1/🧵 You have a COVID ICU patient on benzos who doesn’t respond to needle injection of local anesthetic do to sedatives.
What depth of sedation do you consider this? (it was a CME question just now)
2/ The answer is GENERAL ANESTHESIA, which of course makes sense.
If a person is so deep that he/she doesn’t respond to getting stuck by a needle and the pain of lidocaine injection, that is general!
Why am I writing about this?
3/ Anyone working in the ICU this past few years of #COVID#PANDEMIC is seeing this depth of sedation on a regular basis.
We had almost gotten rid of this by 2019. Then COVID undid progress.
People now think this is normal for some reason.
It is NOT normal.
It is not OK.
4/ In the 1990s, we did this to people all the time and though it was best practice.
For the next 25 years, we all worked globally to prove this depth of sedation (RASS -5, unarousable to painful stimuli) is dangerous.
It accelerates death if used in a prolonged way (days).
5/ This depth of sedation actually brings brain waves in a person’s head to a screeching halt. “BURST SUPPRESSION.”
This is like a flat-line on a heart tracing.
It’s not OK to do this to a person when you don’t need to. All of us are guilty of silencing the brain like this.
6/ We proved that this “putting the person’s brain on the bottom of the ocean floor” depth of sedation is an independent risk factor for increased mortality and for accelerating development of new onset dementia.
7/ COVID patients have enough to deal with in recovery, especially when so many people go on to get #LongCOVID on top of their #PICS.
This is a preventable form of iatrogenic injury to a person.
8/ In addition, this depth of sedation brings on an immense amount of immobilization and subsequent muscle and nerve injury, which makes people unable to walk, do their job, and meet with loved ones.
1/🧵 A personal story of misjudgment as a physician.
Years ago, when I was a young doctor, I had a patient in the ICU on a ventilator who was doing so poorly, day after day, that I was certain he was going to die.
I confidently told the family he was going to die.
2/ The family members all gathered and were extremely distraught. They listened and trusted me.
2/ As part of its efforts, the White House said in a statement that Biden will push to accelerate a $1.5 billion study started last year by the National Institutes of Health to follow 40,000 individuals with and without long Covid to try to better understand the condition.
3/ Biden also proposed spending an additional $25 million on a $50 million study started last year by the Centers for Disease Control and Prevention to understand the risk factors, mechanisms of action and characteristics of long Covid, the White House said.
2/ We all want to relieve the suffering when people are dying of failing kidneys, lungs, hearts.
Transplant can be a great solution.
As a transplant physician myself, I directed lung transplantation at #Vanderbilt.
I worry this new approach is a breech of the dead donor rule.
3/ The “dead donor rule” (DDR) says donors must be determined dead according to established legal/medical criteria PRIOR to procurement of vital organs.
3/ I am drawn in by my patient's weakness, perhaps because I see even greater weakness in myself.
The person in front of me needs the help I can provide by mustering #compassion, the same compassion I seek from others for MY foibles, deficits & inabilities.