Extraordinary immune evasion by #Omicron?
Tested #SARSCoV2 positive today. Despite having three doses of Covid vaccine & past infection in Sep'20! And despite possessing anti-spike Abs higher than post-convalescent titer. So, no respect to hybrid immunity too
Tested #SARSCoV2 positive today. Despite having three doses of Covid vaccine & past infection in Sep'20! And despite possessing anti-spike Abs higher than post-convalescent titer. So, no respect to hybrid immunity too
There are a few takeaways:
1-Prevention of Omicron infection is unattainable with current vaccines.
2-Since majority of infections result in mild illness, our focus shouldn’t be infections & symptomatic disease 1/
1-Prevention of Omicron infection is unattainable with current vaccines.
2-Since majority of infections result in mild illness, our focus shouldn’t be infections & symptomatic disease 1/
3-Furthermore, the amount of NAbs titer needed to neutralise Omicron is several folds (>20-30 folds) higher than previous VOC. This is not attainable with the available vaccines & not even with boosters
4-Antibody titres depend on individual’s genetic makeup and sex 2/
4-Antibody titres depend on individual’s genetic makeup and sex 2/
5-Our focus ought to be the prevention of severe disease and hospitalisation. To achieve that our two doses are probably adequate. 3/
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