Mia Malan Profile picture
22 Dec, 11 tweets, 11 min read
[Thread] 1. SA's #Omicron #COVID19 wave seems to have turned (cautiously optimistic view).
@rid1tweets:
1. Much steeper wave than previous waves, but also much shorter
2. Half the nr of days to reach the Omicron peak vs. peaks of other waves

2. The 7 day moving average of new #COVID19 cases for #Omicron (at what seems/could be the peak of the wave) = 23 4237 vs.
- #Delta peak 19,956
- Beta peak 19,042
- D614G peak 12,584

(numbers via @CAPRISAOfficial and @HealthZA)
3. Here are the 7-day moving averages of new #COVID19SA cases, hospitalisations and in-hospital #COVID deaths up until 19 Dec (via @CAPRISAOfficial, @nicd_sa and DATCOV):
- Hospital admissions and deaths, at this stage, still significantly lower than in previous waves.
4. Test positivity rates (% of tests coming out +) until 19 Dec:
1. Mostly 30% +
2. Tu's 7 day-moving average (via @nicd_sa) = 30.1%
5. Provinces: LP, MP, FS, KZN = all show EARLY signs of their #Omicron waves turning.
- Data via @CAPRISAOfficial and @heatlhza)
6. WC, EC = early signs of turning; GP = confirmed to have turned.
@hivepi, @nicd_sa:
- GP cases peaked on 9 Dec @ 97% of #Delta
- GP admissions peaked on 12 Dec @ 46% of Delta
- Deaths peaked @ 8% of Delta (still rising)
bit.ly/3spGthq
7. Northern Cape = no signs of new #COVID19SA cases decreasing by 19 Dec.
8. @Dr_Groome, @nicd_sa:
Diffs between 3rd and 4th wave:
- In 3rd (#Delta) wave provinces started their waves at very different points in time
- In 4th (#Omicron) wave provinces = seeing their increase in cases and start of waves at a much closer point in time
9. Reasons behind fewer hospitalisations/deaths (so less severe disease, at this stage) could be:
1. Up to 70% of population in some provinces = previously infected (natural immunity)
2. Vaccination (44.5% of adults = 1 dose of vaccine)
3. Most hospitalisations = unvaccinated
10. #COVID19 vaccination coverage of adults (18+) in SA up until 19 Dec (via @CAPRISAOfficial and @HealthZA):
- 1 dose: 44%
- fully vaccinated: 39%
11. For the latest data on #Omicron hospitalisations, severity of cases, % of children admitted to hospital in SA, etc, @nicd_sa media briefing at 12 pm today. I'll be live tweeting.

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More from @miamalan

23 Dec
BREAKING [Thread] 1. @SAHPRA1 has approved a 2nd dose of #JnJ and heterologous (mix/match) booster for adults:

1. If u had a JnJ jab, u can get a booster @ least 2 mnths after 1 JnJ shot
2. If u had a #Pfizer jab, u can get a JnJ booster @ least 6 mnths after a 2nd Pfizer jab Image
2. Does @SAHPRA1's approval mean you can have a #Pfizer booster after a #JnJ shot?

NO. It’s only the other way around (a #JnJ booster after a 2nd #Pfizer shot) that has been approved as a “mix and match” booster.
3. Why does @SAHPRA1’s “mix and match” approval not allow for a #Pfizer booster after a #JnJ shot?

Pfizer hasn’t submitted data to Sahpra for approval (#JnJ submitted the data 4 a #JnJ booster after #Pfizer).
Read 18 tweets
22 Dec
[Thread] 1. NEW study on how sick (or not) #Omicron makes people in SA
Full study here: bit.ly/3mo2Y2c (preprint)
2. Cheryl Cohen @nicd_sa:
1. #Omicron emerged in SA when:
- 60-70% of people in SA had been previously infected (so they have natural immunity)
2. Early data suggest less severe disease during the Omicron period
3. #Omicron replaced Delta VERY fast in SA - in Gauteng, where SA's Omicron outbreak started, it replaced Delta within 2 weeks (so it spreads fast).
Read 14 tweets
22 Dec
[Thread] 1. Where does #COVID19 test data in SA come from?
Adrian Puren, @nicd_sa:
1. From people with symptoms who get tested
2. From travelers
3. From both the public and private sector
2. All the #COVID19 testing data is then sent to the NICD and assembled in tables.
3. #COVID19 testing data can be found at these websites:
Read 4 tweets
17 Dec
#JoePhaahla (health min) on #Omicron at Fri's @healthza briefing:

[Thread]

1. Omicron = detected in 76+ countries
2. All SA's 9 provinces = in 4th wave, although NC is still technically entering its 4th wave (but that's according to a calculation formula, not in practice)
2. #JoePhaahla:
1. Although Gauteng = still highest nr of new #COVID19 cases, all 9 provinces in SA have seen a rapid rise in new cases
2. GP (where SA's #Omicron outbreak started): Thu = 27% of new #COVID19 cases vs. 7-10 days ago, GP cases accounted for 70-80% of new cases
3. #JoePhaahla:
The nr of 4th wave #COVID19 cases has exceeded the peaks of waves 1, 2 (Beta), 3 (#Delta)

By how much?
Wave 1: 21 new cases/100,00 people
Wave 2: 32 new cases/100,000 people
Wave 3: 33 new cases/100,000 people
Wave 4 (#Omicron): 37 new cases/100,000 people
Read 11 tweets
17 Dec
What is happening with #COVID19 vaccine boosters + when will SA start?

[Thread]

Nicholas Crisp, @heatlhza:
1. #Pfizer boosters = given 6 mnths after the 2nd dose (that's what Sahpra approved)
2. 1st person = qualify on 28 Dec, @healthza = on that day/shortly thereafter
2. Nicholas Crisp:
1. People who got vaccinated 1st will get boosters 1st because of the 6 month period that need to lapse after the 2nd dose
2. So if you're 50 and went for your Pfizer vaxx before someone who is 60, you will get your booster before the 60 year old person
3. Will SA shorten the 6 month period for a #Pfizer booster after the 2nd dose like some other countries?
1. Sahpra has approved 6 months (not shorter)
2. But Sahpra is looking into data for shorter periods, will announce decision when there's clarity
Read 5 tweets
14 Dec
BREAKING [Thread]: 1. SA’s first real-world data on #Pfizer’s #COVID19 jab’s protection @ #Omicron infection + hospitalisation via @Discovery_SA + @MRCza

Note: This is data from the 1st 3 weeks of the outbreak, so it might change - regard it as preliminary real-world data Image
2. What data are findings based on?
1. @Discovery_SA = SA’s largest health insurer (3.7 mil members)
2. They used 211,000 positive #COVID19 PCR tests of adults (18+)
3. 41% of 211,000 + tests = received 2 doses of #Pfizer ImageImage
3. Here is how #Omicron has progressed in SA:
#Omicron = now 90% of #COVID infections in SA ImageImage
Read 27 tweets

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