Took a Twitter break for several months to help get @NIH #RecoverCOVID up and running to study #LongCovid (AKA #PASC). Thrilled to report @UTHealthSA @UHHospitals have enrolled our first 7 participants! Congrats to them and cast of 1000s working night and day to kick it off. /1
#RecoverCOVID will follow >17K adults, >20K kids across nation + PR for 4 yrs to learn what #LongCovid looks like, how long it lasts, what causes it/increases risk, and, ultimately, what makes it better. Will also include autopsy data and electronic health records of millions. /2
You can find out more about it here recovercovid.org and can sign up to be told more about enrollment opportunities. /3
This is the largest study I have ever seen stood up in such a short time. Credit goes to my co-PIs @nyulangone; Data Core @MassGenBrigham, Biorepository @MayoClinic; hundreds of investigators including @DrDimpyShah, @RachelPatzerPhD, @rhessmd (why are no others on Twitter?) /4
@nih_nhlbi & other @NIH staff, and especially to the patients and advocates who have provided input, materially changing the study, including @DrMarjorieRobe1 @chiluvs1 @ahandvanish @K_Bishof @mhornig & so many more not on Twitter /5
Here are some of the people who need to start using Twitter! Stuart Katz, @abtroxel @nyulangone; Thomas Patterson, Barbara Taylor @UTHealthSA; Grace McComsey, Nora Singer @UHhospitals; Andrea Foulkes, Beth Karlson, Shawn Murphy, Natalie Boutin @MassGenBrigham /6
Mine Cicek, Stephen Thibodeau, Thomas Flotte @MayoClinic

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More from @leorahorwitzmd

10 Jun
Grateful to be part of the team @nyulangone leading the clinical science core for the @NIH long term outcomes of #COVID19 research, to be carried out by dozens of extraordinary investigators around the country. I take this responsibility very seriously. nyulangone.org/news/nyu-lango…
“Post acute sequelae of COVID” (PASC) threatens to have major public health implications for years to come, and patients are suffering now. We must learn more about what causes long term effects, and how they can be treated. For more info, see recovercovid.org.
Need to get my fellow PIs Stuart Katz and Andrea Troxel on Twitter, but meanwhile, thanks and admiration for them too, as well as so many of the faculty and staff @nyulangone who stepped up to kick this work off at light speed.
Read 4 tweets
20 Apr
Excited to judge the finalists for the @SocietyGIM Lipkin Award (best student/resident/fellow abstract) for the third year in a row - tune in live at 12:20p EDT today, tomorrow and Thursday to see recorded presentations and live questions. Our trainees are our future. #SGIM21
Day 1 Image
Day 2 Image
Read 4 tweets
24 Feb
There is no perfect vaccination prioritization strategy, and every choice leaves out people who would really benefit from vaccine. That said, I think @GovNedLamont's new age-based strategy in CT is very sensible if primary goal is to reduce hospitalizations and deaths ASAP. /1
Context: CT has already prioritized those in congregate settings (nursing homes, corrections, group homes, homeless shelters) and those 65+. Now, plan is to go by age in ~3 wk intervals (55-65, 45-54, 35-44, 18-34), last group starts May 3. Teachers now. portal.ct.gov/Coronavirus/CO…
But, don't chronic conditions increase risk from #COVID19? Yes. (In fact, my group was among first to prove it.) So why not prioritize people with them? 1) Because age is an even bigger risk. A young person with comorbidities is still lower risk than an older one without. /3
Read 12 tweets
23 Feb
Today we commemorate half a million US deaths from #COVID19 - a staggering and heartbreaking figure. Millions are mourning. The only positive is that it is increasingly clear that this year will be better. A thread on #COVID19 mortality evidence:
In October we published an analysis showing that death rates among hospitalized #COVID19 patients had dropped precipitously at @nyulangone even after accounting for changes in patient mix. @jhospmedicine journalofhospitalmedicine.com/jhospmed/artic…
Since then, there has been lots of corroborating evidence. This @JAMAInternalMed paper showed that mortality rates at nearly all of 398 US hospitals improved by at least 25% in the first few months of the pandemic (28k hospitalizations) ja.ma/2MdJrTm @rm_werner
Read 8 tweets
17 Feb
So proud of this work led by @vincentjmajor & Erwin Wang w/@NicoleAdlerMD @hauck_kevin @AustrianMd
@yindalon @nyulangone in @nejmcatalyst. This is how to do thoughtful, collaborative integration of #AI into clinical care to create a learning health system catalyst.nejm.org/doi/full/10.10…
At baseline, only 16% of our patients hospitalized within 6 months of death had documentation of advanced care planning. @vincentjmajor & clin colleagues developed 3 predictive models for 2 month mortality, set appropriate threshold (75% PPV), and integrated into the EHR. Image
The alert was shown a max of twice, only to attending physicians. 71% agreed with the alert: 72% of those patients had advanced care planning, vs 34% of those where docs disagreed, so overall 66% of alerted patients had ACP performed. How does that compare to others? Next... Image
Read 6 tweets
6 Dec 20
Our new paper in @JAMANetworkOpen shows no disparity in adjusted outcomes between Black/Hispanic/White #COVID19 patients @nyulangone once hospitalized; if anything, Blacks seem to do a little better. Is this an anomaly? @gbengaogedegbe ja.ma/3n1NKhC /Thread
Actually, several other papers have now found the same. This study of 11,210 hospitalized patients at 92 @ascensionorg hospitals found no sig difference in mortality between Blacks & Whites @BYehia jamanetwork.com/journals/jaman…
This @cdcgov study of 2,491 hospitalized patients at 154 hospitals across the US confirms the findings academic.oup.com/cid/advance-ar…
Read 11 tweets

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