Monday vaccine update:

Back after a short Cornish break, during which the run rate has continued to fall.

189k total doses is down 28%, and 1st doses of 77k are down nearly a half. The 7D total has fallen under 1m, as the number left to do declines, as we'll see next.

1/ Image
18-39 progress:

Over 30 there's little movement now. Under 30, we've probably got around 1.1m still to jab, assuming a final take-up of 72.5%.

Let's look how the numbers have moved over the last week next.

2/ Image
You can see here how little movement there's been in the last week over 30, probably now mainly picking up those making slightly late decisions to get the jab. It's disappointing how poor NI is in comparison to the other countries though.

3/ Image
Under 30, W looks also to be mopping up the last few. E and S are still making reasonable progress, but again NI looks very disappointing, being barely above 50%.

4/ Image
England progress:

We're now 2 weeks from Stage 4 unlocking, so this broadly represents the likely level of protection that will be in place on the 19th.

Given poor (~35%) efficacy after 1 dose, there will still be around 15m adults under 50 without 2 dose protection.

5/ Image
2nd doses of 111k and the 7D total remains at just over 1m a week, consistent with first doses 8 weeks prior. It should drift up to c1.5m a week soon, but no more unless the time period is reduced below 8 weeks.

6/ Image
During the 4 week delay in moving to Stage 4 (allowing for the 2 weeks for protection to kick in), we've jabbed 4.9m with the first dose, and 5.8m with the second dose, rather less than one might have hoped for given the urgency because of Delta's transmission advantage.

7/
It's still not too late to have the jab, and with infections surging again, if anyone is still hesitant but wavering, it's worth remembering that the weakened link between infection and serious illness we can see in the data, is only for those protected by the vaccine.

8/8

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More from @john_actuary

8 Jul
The latest #REACT survey (interim Rd 13) has been published and shows a big jump in infection levels, particularly amongst men.⚽️

Overall levels 🔼from 0.15% to 0.59%, and within Rd 13 doubling time is put at 6 days, (R=1.87).

Rates are 3x higher in the unvaccinated.

1/ Image
Starting with the overall data - this interim report is very up to date, running to the 5th July (Wow! Speedy work @imperialcollege), and you can see the quadrupling of levels since Round 12.

The previous chart shows how they judge that the increase is accelerating.

2/ Image
Between rounds 12 and 13, R is put at 1.32 (doubling time 15 days), but within round 13 it is estimated at 1.87, with a doubling time of just 6 days. These latter estimates do have wider CI's though.

3/ Image
Read 10 tweets
7 Jul
The latest #antibody study from @ONS is out, and shows continued increases in all four countries, with 🏴󠁧󠁢󠁷󠁬󠁳󠁿 now topping 90%. 👏👏

E🔼from 86.6% to 89.8%
W🔼from 88.7% to 91.8%
NI🔼from 85.4% to 87.2%
S🔼from 79.1% to 84.7%

Here's a visual summary of the last three reports.

1/ Image
Note that although the reports are fortnightly, the last one moved the data on three weeks, this one only one week. So that's one reason why the increases are lower. Also, as we get closer to 100%, there will be a natural limit to the increase possible.

2/
You can see that in the youngest age groups, the level of antibodies is around twice the vaccination coverage, with naturally acquired antibodies making up the difference. (ie they have had COVID at some stage.)

3/ Image
Read 7 tweets
6 Jul
The latest @ICNARC report on COVID intensive care activity has been published. It's more comprehensive than ever, so this short thread focuses on recent admission trends. (Outcome data is little changed, being second wave totals.)

Of 536 admiss'ns in June, 43% were in the NW.
1/ Image
536 admissions over a month is still a fraction of the volumes seen at the start of the year, but nevertheless, the recent increase can be seen here. It's a slower rise too, which will be the result of vaccinations (of which more later).

2/ Image
Another reason why the national increase has been slower is it's mainly been concentrated in just one area. You can see here the rise in the NW, compared with figures that, at least so far, barely register in other regions.

3/ Image
Read 14 tweets
26 Jun
Sat vaccine update (excl 🏴󠁧󠁢󠁷󠁬󠁳󠁿)

359k reported today, down 12% on last week, with both 1st and 2nd doses lower.

1st doses of 200k were 8% lower. I estimate there's just over 2m of unsatisfied demand for 1st doses outstanding, so around 11 days worth at the current rate.

1/ Image
Take-up for U40s here. It's a bit strange that NI is so far behind for 30-39, but broadly the same as E and S under 30.

2/ Image
We can see here that the NI figure for 30-39 isn't really moving much, so maybe it will end with a considerably lower take-up?

Under 30, E & S are adding between 1.5% and 2% daily, but again NI is much slower at 0.5%.

3/ ImageImage
Read 4 tweets
25 Jun
Fri vaccine update:

A poor day today, with just under 400k total doses being 15% lower on a week ago.

First doses of 222k were down 9%, which is the real disappointment as we push to complete the younger age groups.

1/ Image
Just a quick summary of the younger ages position today. Under 30, England has now passed 50%. Image
2nd doses of 178k are predictably down 20% on last week, and the 7D total has fallen below 1.2m, consistent with the low run rate of 1st doses 8 weeks ago.

3/ Image
Read 4 tweets
25 Jun
The latest #infection survey from @ONS shows a dramatic increase in S, with increases also in W and E and a small fall in NI.

E 🔼from 0.19% to 0.22% (1 in 440)
W 🔼from 0.07% to 0.12% (1 in 830)
NI 🔽from 0.16% to 0.14% (1 in 720)
S 🔼🔼🔼from 0.17% to 0.46% (1 in 220)

1/ Image
Here's the data, along with the Confidence Intervals.
It's clear that whilst the CI's are much wider for W/S/NI, the S increase is still very significant.

W has bounced around recently but seems to be on an upward trend too, as is E. NI appears more stable.

2/ Image
Regionally, the NW and NE are still on the increase, whereas elsewhere it's a mixed picture. Albeit at lower levels the SW and East are rising too, others appear stable or even possibly falling.

3/ Image
Read 6 tweets

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