listed company: $SLP

Turns out maybe not: Physiomics #PYC could be a decent candidate for a comp.

Growth is inflecting, it has optionalities and thanks to AIM obscurity it's on a fwd EV/Sales of 6.5x
I first bought $SLP in April 2013. I mention this to make the point that was long before the current bubble in futuristic healthcare stocks, or before SaaS was a thing, this was already a punishingly expensive sector.

Here are the multiples you would've seen back then
Now, $SLP and #PYC are similar but not the same.

SLP was pure software to model drug absorption, sold on licence. It had incredible margins but slow, steady growth. In 2013 it did $10M in revs and in the most recent like-for-like split, FY19, it did $20: ~+10% a year or so
For most of the same period #PYC was flatlining. In 2018 an inflection appears to beging, growth picked up - all organic - and if we call it £1M for FY21 we get the 6.5x multiple from earlier and around a 4x in revenue during which time SLP will more or less have doubled.
#PYC works in modelling tumours and oncological drugs. Description below

Rather than sell software, they use it to consult w/ big pharma and this side of the business is responsible for the numbers above. Loss making, software + consulting project work deserves a lower multiple
Things here are going well: new clients, business development is strong.

6.5x to me at least, already seems an attractive enough multiple for a decent little company on the up, reflecting some mix of software and consulting, the fact they work in oncology and a degree of growth
But the optionalities here may not be priced in at all.

The most exciting is this below: the licencing out of the software they consult with. In short, they'd essentially move more towards a SLP type model and you'd imagine, much higher potential margins than consulting alone.
The second is this: the embedding of their software inside someone else's software.

Post-period - one month ago - this has now happened.
PYC also have been working on a side-gig which hasn't yet been monetised - it's the modelling of personalised medicine dosing for oncology and this has found its way into a trial of $1.3B cap $TRHC Tabula Rasa's own dosing software.
..which in turn has found its way into €18B cap Wolters Kluwer's software.

It's only a tiny cog amongst bigger cogs but a £7M cap has to start somewhere and it looks like they're executing.

As Corero and Trackwise in the UK show, little co's riding on big ones: good thing
What's the Tabula-Wolters thing worth in terms of revenue? I don't know. Initially, not much I suspect.

However, here's an interesting thing: THRC acquired their dosing software side of things for $30M, quickly paid the earn-out and the T9M revs from it? $226K.

Expensive sector
#PYC has £1M in cash, nil debt and recently placed for far more than their annual cash burn. They'll expand operationally and in sales. I'd be pleasantly surprised if they allow themselves to run to breakeven but I doubt they will. I imagine they'll place again in future.
It's by no means anywhere close to the finished article but to me it looks like they're doing everything right. If they keep on executing I wouldn't be surprised if they're a substantially larger and more valuable company in a few years. 6.5x doesn't seem so much to pay for that.

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More from @hareng_rouge

15 Jan
Some notes on TFF Pharmaceuticals $TFFP from the HC Wainwright call

20 mins long, link to call below

sessions.ct.events/tplayer.aspx?s…
This previous thread about TFF was conjecture and I think the Wainwright call gave some grounds to think it may not totally off the mark.

This is again the idea: Pfizer wants to get a powder version of the Covid vaccine in order to avoid the cold-chain issues and expenses associated with the first-gen vaccine Image
Read 8 tweets
13 Jan
Summer 20: investment co with a one holding - a REIT - gets rid of its directors after the REIT collapsed into a zombie.

Sep 20: new management, new investment: a software company with 23% pre-tax margins

Nov 20: 60% growth, big client wins

Implied valuation today <5x sales Image
There are no other numbers, this is everything there is.

The holdco is called Drumz #DRUM a £2.4M cap
The zombie is a listed REIT called KCR
The software company is called Acuity Risk Management

I have it at an implied trailing sales of ~4.9x ex £500K holdco cash and ex zombie Image
Acuity's product is called STREAM, here's how they describe it:

STREAM is a cyber security and risk management software used by organizations globally for ISO 27001, GDPR, NIST and many other standards

In short, its not a nice-to-have for big companies

dataprotectionmagazine.com/?p=136
Read 18 tweets
11 Jan
TLDR: headlines like the below may be masking something interesting at ReNeuron - a medical platform business

As #MXCT and $CLPT show, these sell high

Direct NASDAQ comp valued 5x higher

#RENE platform has an imminent catalyst, which may be derisked.

proactiveinvestors.co.uk/companies/news…
Disclaimers as follows:

- I am far, far out of my lane looking at this
- The comp lives in a bubble market
- This is 100% based on crude pattern recognition
- Market appears to value #RENE for other aspects, so
- This may not work even if the idea proves correct
So, #RENE may have what may be one of the Next Big Things: a platform for the cutting edge of genetic medicine - the comp lives off that alone.

In English, they use "exosomes" to try to get mRNA and CRISPR molecules past the blood-brain barrier into the brain. See below Image
Read 21 tweets
7 Jan
Tiny, UK AIM co in specialty chemicals: specifically "sustainable polymers"

At best this usually means 1 client and a test batch; at worst, magic beans

But Itaconix #ITX is neither and it's rather mispriced: it sells at margins that rival the best in the world - and in size
It may actually be very mispriced; estimates are clearly too low. All in part because it's off the radar.

It's another find by @dopamine_uptake who pointed it out to me after reading on IP Group - some holdings of theirs caught his eye and of them, this one really caught mine.
I'll get straight to it. HY20 end October.

We see revenues up +80% on the previous year's half and they're not far off equaling the whole of 2019's revenues.

Gross margin: 37% - this rings a loud bell

Loss making. Image
Read 26 tweets
5 Jan
Now a £35M cap, a fortnight on

It's one of those small UK if-it-were-listed-in-the-US companies. Bidstack #BIDS and it puts advertising into major online games

It's rocketing - and there are some grounds to think that in quite short order it may be about to turn into a firework
"May" and also:

- history of over promising and disappointing
- very much a AIM small cap
- burns cash
- will place and dilute
- has share price on homepage
- Glassdoor is not great
- emoji issues when discussed
*But* it may now be delivering for real. If so it may also be extremely cheap. How cheap?

20H1 was 2x sequentially and 10x YoY

It may be about to report H1-H2 sequential growth of 5x.

If so, FY20: 10x YoY.

Fwd 21 rev multiple? Perhaps half that number, perhaps even less.
Read 25 tweets
2 Jan
Iceberg might have a point here

$WW is Weight Watchers
Don't worry, not going on a bender with filings

T9M figures last 4 years. Yes it's a bit stagnant in the numbers and costs up / profit down a little etc but the COGs numbers are roughly consistent. You could imagine a jump in revenues flowing through quite well.

2018 was Oprah
Fair to guess lots of New Year gym sign-ups are postponed or never happen and more NY lose weight / get fit resolutions than usual find their way here instead?

Cashflow behaves roughly the same. More SBC, bit more capex.
Read 5 tweets

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