Thread by @Primary_Immune

⚠️Potentially dangerous
new 🦠#COVID19 variants🧬
▪️The pandemic won't end until we prevent this phenomenon
❗️Get💉 vaxxed to shield & protect the immunocompromised
ijidonline.com/article/S1201-… #bioinformatics #WomenInSTEM #openscience #snrtg #immunology #genomics #raredisease

. "NOBODY is safe from the virus until
we are ALL safe from the virus"
~Dr. Tedros Ghebreyesus (WHO Director General)

Viruses🦠do strange things when unchallenged for long periods of times in hosts.
Unfortunately mutating🧬is one of those things.

These very prolonged and protracted cases of
persistent SarsCov2 infection🦠*with virus mutations*🧬are completely unique to immunocompromised individuals, with over a dozen documented cases lasting
between 3⃣0⃣0⃣ to 5⃣0⃣0⃣ DAYS.

In comparison: the typical immuno-*competent* individual neutralizes the SarsCov2 🦠virus in 4 to 8 days.

The virus lasted 1⃣0⃣9⃣ days in the patient in the current report - shorter than many of the cases in literature - but adequate time, unfortunately, for the virus 🦠to undergo "evolution" = 🧬mutation.

"An immunosuppressed woman with Hashimoto's thyroiditis harbored a highly unusual SarsCov2 viral genome..."
medrxiv.org/content/10.110… #bioinformatics #openscience #rstats #scicomm #immunology #COVID19

...and another case of persistent, protracted SarsCov2 infection in an immunocompromised patient...
jammi.utpjournals.press/doi/full/10.31… #openscience #scicomm #autoimmune #immunology #raredisease