Nov 28 posts will be in the thread below , in this post I am posting the information as we came to know on Nov 26 and 27th and then the thread will continue.
Ctd1) while the UK asks for masking in public transport and shops it leaves schools and also leaves Pubs .Meanwhile Isreal which blocks entry of all foreigners makes an exception
Ctd2) Netherlands finds 13 cases of Omicron variant among passengers from South Africa.It is getting bigger - Israel, Denmark, UK, Australia, Hongkong , the question I am asked is why make these futile efforts- My answer is let's keep trying to stop the deluge ctd)
Ctd3)@USofDisaster asked this very pertinent question about validity of the vast efforts needed to stop entry of a respiratory virus, my take is we need 3 months to prepare
Ctd4) Penny Moore’s team which showed Beta’s ability to dodge immunity “Many mutations we know are problematic, but many more look like they are likely contributing to further evasion, There are even hints 4rm computer modelling that it could dodge immunity conferred by T cells"
Ctd5) The Omicron variant of the coronavirus is probably already circulating in France, its health minister said on Sunday, adding that the government was tightening restrictions to contain its spread.
Ctd6) In flights coming from SA ,of the 600 tested 60 odd were Covid +,further testing showed 13 have # Omicron,just allowing vaccinated without RTPCR to board flights is dangerous.Just consider if there are 13 people in a flight who take off mask to eat at the same time ctd)
Ctd7) There is no way we can prevent an infection to sneak past if we dont have testing 72 hours before, rapid testing before and RTPCR after flights. @michaelmina_lab, @PMOIndia ,@MoHFW_INDIA ,@JM_Scindia, @nvcmenon,@OfficeOf_MM , @PrinSciAdvGoI ,@shekhar_mande ,@BhallaAjay26
Ctd8) There have been questions about the capacity of tests to find the #Omicron, the RTPCR will have equal sensitivity and @michaelmina_lab feels that the Rapid tests will also not lose their effectiveness
@michaelmina_lab Ctd9) Young are coming with Moderate to severe disease, that means they will overwhelm hospitals , REMEMBER that SA just finished a wave of the Delta & then this . Meaning thereby as @fitterhappierAJ and @hjelle_brian said we have bigger problem , I agree.
pbs.org/newshour/healt…
Ctd11) While it serious contention that the #Omicron can evade immunity in more than 90% previously infected causing a huge potential problem in unvaccinated BUT consider Manus where a second wave happened after 75% were infected once , that can recur. 😢
Ctd13) How long do we wait is the next question . Time line to know the answers
Ctd14) Meanwhile UK finds the third one who came to UK, visited Westminister and has now left the country, expectation of 100+ soon. Image
Ctd 15) Twist in the tale , Botswana claims that the new variant came from diplomats of another country. Question is where??africatimes.com/2021/11/28/bot…
Ctd 16) UK in dire straits seemingly by allowing the virus to rip through.

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More from @Rpshahmemorial1

30 Nov
Long thread - The Nov 29th post & the information is all here below in the link posted and after that will be the updates for today ie 30th November@emilygraymd_mph ,@rubyslippahs,@GANyborg ,please add information that may have been missed @itosettiMD_MBA
Ctd1) A summary of what we know new about the current #Omicron, #OmicronVariant is apparently causing more admissions in children?we need to take precautions & vaccinate kids @PMOIndia ,@MoHFW_INDIA , @OfficeOf_MM ,@PrinSciAdvGoI , @shekhar_mande,@NITIAayog,@nvcmenon Image
@PMOIndia @MoHFW_INDIA @OfficeOf_MM @PrinSciAdvGoI @shekhar_mande @NITIAayog @nvcmenon Ctd2) vaccines seem to be working to some degree against the #Omicron in preventing deaths and hospitalizations at least to the information that we know now .#GetVaccinated, #OmicronIsAirborne, #Vaccinessavelives,@rubyslippahs Image
Read 14 tweets
29 Nov
The posts from what we know in the last 3 days across the globe on #Omicron are all at one place here. Feel free to read along . The information from 29th November will follow in the thread below .Currently this is the known Geographic spread #RPSMTrust
Image
Ctd1) So there is a concern that the #Omicron is diversifying pretty fast, that concern in a population where 20% has HIV is a legitimate issue
Ctd2) All Variants of Concern have such clusters of sudden increase of mutations,the issue is they are coming up in an area where only 70% get access to Antiretroviral (HIV Tt) therapy,help needs to go a further step ahead - covid vaccines, antiretrovirals,logistics& Monoclonals
Read 21 tweets
28 Nov
I did a video consult with a family over a child with special needs , we end up discussing the #Omicron and then they say yeah.... we heard it is bad , a few sentences later - " Doctor we haven't been able to go out for our holidays, we are vaxxed can we go to xyz?" Ctd)
Ctd2) I am like " No , the kid is unvaxxed " They - " But we heard on Telly that the kids dont die " . That is how disinformation kills - We know since 1 year that kids with special needs have 6times more incidence of side effects of a Covid infection that a normal kid ctd)
Ctd3) that we need to understand this disinformation system doesnt discuss Long Covid in kids and that is for a purpose, it doesnt suit those running the factories if people dont turn up over fear of infection to their kids , that is why #COVIDisAirborne is not in discussion ctd)
Read 4 tweets
27 Nov
Will try and keep everyone posted on the new developments on Omicron , the last thread became too lengthy in a day .But this is the information we had on 25/ 26 Nov. Ctd
Ctd2) I believe that it has become imperative that we immediately start finding whether the combination of Merck's Molnupiravir &Pfizers Antiviral is effective against Omicron?? we have had reports of Molnupiravir dropping efficacy yesterday in full trial.@hjelle_brian ctd)
@hjelle_brian Ctd3) virologists consider that the virus is " stealing " parts of our RNA as @hjelle_brian, to me it seems that these are efforts of virus to get past Interferons which are our defence mechanism .We know that those with Anti Interferon antibodies have bad course #Omicron ctd)
Read 25 tweets
26 Nov
Long thread 1) There is this fear about the new Botswana/ Nu/ B1.1.159 variant but let's delve into why is this fear?? The 4 cases they found in Botswana were all vaccinated.So what??Breakthrough happens all the time,we underestimate incidence @hjelle_brian ctd)
Ctd2) This variant marked in blue is coming up , so what?? These variants will come and go. Ist it was the Wuhan strain in Grey , then the Beta ( SA strain in Green , then the Delta in Red and now may be the Botswana variant in Blue ( B1.1.529) @MoHFW_INDIA, @mansukhmandviya ctd)
Ctd3) For the virus and also the vaccines ( Pfizer/ Moderna/ AZ) the spike protein is the most important and that is where the maximum risk is . The Delta had 2 changes in spike proteins Receptor Binding Domain, the Beta had 3 while the Nu has 10 , so there is a real risk ctd)
Read 35 tweets
25 Nov
Long Thread - With the new variants one from Botswana and the Second #C13 from South Africa , I am reminded of an old post @hjelle_brian ,@DrEricDing
For a variant to win against the Delta means a new Sumo wrestler is in town and that it has the potential ability to wipe out some of the herd immunity that we have achieved from the Delta .@PrinSciAdvGoI ,@narendramodi,@shekhar_mande ,@OfficeOf_MM

Ctd 3) Also the second variant of interest from Botswana is another one growing ,that means India should immediately stop flights from Africa and also again look at the travel hubs that have flights coming from Africa eg Dubai@HardeepSPuri,@JM_Scindia
Read 4 tweets

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